6714


Homo sapiens (NCBI)

Features
Gene ID: 6714
  
Biological name :
  
Synonyms : ASV|SRC1|THC6|c-SRC|p60-Src / SRC / SRC proto-oncogene, non-receptor tyrosine kinase
  
Possible biological names infered from orthology :
  
Species: Homo sapiens (NCBI)
  
Chr. number:
Strand:
Band:
Gene start:
Gene end:
  
Corresponding Affymetrix probe sets: 1558210_at (Human Genome U133 Plus 2.0 Array)   1558211_s_at (Human Genome U133 Plus 2.0 Array)   1565080_at (Human Genome U133 Plus 2.0 Array)   1565082_x_at (Human Genome U133 Plus 2.0 Array)   213324_at (Human Genome U133 Plus 2.0 Array)   221281_at (Human Genome U133 Plus 2.0 Array)   221284_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: RefSeq - XP_016883516.1
RefSeq - 1034625719
RefSeq - 1034625721
RefSeq - 1034625723
RefSeq - 38202217
RefSeq - 4885609
RefSeq - 768018163
RefSeq - NC_000020.11
RefSeq - NG_023033.1
RefSeq - NP_005408.1
RefSeq - NP_938033.1
RefSeq - XP_011527315.1
RefSeq - XP_016883513.1
RefSeq - XP_016883514.1
RefSeq - XP_016883515.1
RefSeq - 1034625717
RefSeq - NM_005417.4
RefSeq - NM_198291.2
RefSeq - XM_017028026.1
RefSeq - XM_017028027.2
RefSeq - XM_011529013.2
RefSeq - XM_017028024.1
RefSeq - XM_017028025.1
  
See co-cited genes in PubMed
Warning: Please see the Ensembl gene model ENSG00000197122 to get all the annotations available for this gene.


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001545 primary ovarian follicle growth IEA
 biological_processGO:0002223 stimulatory C-type lectin receptor signaling pathway TAS
 biological_processGO:0007049 cell cycle IEA
 biological_processGO:0007165 signal transduction TAS
 biological_processGO:0007169 transmembrane receptor protein tyrosine kinase signaling pathway IBA
 biological_processGO:0007172 signal complex assembly TAS
 biological_processGO:0007173 epidermal growth factor receptor signaling pathway TAS
 biological_processGO:0007179 transforming growth factor beta receptor signaling pathway IMP
 biological_processGO:0007229 integrin-mediated signaling pathway IMP
 biological_processGO:0007411 axon guidance TAS
 biological_processGO:0008283 cell proliferation IEA
 biological_processGO:0009612 response to mechanical stimulus IEA
 biological_processGO:0009615 response to virus IEA
 biological_processGO:0010447 response to acidic pH IEA
 biological_processGO:0010632 regulation of epithelial cell migration IMP
 biological_processGO:0010634 positive regulation of epithelial cell migration IMP
 biological_processGO:0010641 positive regulation of platelet-derived growth factor receptor signaling pathway IEA
 biological_processGO:0010907 positive regulation of glucose metabolic process IEA
 biological_processGO:0010954 positive regulation of protein processing IEA
 biological_processGO:0014911 positive regulation of smooth muscle cell migration IEA
 biological_processGO:0016032 viral process IEA
 biological_processGO:0016236 macroautophagy TAS
 biological_processGO:0018105 peptidyl-serine phosphorylation IEA
 biological_processGO:0018108 peptidyl-tyrosine phosphorylation IMP
 biological_processGO:0022407 regulation of cell-cell adhesion IMP
 biological_processGO:0030154 cell differentiation IBA
 biological_processGO:0030168 platelet activation TAS
 biological_processGO:0030900 forebrain development IEA
 biological_processGO:0031295 T cell costimulation TAS
 biological_processGO:0031648 protein destabilization IEA
 biological_processGO:0031667 response to nutrient levels IEA
 biological_processGO:0031954 positive regulation of protein autophosphorylation IEA
 biological_processGO:0032148 activation of protein kinase B activity IEA
 biological_processGO:0032211 negative regulation of telomere maintenance via telomerase IMP
 biological_processGO:0032463 negative regulation of protein homooligomerization IMP
 biological_processGO:0032869 cellular response to insulin stimulus IEA
 biological_processGO:0033146 regulation of intracellular estrogen receptor signaling pathway IEA
 biological_processGO:0033625 positive regulation of integrin activation TAS
 biological_processGO:0034332 adherens junction organization IEA
 biological_processGO:0034446 substrate adhesion-dependent cell spreading IEA
 biological_processGO:0034614 cellular response to reactive oxygen species IEA
 biological_processGO:0035556 intracellular signal transduction IDA
 biological_processGO:0035635 entry of bacterium into host cell TAS
 biological_processGO:0036035 osteoclast development IBA
 biological_processGO:0036120 cellular response to platelet-derived growth factor stimulus IEA
 biological_processGO:0038083 peptidyl-tyrosine autophosphorylation IBA
 biological_processGO:0038096 Fc-gamma receptor signaling pathway involved in phagocytosis TAS
 biological_processGO:0042127 regulation of cell proliferation IBA
 biological_processGO:0042542 response to hydrogen peroxide IEA
 biological_processGO:0043065 positive regulation of apoptotic process IEA
 biological_processGO:0043066 negative regulation of apoptotic process IMP
 biological_processGO:0043114 regulation of vascular permeability TAS
 biological_processGO:0043149 stress fiber assembly IMP
 biological_processGO:0043154 negative regulation of cysteine-type endopeptidase activity involved in apoptotic process IMP
 biological_processGO:0043393 regulation of protein binding IEA
 biological_processGO:0043406 positive regulation of MAP kinase activity IEA
 biological_processGO:0043552 positive regulation of phosphatidylinositol 3-kinase activity IEA
 biological_processGO:0045056 transcytosis IEA
 biological_processGO:0045087 innate immune response IBA
 biological_processGO:0045124 regulation of bone resorption TAS
 biological_processGO:0045453 bone resorption ISS
 biological_processGO:0045737 positive regulation of cyclin-dependent protein serine/threonine kinase activity IEA
 biological_processGO:0045892 negative regulation of transcription, DNA-templated IEA
 biological_processGO:0045893 positive regulation of transcription, DNA-templated IEA
 biological_processGO:0046628 positive regulation of insulin receptor signaling pathway IEA
 biological_processGO:0046777 protein autophosphorylation IDA
 biological_processGO:0046854 phosphatidylinositol phosphorylation IEA
 biological_processGO:0048010 vascular endothelial growth factor receptor signaling pathway TAS
 biological_processGO:0048011 neurotrophin TRK receptor signaling pathway IEA
 biological_processGO:0048013 ephrin receptor signaling pathway TAS
 biological_processGO:0048477 oogenesis IEA
 biological_processGO:0050715 positive regulation of cytokine secretion IEA
 biological_processGO:0050731 positive regulation of peptidyl-tyrosine phosphorylation IC
 biological_processGO:0050847 progesterone receptor signaling pathway ISS
 biological_processGO:0050900 leukocyte migration TAS
 biological_processGO:0051057 positive regulation of small GTPase mediated signal transduction IMP
 biological_processGO:0051385 response to mineralocorticoid IEA
 biological_processGO:0051602 response to electrical stimulus IEA
 biological_processGO:0051895 negative regulation of focal adhesion assembly ISS
 biological_processGO:0051897 positive regulation of protein kinase B signaling TAS
 biological_processGO:0051902 negative regulation of mitochondrial depolarization IMP
 biological_processGO:0051974 negative regulation of telomerase activity IMP
 biological_processGO:0060065 uterus development IEA
 biological_processGO:0060444 branching involved in mammary gland duct morphogenesis IEA
 biological_processGO:0060491 regulation of cell projection assembly IEA
 biological_processGO:0070374 positive regulation of ERK1 and ERK2 cascade IEA
 biological_processGO:0070555 response to interleukin-1 IMP
 biological_processGO:0071222 cellular response to lipopolysaccharide IEA
 biological_processGO:0071375 cellular response to peptide hormone stimulus ISS
 biological_processGO:0071393 cellular response to progesterone stimulus ISS
 biological_processGO:0071398 cellular response to fatty acid IEA
 biological_processGO:0071456 cellular response to hypoxia IEA
 biological_processGO:0071498 cellular response to fluid shear stress IEA
 biological_processGO:0071803 positive regulation of podosome assembly IEA
 biological_processGO:0071902 positive regulation of protein serine/threonine kinase activity IDA
 biological_processGO:0086098 angiotensin-activated signaling pathway involved in heart process ISS
 biological_processGO:0090263 positive regulation of canonical Wnt signaling pathway IEA
 biological_processGO:0098609 cell-cell adhesion IEA
 biological_processGO:1900182 positive regulation of protein localization to nucleus IEA
 biological_processGO:2000386 positive regulation of ovarian follicle development IEA
 biological_processGO:2000394 positive regulation of lamellipodium morphogenesis IMP
 biological_processGO:2000573 positive regulation of DNA biosynthetic process IEA
 biological_processGO:2000641 regulation of early endosome to late endosome transport IMP
 biological_processGO:2000811 negative regulation of anoikis IMP
 biological_processGO:2001237 negative regulation of extrinsic apoptotic signaling pathway IMP
 biological_processGO:2001243 negative regulation of intrinsic apoptotic signaling pathway IMP
 biological_processGO:2001286 regulation of caveolin-mediated endocytosis IMP
 cellular_componentGO:0002102 podosome IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005737 cytoplasm IDA
 cellular_componentGO:0005739 mitochondrion IDA
 cellular_componentGO:0005743 mitochondrial inner membrane IDA
 cellular_componentGO:0005764 lysosome IDA
 cellular_componentGO:0005770 late endosome IDA
 cellular_componentGO:0005829 cytosol TAS
 cellular_componentGO:0005884 actin filament IEA
 cellular_componentGO:0005886 plasma membrane TAS
 cellular_componentGO:0005901 caveola IDA
 cellular_componentGO:0014069 postsynaptic density IEA
 cellular_componentGO:0031234 extrinsic component of cytoplasmic side of plasma membrane IBA
 cellular_componentGO:0032587 ruffle membrane IEA
 cellular_componentGO:0043005 neuron projection IEA
 cellular_componentGO:0048471 perinuclear region of cytoplasm IEA
 cellular_componentGO:0070062 extracellular exosome HDA
 molecular_functionGO:0004672 protein kinase activity TAS
 molecular_functionGO:0004713 protein tyrosine kinase activity TAS
 molecular_functionGO:0004715 non-membrane spanning protein tyrosine kinase activity TAS
 molecular_functionGO:0005070 SH3/SH2 adaptor activity TAS
 molecular_functionGO:0005080 protein kinase C binding IEA
 molecular_functionGO:0005102 signaling receptor binding IPI
 molecular_functionGO:0005158 insulin receptor binding IEA
 molecular_functionGO:0005178 integrin binding TAS
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0008022 protein C-terminus binding IPI
 molecular_functionGO:0016301 kinase activity TAS
 molecular_functionGO:0019899 enzyme binding IPI
 molecular_functionGO:0019900 kinase binding IPI
 molecular_functionGO:0020037 heme binding IDA
 molecular_functionGO:0030331 estrogen receptor binding IEA
 molecular_functionGO:0031625 ubiquitin protein ligase binding IEA
 molecular_functionGO:0042169 SH2 domain binding IPI
 molecular_functionGO:0044325 ion channel binding IPI
 molecular_functionGO:0045296 cadherin binding HDA
 molecular_functionGO:0046875 ephrin receptor binding IPI
 molecular_functionGO:0046934 phosphatidylinositol-4,5-bisphosphate 3-kinase activity TAS
 molecular_functionGO:0051219 phosphoprotein binding IPI
 molecular_functionGO:0051427 hormone receptor binding IBA
 molecular_functionGO:0070851 growth factor receptor binding IPI
 molecular_functionGO:0071253 connexin binding IEA
 molecular_functionGO:0097110 scaffold protein binding IPI


Pathways (from Reactome)
Pathway description
No match


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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