6721


Homo sapiens (NCBI)

Features
Gene ID: 6721
  
Biological name :
  
Synonyms : SREBF2 / SREBP-2|SREBP2|bHLHd2 / sterol regulatory element binding transcription factor 2
  
Possible biological names infered from orthology :
  
Species: Homo sapiens (NCBI)
  
Chr. number:
Strand:
Band:
Gene start:
Gene end:
  
Corresponding Affymetrix probe sets: 201247_at (Human Genome U133 Plus 2.0 Array)   201248_s_at (Human Genome U133 Plus 2.0 Array)   242748_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: RefSeq - NC_000022.11
RefSeq - 1034629376
RefSeq - XP_006724373.1
RefSeq - XP_011528649.1
RefSeq - XP_016884410.1
RefSeq - XP_016884411.1
RefSeq - NP_004590.2
RefSeq - 27477113
RefSeq - 1034629373
RefSeq - 578837368
RefSeq - 768025636
RefSeq - XR_001755278.2
RefSeq - NM_004599.3
RefSeq - NR_103834.1
RefSeq - XM_006724310.3
RefSeq - XM_011530347.2
RefSeq - XM_017028921.2
RefSeq - XM_017028922.2
RefSeq - XR_001755276.2
RefSeq - XR_001755277.2
  
See co-cited genes in PubMed
Warning: Please see the Ensembl gene model ENSG00000198911 to get all the annotations available for this gene.


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000122 negative regulation of transcription by RNA polymerase II IDA
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006629 lipid metabolic process TAS
 biological_processGO:0008203 cholesterol metabolic process IEA
 biological_processGO:0009267 cellular response to starvation IMP
 biological_processGO:0010886 positive regulation of cholesterol storage IDA
 biological_processGO:0042632 cholesterol homeostasis IEA
 biological_processGO:0045540 regulation of cholesterol biosynthetic process TAS
 biological_processGO:0045944 positive regulation of transcription by RNA polymerase II IDA
 biological_processGO:0071404 cellular response to low-density lipoprotein particle stimulus IEP
 biological_processGO:0071499 cellular response to laminar fluid shear stress NAS
 biological_processGO:0072368 regulation of lipid transport by negative regulation of transcription from RNA polymerase II promoter IDA
 biological_processGO:0090370 negative regulation of cholesterol efflux IDA
 biological_processGO:1903146 regulation of autophagy of mitochondrion HMP
 biological_processGO:1903955 positive regulation of protein targeting to mitochondrion HMP
 cellular_componentGO:0000139 Golgi membrane TAS
 cellular_componentGO:0005634 nucleus IDA
 cellular_componentGO:0005654 nucleoplasm TAS
 cellular_componentGO:0005737 cytoplasm IDA
 cellular_componentGO:0005739 mitochondrion IDA
 cellular_componentGO:0005783 endoplasmic reticulum IDA
 cellular_componentGO:0005789 endoplasmic reticulum membrane TAS
 cellular_componentGO:0005829 cytosol TAS
 cellular_componentGO:0012507 ER to Golgi transport vesicle membrane IEA
 cellular_componentGO:0032937 SREBP-SCAP-Insig complex IDA
 cellular_componentGO:0043231 intracellular membrane-bounded organelle IDA
 molecular_functionGO:0000247 C-8 sterol isomerase activity IDA
 molecular_functionGO:0000978 RNA polymerase II proximal promoter sequence-specific DNA binding IDA
 molecular_functionGO:0000981 RNA polymerase II transcription factor activity, sequence-specific DNA binding NAS
 molecular_functionGO:0001078 transcriptional repressor activity, RNA polymerase II proximal promoter sequence-specific DNA binding IDA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0008022 protein C-terminus binding IPI
 molecular_functionGO:0046983 protein dimerization activity IEA
 molecular_functionGO:0070888 E-box binding IDA


Pathways (from Reactome)
Pathway description
No match


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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