6857


Homo sapiens (NCBI)
bindingvesiclemembraneregulationsynapticcalciumproteinexocytosisclathrin-sculptedtransportiontransmissionneurotransmittersecretionion-dependentfusionglutamategranulesnareneuronprojectioncalcium-dependentsyntaxin-detectionchemicalbraindevelopmentdopaminedockingendocytosis

Features
Gene ID: 6857
  
Biological name :
  
Synonyms : P65|SVP65|SYT / synaptotagmin 1 / SYT1
  
Possible biological names infered from orthology :
  
Species: Homo sapiens (NCBI)
  
Chr. number:
Strand:
Band:
Gene start:
Gene end:
  
Corresponding Affymetrix probe sets: 203998_s_at (Human Genome U133 Plus 2.0 Array)   203999_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: RefSeq - 209447070
RefSeq - 209447073
RefSeq - 5032139
RefSeq - 530400757
RefSeq - 578824170
RefSeq - 631790805
RefSeq - 767975224
RefSeq - NC_000012.12
RefSeq - NP_001129277.1
RefSeq - NP_001129278.1
RefSeq - NP_001278830.1
RefSeq - NP_005630.1
RefSeq - XP_005269170.1
RefSeq - XP_006719639.1
RefSeq - XP_011537012.1
RefSeq - NM_001135805.1
RefSeq - NM_001135806.1
RefSeq - NM_001291901.1
RefSeq - NM_005639.2
RefSeq - XM_011538710.2
RefSeq - XM_005269113.3
RefSeq - XM_006719576.1
  
See co-cited genes in PubMed
Warning: Please see the Ensembl gene model ENSG00000067715 to get all the annotations available for this gene.


Gene Ontology (GO)
response to chemicaldetection of stimuluscellular component organizationestablishment of localizationcell communicationregulation of biological qualitycellular localizationanatomical structure developmentmembrane dockingcellular component biogenesiscellular response to stimuluscellular developmental processcell growthdevelopmental growthresponse to chemicaldetection of stimuluscellular component organizationestablishment of localizationcell communicationregulation of biological qualitycellular localizationanatomical structure developmentmembrane dockingcellular component biogenesiscellular response to stimuluscellular developmental processcell growthdevelopmental growthresponse to chemicaldetection of stimuluscellular component organizationestablishment of localizationcell communicationregulation of biological qualitycellular localizationanatomical structure developmentmembrane dockingcellular component biogenesiscellular response to stimuluscellular developmental processcell growthdevelopmental growthresponse to chemicaldetection of stimuluscellular component organizationestablishment of localizationcell communicationregulation of biological qualitycellular localizationanatomical structure developmentmembrane dockingcellular component biogenesiscellular response to stimuluscellular developmental processcell growthdevelopmental growthresponse to chemicaldetection of stimuluscellular component organizationestablishment of localizationcell communicationregulation of biological qualitycellular localizationanatomical structure developmentmembrane dockingcellular component biogenesiscellular response to stimuluscellular developmental processcell growthdevelopmental growthresponse to chemicaldetection of stimuluscellular component organizationestablishment of localizationcell communicationregulation of biological qualitycellular localizationanatomical structure developmentmembrane dockingcellular component biogenesiscellular response to stimuluscellular developmental processcell growthdevelopmental growthresponse to chemicaldetection of stimuluscellular component organizationestablishment of localizationcell communicationregulation of biological qualitycellular localizationanatomical structure developmentmembrane dockingcellular component biogenesiscellular response to stimuluscellular developmental processcell growthdevelopmental growthresponse to chemicaldetection of stimuluscellular component organizationestablishment of localizationcell communicationregulation of biological qualitycellular localizationanatomical structure developmentmembrane dockingcellular component biogenesiscellular response to stimuluscellular developmental processcell growthdevelopmental growthresponse to chemicaldetection of stimuluscellular component organizationestablishment of localizationcell communicationregulation of biological qualitycellular localizationanatomical structure developmentmembrane dockingcellular component biogenesiscellular response to stimuluscellular developmental processcell growthdevelopmental growthresponse to chemicaldetection of stimuluscellular component organizationestablishment of localizationcell communicationregulation of biological qualitycellular localizationanatomical structure developmentmembrane dockingcellular component biogenesiscellular response to stimuluscellular developmental processcell growthdevelopmental growthresponse tresponse to chemicaldetection detection of stimuluscellular ccellular component organizationestablishmestablishment of localizationcell commucell communicationregulationregulation of biological qualitycellular lcellular localizationanatomicalanatomical structure developmentmembrane dmembrane dockingcellular ccellular component biogenesiscellular rcellular response to stimuluscellular dcellular developmental processcell growtcell growthdevelopmendevelopmental growth
protein bindinglipid bindingion bindingmodified amino acid bindingprotein bindinglipid bindingion bindingmodified amino acid bindingprotein bindinglipid bindingion bindingmodified amino acid bindingprotein bindinglipid bindingion bindingmodified amino acid bindingprotein bindinglipid bindingion bindingmodified amino acid bindingprotein bindinglipid bindingion bindingmodified amino acid bindingprotein bindinglipid bindingion bindingmodified amino acid bindingprotein bindinglipid bindingion bindingmodified amino acid bindingprotein bindinglipid bindingion bindingmodified amino acid bindingprotein bindinglipid bindingion bindingmodified amino acid bindingprotein bindingprotein bindinglipid bindinglipid bindingion bindingion bindingmodified amino acid bindingmodified amino acid binding
cellorganellemembranesynapsecell junctionprotein-containing complexcellorganellemembranesynapsecell junctionprotein-containing complexcellorganellemembranesynapsecell junctionprotein-containing complexcellorganellemembranesynapsecell junctionprotein-containing complexcellorganellemembranesynapsecell junctionprotein-containing complexcellorganellemembranesynapsecell junctionprotein-containing complexcellorganellemembranesynapsecell junctionprotein-containing complexcellorganellemembranesynapsecell junctionprotein-containing complexcellorganellemembranesynapsecell junctionprotein-containing complexcellorganellemembranesynapsecell junctionprotein-containing complexcellcellorganelleorganellemembranemembranesynapsesynapsecell junctioncell junctionprotein-containing compprotein-containing complex
TypeGO IDTermEv.Code
 biological_processGO:0005513 detection of calcium ion TAS
 biological_processGO:0006906 vesicle fusion IBA
 biological_processGO:0007268 chemical synaptic transmission TAS
 biological_processGO:0007269 neurotransmitter secretion TAS
 biological_processGO:0007420 brain development IEA
 biological_processGO:0014047 glutamate secretion TAS
 biological_processGO:0014059 regulation of dopamine secretion IEA
 biological_processGO:0016079 synaptic vesicle exocytosis IBA
 biological_processGO:0017157 regulation of exocytosis TAS
 biological_processGO:0017158 regulation of calcium ion-dependent exocytosis IBA
 biological_processGO:0031340 positive regulation of vesicle fusion IEA
 biological_processGO:0045956 positive regulation of calcium ion-dependent exocytosis IEA
 biological_processGO:0048278 vesicle docking IEA
 biological_processGO:0048488 synaptic vesicle endocytosis IBA
 biological_processGO:0048791 calcium ion-regulated exocytosis of neurotransmitter IBA
 biological_processGO:0050806 positive regulation of synaptic transmission ISS
 biological_processGO:0051260 protein homooligomerization TAS
 biological_processGO:0051291 protein heterooligomerization IEA
 biological_processGO:0051966 regulation of synaptic transmission, glutamatergic ISS
 biological_processGO:0061024 membrane organization TAS
 biological_processGO:0071277 cellular response to calcium ion ISS
 biological_processGO:0098746 fast, calcium ion-dependent exocytosis of neurotransmitter ISS
 biological_processGO:1903305 regulation of regulated secretory pathway ISS
 biological_processGO:1903861 positive regulation of dendrite extension IDA
 cellular_componentGO:0005737 cytoplasm IDA
 cellular_componentGO:0005794 Golgi apparatus IEA
 cellular_componentGO:0005886 plasma membrane TAS
 cellular_componentGO:0008021 synaptic vesicle TAS
 cellular_componentGO:0030054 cell junction IEA
 cellular_componentGO:0030285 integral component of synaptic vesicle membrane IEA
 cellular_componentGO:0030424 axon IEA
 cellular_componentGO:0030665 clathrin-coated vesicle membrane TAS
 cellular_componentGO:0030672 synaptic vesicle membrane TAS
 cellular_componentGO:0031045 dense core granule IEA
 cellular_componentGO:0031201 SNARE complex IEA
 cellular_componentGO:0042584 chromaffin granule membrane IEA
 cellular_componentGO:0042734 presynaptic membrane IEA
 cellular_componentGO:0043005 neuron projection ISS
 cellular_componentGO:0044306 neuron projection terminus IEA
 cellular_componentGO:0060076 excitatory synapse IEA
 cellular_componentGO:0060201 clathrin-sculpted acetylcholine transport vesicle membrane TAS
 cellular_componentGO:0060203 clathrin-sculpted glutamate transport vesicle membrane TAS
 cellular_componentGO:0061202 clathrin-sculpted gamma-aminobutyric acid transport vesicle membrane TAS
 cellular_componentGO:0070083 clathrin-sculpted monoamine transport vesicle membrane TAS
 molecular_functionGO:0000149 SNARE binding ISS
 molecular_functionGO:0001786 phosphatidylserine binding IEA
 molecular_functionGO:0005509 calcium ion binding IBA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0005516 calmodulin binding IEA
 molecular_functionGO:0005544 calcium-dependent phospholipid binding TAS
 molecular_functionGO:0005545 1-phosphatidylinositol binding TAS
 molecular_functionGO:0005546 phosphatidylinositol-4,5-bisphosphate binding IBA
 molecular_functionGO:0008022 protein C-terminus binding IEA
 molecular_functionGO:0017075 syntaxin-1 binding TAS
 molecular_functionGO:0019905 syntaxin binding IBA
 molecular_functionGO:0030276 clathrin binding IBA
 molecular_functionGO:0030348 syntaxin-3 binding IEA
 molecular_functionGO:0042802 identical protein binding IEA
 molecular_functionGO:0046982 protein heterodimerization activity IEA
 molecular_functionGO:0048306 calcium-dependent protein binding IEA
 molecular_functionGO:0050750 low-density lipoprotein particle receptor binding IDA


Pathways (from Reactome)
Pathway description
No match


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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