6928


Homo sapiens (NCBI)
regulationtranscriptioncellrnapolymeraseiibindingdevelopmentactivityfactorsequence-specificspecificationdifferentiationresponsemorphogenesisinvolvedcomplexdnaproteinendodermalfatedna-templatedsignalingpathwaypronephrosnephronbranchingepithelialpromoterureteric

Features
Gene ID: 6928
  
Biological name :
  
Synonyms : FJHN|HNF-1-beta|HNF-1B|HNF1beta|HNF2|HPC11|LF-B3|LFB3|MODY5|TCF-2|TCF2|VHNF1 / HNF1B / HNF1 homeobox B
  
Possible biological names infered from orthology :
  
Species: Homo sapiens (NCBI)
  
Chr. number:
Strand:
Band:
Gene start:
Gene end:
  
Corresponding Affymetrix probe sets: 205313_at (Human Genome U133 Plus 2.0 Array)   208135_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: RefSeq - XP_011523466.1
RefSeq - 4507397
RefSeq - 747165384
RefSeq - 767995700
RefSeq - 767995702
RefSeq - 767995704
RefSeq - 767995706
RefSeq - 767995708
RefSeq - NC_000017.11
RefSeq - NG_013019.2
RefSeq - NP_000449.1
RefSeq - NP_001159395.1
RefSeq - NP_001291215.1
RefSeq - NT_187614.1
RefSeq - XP_011523462.1
RefSeq - XP_011523463.1
RefSeq - XP_011523464.1
RefSeq - XP_011523465.1
RefSeq - 260064065
RefSeq - NM_000458.3
RefSeq - NM_001165923.3
RefSeq - NM_001304286.1
RefSeq - NM_006481.1
RefSeq - XM_011525161.1
RefSeq - XM_011525162.2
RefSeq - XM_011525163.2
RefSeq - XM_011525164.1
RefSeq - XM_011525160.1
  
See co-cited genes in PubMed
Warning: Please see the Ensembl gene model ENSG00000275410 to get all the annotations available for this gene.


Gene Ontology (GO)
nitrogen compound metabolic processbiosynthetic processcellular metabolic processprimary metabolic processorganic substance metabolic processanatomical structure developmentcellular developmental processcell communicationcellular response to stimulusresponse to chemicalmacromolecule localizationestablishment of localizationregulation of biological qualitycircadian rhythmepithelial cell proliferationcellular component organizationcellular component biogenesisdevelopmental growthmaintenance of cell numbercell deathnitrogen compound metabolic processbiosynthetic processcellular metabolic processprimary metabolic processorganic substance metabolic processanatomical structure developmentcellular developmental processcell communicationcellular response to stimulusresponse to chemicalmacromolecule localizationestablishment of localizationregulation of biological qualitycircadian rhythmepithelial cell proliferationcellular component organizationcellular component biogenesisdevelopmental growthmaintenance of cell numbercell deathnitrogen compound metabolic processbiosynthetic processcellular metabolic processprimary metabolic processorganic substance metabolic processanatomical structure developmentcellular developmental processcell communicationcellular response to stimulusresponse to chemicalmacromolecule localizationestablishment of localizationregulation of biological qualitycircadian rhythmepithelial cell proliferationcellular component organizationcellular component biogenesisdevelopmental growthmaintenance of cell numbercell deathnitrogen compound metabolic processbiosynthetic processcellular metabolic processprimary metabolic processorganic substance metabolic processanatomical structure developmentcellular developmental processcell communicationcellular response to stimulusresponse to chemicalmacromolecule localizationestablishment of localizationregulation of biological qualitycircadian rhythmepithelial cell proliferationcellular component organizationcellular component biogenesisdevelopmental growthmaintenance of cell numbercell deathnitrogen compound metabolic processbiosynthetic processcellular metabolic processprimary metabolic processorganic substance metabolic processanatomical structure developmentcellular developmental processcell communicationcellular response to stimulusresponse to chemicalmacromolecule localizationestablishment of localizationregulation of biological qualitycircadian rhythmepithelial cell proliferationcellular component organizationcellular component biogenesisdevelopmental growthmaintenance of cell numbercell deathnitrogen compound metabolic processbiosynthetic processcellular metabolic processprimary metabolic processorganic substance metabolic processanatomical structure developmentcellular developmental processcell communicationcellular response to stimulusresponse to chemicalmacromolecule localizationestablishment of localizationregulation of biological qualitycircadian rhythmepithelial cell proliferationcellular component organizationcellular component biogenesisdevelopmental growthmaintenance of cell numbercell deathnitrogen compound metabolic processbiosynthetic processcellular metabolic processprimary metabolic processorganic substance metabolic processanatomical structure developmentcellular developmental processcell communicationcellular response to stimulusresponse to chemicalmacromolecule localizationestablishment of localizationregulation of biological qualitycircadian rhythmepithelial cell proliferationcellular component organizationcellular component biogenesisdevelopmental growthmaintenance of cell numbercell deathnitrogen compound metabolic processbiosynthetic processcellular metabolic processprimary metabolic processorganic substance metabolic processanatomical structure developmentcellular developmental processcell communicationcellular response to stimulusresponse to chemicalmacromolecule localizationestablishment of localizationregulation of biological qualitycircadian rhythmepithelial cell proliferationcellular component organizationcellular component biogenesisdevelopmental growthmaintenance of cell numbercell deathnitrogen compound metabolic processbiosynthetic processcellular metabolic processprimary metabolic processorganic substance metabolic processanatomical structure developmentcellular developmental processcell communicationcellular response to stimulusresponse to chemicalmacromolecule localizationestablishment of localizationregulation of biological qualitycircadian rhythmepithelial cell proliferationcellular component organizationcellular component biogenesisdevelopmental growthmaintenance of cell numbercell deathnitrogen compound metabolic processbiosynthetic processcellular metabolic processprimary metabolic processorganic substance metabolic processanatomical structure developmentcellular developmental processcell communicationcellular response to stimulusresponse to chemicalmacromolecule localizationestablishment of localizationregulation of biological qualitycircadian rhythmepithelial cell proliferationcellular component organizationcellular component biogenesisdevelopmental growthmaintenance of cell numbercell deathnitrogenitrogen compound metabolic processbiosyntbiosynthetic processcellulacellular metabolic processprimaryprimary metabolic processorganicorganic substance metabolic processanatomianatomical structure developmentcellulacellular developmental processcell cocell communicationcellulacellular response to stimulusresponsresponse to chemicalmacromomacromolecule localizationestabliestablishment of localizationregulatregulation of biological qualitycircadicircadian rhythmepithelepithelial cell proliferationcellulacellular component organizationcellulacellular component biogenesisdevelopdevelopmental growthmaintenmaintenance of cell numbercell decell death
organic cyclic compound bindingheterocyclic compound bindingDNA-binding transcription factor activityprotein bindingprotein-containing complex bindingorganic cyclic compound bindingheterocyclic compound bindingDNA-binding transcription factor activityprotein bindingprotein-containing complex bindingorganic cyclic compound bindingheterocyclic compound bindingDNA-binding transcription factor activityprotein bindingprotein-containing complex bindingorganic cyclic compound bindingheterocyclic compound bindingDNA-binding transcription factor activityprotein bindingprotein-containing complex bindingorganic cyclic compound bindingheterocyclic compound bindingDNA-binding transcription factor activityprotein bindingprotein-containing complex bindingorganic cyclic compound bindingheterocyclic compound bindingDNA-binding transcription factor activityprotein bindingprotein-containing complex bindingorganic cyclic compound bindingheterocyclic compound bindingDNA-binding transcription factor activityprotein bindingprotein-containing complex bindingorganic cyclic compound bindingheterocyclic compound bindingDNA-binding transcription factor activityprotein bindingprotein-containing complex bindingorganic cyclic compound bindingheterocyclic compound bindingDNA-binding transcription factor activityprotein bindingprotein-containing complex bindingorganic cyclic compound bindingheterocyclic compound bindingDNA-binding transcription factor activityprotein bindingprotein-containing complex bindingorganic cyclic compound bindorganic cyclic compound bindingheterocyclic compound bindinheterocyclic compound bindingDNA-binding transcription faDNA-binding transcription factor activityprotein bindingprotein bindingprotein-containing complex bprotein-containing complex binding
cellorganellemembrane-enclosed lumenprotein-containing complexcellorganellemembrane-enclosed lumenprotein-containing complexcellorganellemembrane-enclosed lumenprotein-containing complexcellorganellemembrane-enclosed lumenprotein-containing complexcellorganellemembrane-enclosed lumenprotein-containing complexcellorganellemembrane-enclosed lumenprotein-containing complexcellorganellemembrane-enclosed lumenprotein-containing complexcellorganellemembrane-enclosed lumenprotein-containing complexcellorganellemembrane-enclosed lumenprotein-containing complexcellorganellemembrane-enclosed lumenprotein-containing complexcellcellorganelleorganellemembrane-enclosed lumenmembrane-enclosed lumenprotein-containing complexprotein-containing complex
TypeGO IDTermEv.Code
 biological_processGO:0000122 negative regulation of transcription by RNA polymerase II IEA
 biological_processGO:0001714 endodermal cell fate specification IEA
 biological_processGO:0001822 kidney development IMP
 biological_processGO:0001826 inner cell mass cell differentiation IEA
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006357 regulation of transcription by RNA polymerase II IBA
 biological_processGO:0007219 Notch signaling pathway IEA
 biological_processGO:0009749 response to glucose IEA
 biological_processGO:0009952 anterior/posterior pattern specification IEA
 biological_processGO:0014070 response to organic cyclic compound IEA
 biological_processGO:0030073 insulin secretion IEA
 biological_processGO:0030111 regulation of Wnt signaling pathway IEA
 biological_processGO:0030902 hindbrain development IEA
 biological_processGO:0032922 circadian regulation of gene expression IEA
 biological_processGO:0035565 regulation of pronephros size IMP
 biological_processGO:0039020 pronephric nephron tubule development IGI
 biological_processGO:0042493 response to drug IEA
 biological_processGO:0042663 regulation of endodermal cell fate specification IEA
 biological_processGO:0045893 positive regulation of transcription, DNA-templated IDA
 biological_processGO:0048557 embryonic digestive tract morphogenesis IEA
 biological_processGO:0048754 branching morphogenesis of an epithelial tube IEA
 biological_processGO:0048793 pronephros development IMP
 biological_processGO:0050673 epithelial cell proliferation IEA
 biological_processGO:0060261 positive regulation of transcription initiation from RNA polymerase II promoter IDA
 biological_processGO:0060677 ureteric bud elongation IEA
 biological_processGO:0061017 hepatoblast differentiation IEA
 biological_processGO:0061296 negative regulation of mesenchymal cell apoptotic process involved in mesonephric nephron morphogenesis IEA
 biological_processGO:0065004 protein-DNA complex assembly IEA
 biological_processGO:0070365 hepatocyte differentiation IEA
 biological_processGO:0072095 regulation of branch elongation involved in ureteric bud branching IEA
 biological_processGO:0072181 mesonephric duct formation IEA
 biological_processGO:1900212 negative regulation of mesenchymal cell apoptotic process involved in metanephros development IEA
 cellular_componentGO:0005634 nucleus IDA
 cellular_componentGO:0005654 nucleoplasm IDA
 cellular_componentGO:0005667 transcription factor complex IEA
 molecular_functionGO:0000977 RNA polymerase II regulatory region sequence-specific DNA binding IBA
 molecular_functionGO:0000981 RNA polymerase II transcription factor activity, sequence-specific DNA binding ISA
 molecular_functionGO:0000987 proximal promoter sequence-specific DNA binding IEA
 molecular_functionGO:0003700 DNA-binding transcription factor activity IDA
 molecular_functionGO:0003705 transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0042803 protein homodimerization activity IEA
 molecular_functionGO:0044877 protein-containing complex binding IEA
 molecular_functionGO:0046982 protein heterodimerization activity IEA


Pathways (from Reactome)
Pathway description
No match


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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