6934


Homo sapiens (NCBI)

Features
Gene ID: 6934
  
Biological name :
  
Synonyms : TCF-4|TCF4 / TCF7L2 / transcription factor 7 like 2
  
Possible biological names infered from orthology :
  
Species: Homo sapiens (NCBI)
  
Chr. number:
Strand:
Band:
Gene start:
Gene end:
  
Corresponding Affymetrix probe sets: 212759_s_at (Human Genome U133 Plus 2.0 Array)   212761_at (Human Genome U133 Plus 2.0 Array)   212762_s_at (Human Genome U133 Plus 2.0 Array)   216035_x_at (Human Genome U133 Plus 2.0 Array)   216037_x_at (Human Genome U133 Plus 2.0 Array)   216511_s_at (Human Genome U133 Plus 2.0 Array)   236094_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: RefSeq - 530394227
RefSeq - 1034569354
RefSeq - 1034569356
RefSeq - 1034569358
RefSeq - 1034569360
RefSeq - 1034569362
RefSeq - 1034569364
RefSeq - 1034569366
RefSeq - 1034569368
RefSeq - 1034569370
RefSeq - 1034569372
RefSeq - 1034569377
RefSeq - 1034569380
RefSeq - 1169292921
RefSeq - 1169292923
RefSeq - 1370457717
RefSeq - 1391723646
RefSeq - 170014696
RefSeq - 226371620
RefSeq - 226371623
RefSeq - 226371625
RefSeq - 226371627
RefSeq - 226371764
RefSeq - 309384250
RefSeq - 309384252
RefSeq - 309384254
RefSeq - 309384257
RefSeq - 309384259
RefSeq - 309384261
RefSeq - 309384263
RefSeq - 530394185
RefSeq - 530394193
RefSeq - 530394197
RefSeq - 530394199
RefSeq - 530394201
RefSeq - 530394203
RefSeq - 530394211
RefSeq - 530394213
RefSeq - 530394215
RefSeq - 530394219
RefSeq - 530394221
RefSeq - 530394225
RefSeq - 1034569352
RefSeq - 530394229
RefSeq - 530394231
RefSeq - 530394233
RefSeq - 530394235
RefSeq - 530394243
RefSeq - 530394245
RefSeq - 530394247
RefSeq - 530394249
RefSeq - 530394251
RefSeq - 767963648
RefSeq - 767963650
RefSeq - 767963652
RefSeq - 767963663
RefSeq - NC_000010.11
RefSeq - NG_012631.1
RefSeq - NP_001139746.1
RefSeq - NP_001139755.1
RefSeq - NP_001139756.1
RefSeq - NP_001139757.1
RefSeq - NP_001139758.1
RefSeq - NP_001185454.1
RefSeq - NP_001185455.1
RefSeq - NP_001185456.1
RefSeq - NP_001185457.1
RefSeq - NP_001185458.1
RefSeq - NP_001185459.1
RefSeq - NP_001185460.1
RefSeq - NP_001336799.1
RefSeq - NP_001336800.1
RefSeq - NP_001350430.1
RefSeq - NP_110383.2
RefSeq - XP_005270128.1
RefSeq - XP_005270132.1
RefSeq - XP_005270134.1
RefSeq - XP_005270135.1
RefSeq - XP_005270136.1
RefSeq - XP_005270137.1
RefSeq - XP_005270141.1
RefSeq - XP_005270142.1
RefSeq - XP_005270143.1
RefSeq - XP_005270145.1
RefSeq - XP_005270146.1
RefSeq - XP_005270148.1
RefSeq - XP_005270149.1
RefSeq - XP_005270150.1
RefSeq - XP_005270151.1
RefSeq - XP_005270152.1
RefSeq - XP_005270153.1
RefSeq - XP_005270157.1
RefSeq - XP_005270158.1
RefSeq - XP_005270159.1
RefSeq - XP_005270160.1
RefSeq - XP_005270161.1
RefSeq - XP_011538411.1
RefSeq - XP_011538412.1
RefSeq - XP_011538413.1
RefSeq - XP_011538418.1
RefSeq - XP_016872073.1
RefSeq - XP_016872074.1
RefSeq - XP_016872075.1
RefSeq - XP_016872076.1
RefSeq - XP_016872077.1
RefSeq - XP_016872078.1
RefSeq - XP_016872079.1
RefSeq - XP_016872080.1
RefSeq - XP_016872081.1
RefSeq - XP_016872082.1
RefSeq - XP_016872083.1
RefSeq - XP_016872084.1
RefSeq - XP_016872085.1
RefSeq - XP_024303918.1
RefSeq - NM_001146274.1
RefSeq - NM_001146283.1
RefSeq - NM_001146284.1
RefSeq - NM_001146285.1
RefSeq - NM_001146286.1
RefSeq - NM_001198525.1
RefSeq - NM_001198526.1
RefSeq - NM_001198527.1
RefSeq - NM_001198528.1
RefSeq - NM_001198529.1
RefSeq - NM_001198530.1
RefSeq - NM_001198531.1
RefSeq - NM_001349870.1
RefSeq - NM_001349871.1
RefSeq - NM_001363501.1
RefSeq - NM_030756.4
RefSeq - XM_011540111.2
RefSeq - XM_011540116.2
RefSeq - XM_017016584.2
RefSeq - XM_017016585.2
RefSeq - XM_017016586.2
RefSeq - XM_017016587.2
RefSeq - XM_017016588.2
RefSeq - XM_017016589.2
RefSeq - XM_017016590.2
RefSeq - XM_017016591.2
RefSeq - XM_017016592.2
RefSeq - XM_017016593.2
RefSeq - XM_017016594.2
RefSeq - XM_017016595.2
RefSeq - XM_017016596.2
RefSeq - XM_024448150.1
RefSeq - XM_005270071.2
RefSeq - XM_005270075.2
RefSeq - XM_005270077.2
RefSeq - XM_005270078.2
RefSeq - XM_005270079.2
RefSeq - XM_005270080.2
RefSeq - XM_005270084.2
RefSeq - XM_005270085.2
RefSeq - XM_005270086.2
RefSeq - XM_005270088.2
RefSeq - XM_005270089.2
RefSeq - XM_005270091.3
RefSeq - XM_005270092.2
RefSeq - XM_005270093.3
RefSeq - XM_005270094.3
RefSeq - XM_005270095.2
RefSeq - XM_005270096.3
RefSeq - XM_005270100.2
RefSeq - XM_005270101.3
RefSeq - XM_005270102.2
RefSeq - XM_005270103.2
RefSeq - XM_005270104.2
RefSeq - XM_011540109.2
RefSeq - XM_011540110.2
  
See co-cited genes in PubMed
Warning: Please see the Ensembl gene model ENSG00000148737 to get all the annotations available for this gene.


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000122 negative regulation of transcription by RNA polymerase II IDA
 biological_processGO:0001568 blood vessel development IMP
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IBA
 biological_processGO:0006357 regulation of transcription by RNA polymerase II IDA
 biological_processGO:0007050 cell cycle arrest IMP
 biological_processGO:0007223 Wnt signaling pathway, calcium modulating pathway TAS
 biological_processGO:0008283 cell proliferation IMP
 biological_processGO:0009749 response to glucose ISS
 biological_processGO:0010909 positive regulation of heparan sulfate proteoglycan biosynthetic process IMP
 biological_processGO:0016055 Wnt signaling pathway IBA
 biological_processGO:0031016 pancreas development TAS
 biological_processGO:0032024 positive regulation of insulin secretion IMP
 biological_processGO:0032092 positive regulation of protein binding IDA
 biological_processGO:0032350 regulation of hormone metabolic process IDA
 biological_processGO:0042593 glucose homeostasis IDA
 biological_processGO:0043433 negative regulation of DNA-binding transcription factor activity IDA
 biological_processGO:0043570 maintenance of DNA repeat elements IMP
 biological_processGO:0044334 canonical Wnt signaling pathway involved in positive regulation of epithelial to mesenchymal transition IMP
 biological_processGO:0045444 fat cell differentiation IDA
 biological_processGO:0045892 negative regulation of transcription, DNA-templated IMP
 biological_processGO:0045944 positive regulation of transcription by RNA polymerase II IDA
 biological_processGO:0046827 positive regulation of protein export from nucleus IMP
 biological_processGO:0048625 myoblast fate commitment IDA
 biological_processGO:0048660 regulation of smooth muscle cell proliferation IMP
 biological_processGO:0051897 positive regulation of protein kinase B signaling IMP
 biological_processGO:0060070 canonical Wnt signaling pathway IC
 biological_processGO:0090090 negative regulation of canonical Wnt signaling pathway IMP
 biological_processGO:1904837 beta-catenin-TCF complex assembly TAS
 biological_processGO:2000675 negative regulation of type B pancreatic cell apoptotic process ISS
 biological_processGO:2001237 negative regulation of extrinsic apoptotic signaling pathway ISS
 cellular_componentGO:0000790 nuclear chromatin IDA
 cellular_componentGO:0005634 nucleus IDA
 cellular_componentGO:0005654 nucleoplasm TAS
 cellular_componentGO:0005667 transcription factor complex IBA
 cellular_componentGO:0016605 PML body IEA
 cellular_componentGO:0032993 protein-DNA complex IDA
 cellular_componentGO:0070369 beta-catenin-TCF7L2 complex IDA
 molecular_functionGO:0000978 RNA polymerase II proximal promoter sequence-specific DNA binding IDA
 molecular_functionGO:0000981 RNA polymerase II transcription factor activity, sequence-specific DNA binding NAS
 molecular_functionGO:0001103 RNA polymerase II repressing transcription factor binding IPI
 molecular_functionGO:0003682 chromatin binding IBA
 molecular_functionGO:0003700 DNA-binding transcription factor activity IDA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0008013 beta-catenin binding IPI
 molecular_functionGO:0008134 transcription factor binding IPI
 molecular_functionGO:0019901 protein kinase binding IPI
 molecular_functionGO:0035257 nuclear hormone receptor binding IPI
 molecular_functionGO:0043565 sequence-specific DNA binding IMP
 molecular_functionGO:0044212 transcription regulatory region DNA binding IDA
 molecular_functionGO:0045295 gamma-catenin binding IPI
 molecular_functionGO:0070016 armadillo repeat domain binding IPI


Pathways (from Reactome)
Pathway description
No match


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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