7015


Homo sapiens (NCBI)

Features
Gene ID: 7015
  
Biological name :
  
Synonyms : CMM9|DKCA2|DKCB4|EST2|PFBMFT1|TCS1|TP2|TRT|hEST2|hTRT / telomerase reverse transcriptase / TERT
  
Possible biological names infered from orthology :
  
Species: Homo sapiens (NCBI)
  
Chr. number:
Strand:
Band:
Gene start:
Gene end:
  
Corresponding Affymetrix probe sets: 1555271_a_at (Human Genome U133 Plus 2.0 Array)   207199_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: RefSeq - NG_009265.1
RefSeq - 301129200
RefSeq - NP_001180305.1
RefSeq - NP_937983.2
RefSeq - NC_000005.10
RefSeq - 109633031
RefSeq - NR_149163.1
RefSeq - NM_001193376.1
RefSeq - NM_198253.2
RefSeq - NM_198254.1
RefSeq - NM_198255.2
RefSeq - NR_149162.1
  
See co-cited genes in PubMed
Warning: Please see the Ensembl gene model ENSG00000164362 to get all the annotations available for this gene.


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000723 telomere maintenance TAS
 biological_processGO:0001172 transcription, RNA-templated IDA
 biological_processGO:0006278 RNA-dependent DNA biosynthetic process IDA
 biological_processGO:0007004 telomere maintenance via telomerase TAS
 biological_processGO:0007005 mitochondrion organization IDA
 biological_processGO:0010629 negative regulation of gene expression IDA
 biological_processGO:0022616 DNA strand elongation IDA
 biological_processGO:0030177 positive regulation of Wnt signaling pathway IGI
 biological_processGO:0030422 production of siRNA involved in RNA interference IDA
 biological_processGO:0031647 regulation of protein stability IMP
 biological_processGO:0032092 positive regulation of protein binding IDA
 biological_processGO:0032774 RNA biosynthetic process IDA
 biological_processGO:0042635 positive regulation of hair cycle ISS
 biological_processGO:0043524 negative regulation of neuron apoptotic process IEA
 biological_processGO:0045766 positive regulation of angiogenesis IEA
 biological_processGO:0046326 positive regulation of glucose import IEA
 biological_processGO:0046686 response to cadmium ion IEA
 biological_processGO:0051000 positive regulation of nitric-oxide synthase activity IDA
 biological_processGO:0060253 negative regulation of glial cell proliferation IEA
 biological_processGO:0070200 establishment of protein localization to telomere IDA
 biological_processGO:0071456 cellular response to hypoxia IMP
 biological_processGO:0071897 DNA biosynthetic process IDA
 biological_processGO:0090399 replicative senescence IMP
 biological_processGO:1900087 positive regulation of G1/S transition of mitotic cell cycle IEA
 biological_processGO:1902895 positive regulation of pri-miRNA transcription by RNA polymerase II IMP
 biological_processGO:1903620 positive regulation of transdifferentiation IEA
 biological_processGO:1903704 negative regulation of production of siRNA involved in RNA interference IDA
 biological_processGO:1904707 positive regulation of vascular smooth muscle cell proliferation IEA
 biological_processGO:1904751 positive regulation of protein localization to nucleolus IDA
 biological_processGO:1904754 positive regulation of vascular associated smooth muscle cell migration IEA
 biological_processGO:1904837 beta-catenin-TCF complex assembly TAS
 biological_processGO:2000352 negative regulation of endothelial cell apoptotic process IEA
 biological_processGO:2000648 positive regulation of stem cell proliferation ISS
 biological_processGO:2000773 negative regulation of cellular senescence IMP
 biological_processGO:2001240 negative regulation of extrinsic apoptotic signaling pathway in absence of ligand IMP
 cellular_componentGO:0000333 telomerase catalytic core complex IPI
 cellular_componentGO:0000781 chromosome, telomeric region IC
 cellular_componentGO:0000783 nuclear telomere cap complex IC
 cellular_componentGO:0000784 nuclear chromosome, telomeric region IDA
 cellular_componentGO:0005634 nucleus IDA
 cellular_componentGO:0005654 nucleoplasm TAS
 cellular_componentGO:0005697 telomerase holoenzyme complex TAS
 cellular_componentGO:0005730 nucleolus NAS
 cellular_componentGO:0005829 cytosol IDA
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0016605 PML body IDA
 cellular_componentGO:0016607 nuclear speck IDA
 cellular_componentGO:0031379 RNA-directed RNA polymerase complex IPI
 cellular_componentGO:0042645 mitochondrial nucleoid IDA
 cellular_componentGO:1990572 TERT-RMRP complex IDA
 molecular_functionGO:0000049 tRNA binding IDA
 molecular_functionGO:0001223 transcription coactivator binding IPI
 molecular_functionGO:0003677 DNA binding IDA
 molecular_functionGO:0003720 telomerase activity TAS
 molecular_functionGO:0003721 telomerase RNA reverse transcriptase activity TAS
 molecular_functionGO:0003723 RNA binding IPI
 molecular_functionGO:0003964 RNA-directed DNA polymerase activity TAS
 molecular_functionGO:0003968 RNA-directed 5"-3" RNA polymerase activity IDA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0008022 protein C-terminus binding IPI
 molecular_functionGO:0016779 nucleotidyltransferase activity IDA
 molecular_functionGO:0042162 telomeric DNA binding TAS
 molecular_functionGO:0042802 identical protein binding IPI
 molecular_functionGO:0042803 protein homodimerization activity IPI
 molecular_functionGO:0046872 metal ion binding IEA
 molecular_functionGO:0047485 protein N-terminus binding IPI
 molecular_functionGO:0051087 chaperone binding IPI
 molecular_functionGO:0070034 telomerase RNA binding IPI
 molecular_functionGO:0098680 template-free RNA nucleotidyltransferase IDA


Pathways (from Reactome)
Pathway description
No match


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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