7048


Homo sapiens (NCBI)

Features
Gene ID: 7048
  
Biological name :
  
Synonyms : AAT3|FAA3|LDS1B|LDS2|LDS2B|MFS2|RIIC|TAAD2|TBR-ii|TBRII|TGFR-2|TGFbeta-RII / TGFBR2 / transforming growth factor beta receptor 2
  
Possible biological names infered from orthology :
  
Species: Homo sapiens (NCBI)
  
Chr. number:
Strand:
Band:
Gene start:
Gene end:
  
Corresponding Affymetrix probe sets: 207334_s_at (Human Genome U133 Plus 2.0 Array)   208944_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: RefSeq - 1034635280
RefSeq - 67782324
RefSeq - 67782326
RefSeq - 767924117
RefSeq - 767924121
RefSeq - NC_000003.12
RefSeq - NG_007490.1
RefSeq - NP_001020018.1
RefSeq - NP_003233.4
RefSeq - XP_011532345.1
RefSeq - XP_011532347.1
RefSeq - XP_016862595.1
RefSeq - NM_001024847.2
RefSeq - NM_003242.5
RefSeq - XM_011534045.3
RefSeq - XM_017007106.1
RefSeq - XM_011534043.2
  
See co-cited genes in PubMed
Warning: Please see the Ensembl gene model ENSG00000163513 to get all the annotations available for this gene.


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001568 blood vessel development TAS
 biological_processGO:0001569 branching involved in blood vessel morphogenesis ISS
 biological_processGO:0001570 vasculogenesis ISS
 biological_processGO:0001666 response to hypoxia IEA
 biological_processGO:0001701 in utero embryonic development IEA
 biological_processGO:0001947 heart looping ISS
 biological_processGO:0002053 positive regulation of mesenchymal cell proliferation ISS
 biological_processGO:0002088 lens development in camera-type eye IEA
 biological_processGO:0002651 positive regulation of tolerance induction to self antigen ISS
 biological_processGO:0002663 positive regulation of B cell tolerance induction ISS
 biological_processGO:0002666 positive regulation of T cell tolerance induction ISS
 biological_processGO:0003148 outflow tract septum morphogenesis ISS
 biological_processGO:0003149 membranous septum morphogenesis ISS
 biological_processGO:0003151 outflow tract morphogenesis ISS
 biological_processGO:0003181 atrioventricular valve morphogenesis ISS
 biological_processGO:0003186 tricuspid valve morphogenesis ISS
 biological_processGO:0003214 cardiac left ventricle morphogenesis ISS
 biological_processGO:0003274 endocardial cushion fusion ISS
 biological_processGO:0003430 growth plate cartilage chondrocyte growth IEA
 biological_processGO:0006468 protein phosphorylation IDA
 biological_processGO:0006898 receptor-mediated endocytosis IEA
 biological_processGO:0006915 apoptotic process IDA
 biological_processGO:0007179 transforming growth factor beta receptor signaling pathway TAS
 biological_processGO:0007182 common-partner SMAD protein phosphorylation IEA
 biological_processGO:0007219 Notch signaling pathway IEA
 biological_processGO:0007224 smoothened signaling pathway IEA
 biological_processGO:0007369 gastrulation IEA
 biological_processGO:0007389 pattern specification process IBA
 biological_processGO:0007420 brain development ISS
 biological_processGO:0007507 heart development ISS
 biological_processGO:0007566 embryo implantation IEA
 biological_processGO:0007568 aging IEA
 biological_processGO:0007584 response to nutrient IEA
 biological_processGO:0008284 positive regulation of cell proliferation TAS
 biological_processGO:0009612 response to mechanical stimulus IEA
 biological_processGO:0009749 response to glucose IEA
 biological_processGO:0010468 regulation of gene expression IEA
 biological_processGO:0010634 positive regulation of epithelial cell migration IEA
 biological_processGO:0010718 positive regulation of epithelial to mesenchymal transition IDA
 biological_processGO:0018105 peptidyl-serine phosphorylation IDA
 biological_processGO:0018107 peptidyl-threonine phosphorylation IDA
 biological_processGO:0030512 negative regulation of transforming growth factor beta receptor signaling pathway TAS
 biological_processGO:0031100 animal organ regeneration IEA
 biological_processGO:0032147 activation of protein kinase activity ISS
 biological_processGO:0032924 activin receptor signaling pathway IBA
 biological_processGO:0035162 embryonic hemopoiesis ISS
 biological_processGO:0042060 wound healing IEA
 biological_processGO:0042127 regulation of cell proliferation ISS
 biological_processGO:0042493 response to drug IDA
 biological_processGO:0043011 myeloid dendritic cell differentiation ISS
 biological_processGO:0043415 positive regulation of skeletal muscle tissue regeneration IEA
 biological_processGO:0043627 response to estrogen IEA
 biological_processGO:0045766 positive regulation of angiogenesis IEA
 biological_processGO:0048545 response to steroid hormone IEA
 biological_processGO:0048565 digestive tract development IEA
 biological_processGO:0048661 positive regulation of smooth muscle cell proliferation IEA
 biological_processGO:0048701 embryonic cranial skeleton morphogenesis ISS
 biological_processGO:0051138 positive regulation of NK T cell differentiation ISS
 biological_processGO:0060044 negative regulation of cardiac muscle cell proliferation IEA
 biological_processGO:0060389 pathway-restricted SMAD protein phosphorylation IDA
 biological_processGO:0060412 ventricular septum morphogenesis ISS
 biological_processGO:0060434 bronchus morphogenesis IEA
 biological_processGO:0060440 trachea formation IEA
 biological_processGO:0060443 mammary gland morphogenesis IEA
 biological_processGO:0060463 lung lobe morphogenesis IEA
 biological_processGO:0062009 secondary palate development ISS
 biological_processGO:0070723 response to cholesterol IDA
 biological_processGO:1905007 positive regulation of epithelial to mesenchymal transition involved in endocardial cushion formation ISS
 biological_processGO:1905315 cell proliferation involved in endocardial cushion morphogenesis ISS
 biological_processGO:1905316 superior endocardial cushion morphogenesis ISS
 biological_processGO:1905317 inferior endocardial cushion morphogenesis ISS
 biological_processGO:1990086 lens fiber cell apoptotic process IEA
 biological_processGO:1990428 miRNA transport ISS
 biological_processGO:2000379 positive regulation of reactive oxygen species metabolic process IMP
 biological_processGO:2000563 positive regulation of CD4-positive, alpha-beta T cell proliferation IDA
 cellular_componentGO:0005829 cytosol TAS
 cellular_componentGO:0005886 plasma membrane TAS
 cellular_componentGO:0005887 integral component of plasma membrane IBA
 cellular_componentGO:0005901 caveola IDA
 cellular_componentGO:0009897 external side of plasma membrane IDA
 cellular_componentGO:0016021 integral component of membrane IDA
 cellular_componentGO:0043235 receptor complex IDA
 cellular_componentGO:0045121 membrane raft IDA
 cellular_componentGO:0048179 activin receptor complex IBA
 cellular_componentGO:0070022 transforming growth factor beta receptor complex IC
 molecular_functionGO:0004675 transmembrane receptor protein serine/threonine kinase activity IDA
 molecular_functionGO:0005024 transforming growth factor beta-activated receptor activity IMP
 molecular_functionGO:0005026 transforming growth factor beta receptor activity, type II IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0005539 glycosaminoglycan binding IDA
 molecular_functionGO:0019838 growth factor binding IBA
 molecular_functionGO:0031435 mitogen-activated protein kinase kinase kinase binding IEA
 molecular_functionGO:0034713 type I transforming growth factor beta receptor binding IPI
 molecular_functionGO:0046332 SMAD binding IDA
 molecular_functionGO:0046872 metal ion binding IEA
 molecular_functionGO:0048185 activin binding IBA
 molecular_functionGO:0050431 transforming growth factor beta binding IPI


Pathways (from Reactome)
Pathway description
No match


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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