7075


Homo sapiens (NCBI)
kinaseregulationactivityproteindevelopmentreceptorbindingangiogenesissignaltransductioncellcascadeplasmamembraneerktyrosinetransmembranevasculogenesisuteroembryonicmulticellularorganismmesodermpeptidyl-tyrosinephosphorylationdifferentiationmigrationresponseretinoicacid

Features
Gene ID: 7075
  
Biological name :
  
Synonyms : JTK14|TIE / TIE1 / tyrosine kinase with immunoglobulin like and EGF like domains 1
  
Possible biological names infered from orthology :
  
Species: Homo sapiens (NCBI)
  
Chr. number:
Strand:
Band:
Gene start:
Gene end:
  
Corresponding Affymetrix probe sets: 1560657_at (Human Genome U133 Plus 2.0 Array)   204468_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: RefSeq - 1034561462
RefSeq - 358356428
RefSeq - 4885631
RefSeq - 530363246
RefSeq - 578799696
RefSeq - NC_000001.11
RefSeq - NG_030673.1
RefSeq - NP_001240286.1
RefSeq - NP_005415.1
RefSeq - XP_005271220.1
RefSeq - XP_006710932.1
RefSeq - XP_016857696.1
RefSeq - XM_006710869.1
RefSeq - NM_001253357.1
RefSeq - NM_005424.4
RefSeq - XM_017002207.2
RefSeq - XR_946751.2
RefSeq - XM_005271163.2
  
See co-cited genes in PubMed
Warning: Please see the Ensembl gene model ENSG00000066056 to get all the annotations available for this gene.


Gene Ontology (GO)
anatomical structure developmentcellular developmental processcell communicationcellular response to stimulusnitrogen compound metabolic processcellular metabolic processprimary metabolic processorganic substance metabolic processlocalization of cellmovement of cell or subcellular componentresponse to chemicalregulation of molecular functioncell deathcellular component organizationanatomical structure developmentcellular developmental processcell communicationcellular response to stimulusnitrogen compound metabolic processcellular metabolic processprimary metabolic processorganic substance metabolic processlocalization of cellmovement of cell or subcellular componentresponse to chemicalregulation of molecular functioncell deathcellular component organizationanatomical structure developmentcellular developmental processcell communicationcellular response to stimulusnitrogen compound metabolic processcellular metabolic processprimary metabolic processorganic substance metabolic processlocalization of cellmovement of cell or subcellular componentresponse to chemicalregulation of molecular functioncell deathcellular component organizationanatomical structure developmentcellular developmental processcell communicationcellular response to stimulusnitrogen compound metabolic processcellular metabolic processprimary metabolic processorganic substance metabolic processlocalization of cellmovement of cell or subcellular componentresponse to chemicalregulation of molecular functioncell deathcellular component organizationanatomical structure developmentcellular developmental processcell communicationcellular response to stimulusnitrogen compound metabolic processcellular metabolic processprimary metabolic processorganic substance metabolic processlocalization of cellmovement of cell or subcellular componentresponse to chemicalregulation of molecular functioncell deathcellular component organizationanatomical structure developmentcellular developmental processcell communicationcellular response to stimulusnitrogen compound metabolic processcellular metabolic processprimary metabolic processorganic substance metabolic processlocalization of cellmovement of cell or subcellular componentresponse to chemicalregulation of molecular functioncell deathcellular component organizationanatomical structure developmentcellular developmental processcell communicationcellular response to stimulusnitrogen compound metabolic processcellular metabolic processprimary metabolic processorganic substance metabolic processlocalization of cellmovement of cell or subcellular componentresponse to chemicalregulation of molecular functioncell deathcellular component organizationanatomical structure developmentcellular developmental processcell communicationcellular response to stimulusnitrogen compound metabolic processcellular metabolic processprimary metabolic processorganic substance metabolic processlocalization of cellmovement of cell or subcellular componentresponse to chemicalregulation of molecular functioncell deathcellular component organizationanatomical structure developmentcellular developmental processcell communicationcellular response to stimulusnitrogen compound metabolic processcellular metabolic processprimary metabolic processorganic substance metabolic processlocalization of cellmovement of cell or subcellular componentresponse to chemicalregulation of molecular functioncell deathcellular component organizationanatomical structure developmentcellular developmental processcell communicationcellular response to stimulusnitrogen compound metabolic processcellular metabolic processprimary metabolic processorganic substance metabolic processlocalization of cellmovement of cell or subcellular componentresponse to chemicalregulation of molecular functioncell deathcellular component organizationanatomicalanatomical structure developmentcellular dcellular developmental processcell commucell communicationcellular rcellular response to stimulusnitrogen cnitrogen compound metabolic processcellular mcellular metabolic processprimary meprimary metabolic processorganic suorganic substance metabolic processlocalizatilocalization of cellmovement omovement of cell or subcellular componentresponse tresponse to chemicalregulationregulation of molecular functioncell deathcell deathcellular ccellular component organization
catalytic activity, acting on a proteintransferase activitysignaling receptor activityprotein bindingion bindingcarbohydrate derivative bindingorganic cyclic compound bindingheterocyclic compound bindingsmall molecule bindingdrug bindingcatalytic activity, acting on a proteintransferase activitysignaling receptor activityprotein bindingion bindingcarbohydrate derivative bindingorganic cyclic compound bindingheterocyclic compound bindingsmall molecule bindingdrug bindingcatalytic activity, acting on a proteintransferase activitysignaling receptor activityprotein bindingion bindingcarbohydrate derivative bindingorganic cyclic compound bindingheterocyclic compound bindingsmall molecule bindingdrug bindingcatalytic activity, acting on a proteintransferase activitysignaling receptor activityprotein bindingion bindingcarbohydrate derivative bindingorganic cyclic compound bindingheterocyclic compound bindingsmall molecule bindingdrug bindingcatalytic activity, acting on a proteintransferase activitysignaling receptor activityprotein bindingion bindingcarbohydrate derivative bindingorganic cyclic compound bindingheterocyclic compound bindingsmall molecule bindingdrug bindingcatalytic activity, acting on a proteintransferase activitysignaling receptor activityprotein bindingion bindingcarbohydrate derivative bindingorganic cyclic compound bindingheterocyclic compound bindingsmall molecule bindingdrug bindingcatalytic activity, acting on a proteintransferase activitysignaling receptor activityprotein bindingion bindingcarbohydrate derivative bindingorganic cyclic compound bindingheterocyclic compound bindingsmall molecule bindingdrug bindingcatalytic activity, acting on a proteintransferase activitysignaling receptor activityprotein bindingion bindingcarbohydrate derivative bindingorganic cyclic compound bindingheterocyclic compound bindingsmall molecule bindingdrug bindingcatalytic activity, acting on a proteintransferase activitysignaling receptor activityprotein bindingion bindingcarbohydrate derivative bindingorganic cyclic compound bindingheterocyclic compound bindingsmall molecule bindingdrug bindingcatalytic activity, acting on a proteintransferase activitysignaling receptor activityprotein bindingion bindingcarbohydrate derivative bindingorganic cyclic compound bindingheterocyclic compound bindingsmall molecule bindingdrug bindingcatalytic acticatalytic activity, acting on a proteintransferase actransferase activitysignaling recesignaling receptor activityprotein bindinprotein bindingion bindingion bindingcarbohydrate dcarbohydrate derivative bindingorganic cyclicorganic cyclic compound bindingheterocyclic cheterocyclic compound bindingsmall moleculesmall molecule bindingdrug bindingdrug binding
cellmembraneprotein-containing complexcellmembraneprotein-containing complexcellmembraneprotein-containing complexcellmembraneprotein-containing complexcellmembraneprotein-containing complexcellmembraneprotein-containing complexcellmembraneprotein-containing complexcellmembraneprotein-containing complexcellmembraneprotein-containing complexcellmembraneprotein-containing complexcellcellmembranemembraneprotein-containing complexprotein-containing complex
TypeGO IDTermEv.Code
 biological_processGO:0001525 angiogenesis IEA
 biological_processGO:0001570 vasculogenesis IEA
 biological_processGO:0001701 in utero embryonic development IEA
 biological_processGO:0007165 signal transduction TAS
 biological_processGO:0007275 multicellular organism development IBA
 biological_processGO:0007498 mesoderm development TAS
 biological_processGO:0009968 negative regulation of signal transduction IBA
 biological_processGO:0016525 negative regulation of angiogenesis IEA
 biological_processGO:0018108 peptidyl-tyrosine phosphorylation IEA
 biological_processGO:0030154 cell differentiation IBA
 biological_processGO:0030336 negative regulation of cell migration IEA
 biological_processGO:0032526 response to retinoic acid IEA
 biological_processGO:0033674 positive regulation of kinase activity IBA
 biological_processGO:0043066 negative regulation of apoptotic process IBA
 biological_processGO:0043410 positive regulation of MAPK cascade IBA
 biological_processGO:0045026 plasma membrane fusion IEA
 biological_processGO:0070374 positive regulation of ERK1 and ERK2 cascade IBA
 cellular_componentGO:0005737 cytoplasm IBA
 cellular_componentGO:0005887 integral component of plasma membrane TAS
 cellular_componentGO:0043235 receptor complex IBA
 molecular_functionGO:0004709 MAP kinase kinase kinase activity IBA
 molecular_functionGO:0004713 protein tyrosine kinase activity IBA
 molecular_functionGO:0004714 transmembrane receptor protein tyrosine kinase activity IEA
 molecular_functionGO:0004888 transmembrane signaling receptor activity IBA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0031434 mitogen-activated protein kinase kinase binding IBA


Pathways (from Reactome)
Pathway description
No match


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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