7098


Homo sapiens (NCBI)

Features
Gene ID: 7098
  
Biological name :
  
Synonyms : CD283|IIAE2 / TLR3 / toll like receptor 3
  
Possible biological names infered from orthology :
  
Species: Homo sapiens (NCBI)
  
Chr. number:
Strand:
Band:
Gene start:
Gene end:
  
Corresponding Affymetrix probe sets: 206271_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: RefSeq - 4507531
RefSeq - NC_000004.12
RefSeq - NG_007278.1
RefSeq - NP_003256.1
RefSeq - NM_003265.2
  
See co-cited genes in PubMed
Warning: Please see the Ensembl gene model ENSG00000164342 to get all the annotations available for this gene.


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001774 microglial cell activation IEA
 biological_processGO:0002224 toll-like receptor signaling pathway TAS
 biological_processGO:0002730 regulation of dendritic cell cytokine production IEA
 biological_processGO:0002756 MyD88-independent toll-like receptor signaling pathway TAS
 biological_processGO:0006954 inflammatory response IEA
 biological_processGO:0006972 hyperosmotic response NAS
 biological_processGO:0007165 signal transduction TAS
 biological_processGO:0007249 I-kappaB kinase/NF-kappaB signaling TAS
 biological_processGO:0007250 activation of NF-kappaB-inducing kinase activity NAS
 biological_processGO:0007252 I-kappaB phosphorylation IDA
 biological_processGO:0008584 male gonad development IEA
 biological_processGO:0009597 detection of virus NAS
 biological_processGO:0010628 positive regulation of gene expression IMP
 biological_processGO:0032722 positive regulation of chemokine production IDA
 biological_processGO:0032728 positive regulation of interferon-beta production ISS
 biological_processGO:0032735 positive regulation of interleukin-12 production ISS
 biological_processGO:0032755 positive regulation of interleukin-6 production IDA
 biological_processGO:0032757 positive regulation of interleukin-8 production IDA
 biological_processGO:0032760 positive regulation of tumor necrosis factor production ISS
 biological_processGO:0034123 positive regulation of toll-like receptor signaling pathway IDA
 biological_processGO:0034128 negative regulation of MyD88-independent toll-like receptor signaling pathway TAS
 biological_processGO:0034138 toll-like receptor 3 signaling pathway TAS
 biological_processGO:0034346 positive regulation of type III interferon production IEA
 biological_processGO:0035458 cellular response to interferon-beta IEA
 biological_processGO:0035666 TRIF-dependent toll-like receptor signaling pathway TAS
 biological_processGO:0035690 cellular response to drug IEA
 biological_processGO:0042742 defense response to bacterium TAS
 biological_processGO:0043065 positive regulation of apoptotic process IEA
 biological_processGO:0043123 positive regulation of I-kappaB kinase/NF-kappaB signaling IEA
 biological_processGO:0043330 response to exogenous dsRNA IDA
 biological_processGO:0043331 response to dsRNA IBA
 biological_processGO:0045078 positive regulation of interferon-gamma biosynthetic process IDA
 biological_processGO:0045080 positive regulation of chemokine biosynthetic process IEA
 biological_processGO:0045087 innate immune response TAS
 biological_processGO:0045356 positive regulation of interferon-alpha biosynthetic process IDA
 biological_processGO:0045359 positive regulation of interferon-beta biosynthetic process IMP
 biological_processGO:0045671 negative regulation of osteoclast differentiation NAS
 biological_processGO:0045766 positive regulation of angiogenesis IEA
 biological_processGO:0045944 positive regulation of transcription by RNA polymerase II ISS
 biological_processGO:0046330 positive regulation of JNK cascade IEA
 biological_processGO:0050729 positive regulation of inflammatory response IC
 biological_processGO:0051092 positive regulation of NF-kappaB transcription factor activity IEA
 biological_processGO:0051607 defense response to virus TAS
 biological_processGO:0070266 necroptotic process TAS
 biological_processGO:0071260 cellular response to mechanical stimulus IEP
 biological_processGO:0071346 cellular response to interferon-gamma IEA
 biological_processGO:0071360 cellular response to exogenous dsRNA IEA
 biological_processGO:0097190 apoptotic signaling pathway TAS
 biological_processGO:0097191 extrinsic apoptotic signaling pathway IDA
 biological_processGO:0097527 necroptotic signaling pathway IDA
 biological_processGO:1901224 positive regulation of NIK/NF-kappaB signaling IDA
 cellular_componentGO:0000139 Golgi membrane TAS
 cellular_componentGO:0005622 intracellular IDA
 cellular_componentGO:0005737 cytoplasm IDA
 cellular_componentGO:0005765 lysosomal membrane HDA
 cellular_componentGO:0005769 early endosome IEA
 cellular_componentGO:0005789 endoplasmic reticulum membrane TAS
 cellular_componentGO:0005887 integral component of plasma membrane TAS
 cellular_componentGO:0009986 cell surface IDA
 cellular_componentGO:0010008 endosome membrane TAS
 cellular_componentGO:0016020 membrane NAS
 cellular_componentGO:0036020 endolysosome membrane TAS
 molecular_functionGO:0003725 double-stranded RNA binding NAS
 molecular_functionGO:0004888 transmembrane signaling receptor activity NAS
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0038023 signaling receptor activity TAS
 molecular_functionGO:0042802 identical protein binding IPI


Pathways (from Reactome)
Pathway description
No match


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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