7099


Homo sapiens (NCBI)

Features
Gene ID: 7099
  
Biological name :
  
Synonyms : ARMD10|CD284|TLR-4|TOLL / TLR4 / toll like receptor 4
  
Possible biological names infered from orthology :
  
Species: Homo sapiens (NCBI)
  
Chr. number:
Strand:
Band:
Gene start:
Gene end:
  
Corresponding Affymetrix probe sets: 1552798_a_at (Human Genome U133 Plus 2.0 Array)   221060_s_at (Human Genome U133 Plus 2.0 Array)   224341_x_at (Human Genome U133 Plus 2.0 Array)   232068_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: RefSeq - 19924149
RefSeq - 19924153
RefSeq - 4507533
RefSeq - NC_000009.12
RefSeq - NG_011475.1
RefSeq - NP_003257.1
RefSeq - NP_612564.1
RefSeq - NP_612567.1
RefSeq - NM_138557.2
RefSeq - NM_003266.3
RefSeq - NM_138554.4
RefSeq - NM_138556.1
  
See co-cited genes in PubMed
Warning: Please see the Ensembl gene model ENSG00000136869 to get all the annotations available for this gene.


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000187 activation of MAPK activity ISS
 biological_processGO:0002224 toll-like receptor signaling pathway TAS
 biological_processGO:0002755 MyD88-dependent toll-like receptor signaling pathway TAS
 biological_processGO:0002756 MyD88-independent toll-like receptor signaling pathway TAS
 biological_processGO:0006954 inflammatory response IBA
 biological_processGO:0006955 immune response TAS
 biological_processGO:0007249 I-kappaB kinase/NF-kappaB signaling TAS
 biological_processGO:0007252 I-kappaB phosphorylation IDA
 biological_processGO:0010572 positive regulation of platelet activation ISS
 biological_processGO:0010628 positive regulation of gene expression ISS
 biological_processGO:0016046 detection of fungus NAS
 biological_processGO:0031663 lipopolysaccharide-mediated signaling pathway IGI
 biological_processGO:0032496 response to lipopolysaccharide IDA
 biological_processGO:0032497 detection of lipopolysaccharide IDA
 biological_processGO:0032689 negative regulation of interferon-gamma production ISS
 biological_processGO:0032700 negative regulation of interleukin-17 production ISS
 biological_processGO:0032707 negative regulation of interleukin-23 production ISS
 biological_processGO:0032715 negative regulation of interleukin-6 production ISS
 biological_processGO:0032720 negative regulation of tumor necrosis factor production ISS
 biological_processGO:0032722 positive regulation of chemokine production IDA
 biological_processGO:0032727 positive regulation of interferon-alpha production ISS
 biological_processGO:0032728 positive regulation of interferon-beta production ISS
 biological_processGO:0032729 positive regulation of interferon-gamma production ISS
 biological_processGO:0032732 positive regulation of interleukin-1 production ISS
 biological_processGO:0032733 positive regulation of interleukin-10 production ISS
 biological_processGO:0032735 positive regulation of interleukin-12 production ISS
 biological_processGO:0032755 positive regulation of interleukin-6 production IDA
 biological_processGO:0032757 positive regulation of interleukin-8 production IDA
 biological_processGO:0032760 positive regulation of tumor necrosis factor production ISS
 biological_processGO:0034128 negative regulation of MyD88-independent toll-like receptor signaling pathway TAS
 biological_processGO:0034142 toll-like receptor 4 signaling pathway TAS
 biological_processGO:0035666 TRIF-dependent toll-like receptor signaling pathway TAS
 biological_processGO:0042088 T-helper 1 type immune response NAS
 biological_processGO:0042116 macrophage activation IMP
 biological_processGO:0042535 positive regulation of tumor necrosis factor biosynthetic process IDA
 biological_processGO:0042742 defense response to bacterium TAS
 biological_processGO:0043032 positive regulation of macrophage activation ISS
 biological_processGO:0045084 positive regulation of interleukin-12 biosynthetic process IDA
 biological_processGO:0045087 innate immune response TAS
 biological_processGO:0045416 positive regulation of interleukin-8 biosynthetic process IDA
 biological_processGO:0045429 positive regulation of nitric oxide biosynthetic process ISS
 biological_processGO:0045671 negative regulation of osteoclast differentiation NAS
 biological_processGO:0045944 positive regulation of transcription by RNA polymerase II ISS
 biological_processGO:0050702 interleukin-1 beta secretion ISS
 biological_processGO:0050718 positive regulation of interleukin-1 beta secretion IDA
 biological_processGO:0050729 positive regulation of inflammatory response IC
 biological_processGO:0050829 defense response to Gram-negative bacterium IC
 biological_processGO:0051092 positive regulation of NF-kappaB transcription factor activity IGI
 biological_processGO:0051770 positive regulation of nitric-oxide synthase biosynthetic process ISS
 biological_processGO:0060729 intestinal epithelial structure maintenance ISS
 biological_processGO:0070266 necroptotic process TAS
 biological_processGO:0070373 negative regulation of ERK1 and ERK2 cascade ISS
 biological_processGO:0071222 cellular response to lipopolysaccharide ISS
 biological_processGO:0071260 cellular response to mechanical stimulus IEP
 biological_processGO:0071346 cellular response to interferon-gamma IDA
 biological_processGO:0097190 apoptotic signaling pathway TAS
 biological_processGO:0140052 cellular response to oxidised low-density lipoprotein particle stimulus ISS
 biological_processGO:1900017 positive regulation of cytokine production involved in inflammatory response ISS
 biological_processGO:1900227 positive regulation of NLRP3 inflammasome complex assembly ISS
 biological_processGO:1901224 positive regulation of NIK/NF-kappaB signaling IDA
 biological_processGO:1903223 positive regulation of oxidative stress-induced neuron death ISS
 biological_processGO:1903428 positive regulation of reactive oxygen species biosynthetic process ISS
 biological_processGO:1903974 positive regulation of cellular response to macrophage colony-stimulating factor stimulus IDA
 biological_processGO:1904646 cellular response to amyloid-beta IGI
 cellular_componentGO:0005622 intracellular IPI
 cellular_componentGO:0005737 cytoplasm IDA
 cellular_componentGO:0005769 early endosome IEA
 cellular_componentGO:0005886 plasma membrane TAS
 cellular_componentGO:0005887 integral component of plasma membrane IDA
 cellular_componentGO:0009897 external side of plasma membrane IDA
 cellular_componentGO:0009986 cell surface IDA
 cellular_componentGO:0010008 endosome membrane TAS
 cellular_componentGO:0031226 intrinsic component of plasma membrane IDA
 cellular_componentGO:0043235 receptor complex IPI
 cellular_componentGO:0046696 lipopolysaccharide receptor complex IDA
 cellular_componentGO:0048471 perinuclear region of cytoplasm IDA
 molecular_functionGO:0001530 lipopolysaccharide binding NAS
 molecular_functionGO:0001875 lipopolysaccharide receptor activity IDA
 molecular_functionGO:0004888 transmembrane signaling receptor activity NAS
 molecular_functionGO:0005102 signaling receptor binding IPI
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0038023 signaling receptor activity TAS
 molecular_functionGO:0042802 identical protein binding IPI
 molecular_functionGO:0046982 protein heterodimerization activity IPI


Pathways (from Reactome)
Pathway description
No match


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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