7150


Homo sapiens (NCBI)

Features
Gene ID: 7150
  
Biological name :
  
Synonyms : DNA topoisomerase I / TOP1 / TOPI
  
Possible biological names infered from orthology :
  
Species: Homo sapiens (NCBI)
  
Chr. number:
Strand:
Band:
Gene start:
Gene end:
  
Corresponding Affymetrix probe sets: 208900_s_at (Human Genome U133 Plus 2.0 Array)   208901_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: RefSeq - 11225260
RefSeq - NC_000020.11
RefSeq - NG_012262.1
RefSeq - NP_003277.1
RefSeq - NM_003286.3
  
See co-cited genes in PubMed
Warning: Please see the Ensembl gene model ENSG00000198900 to get all the annotations available for this gene.


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006260 DNA replication IBA
 biological_processGO:0006265 DNA topological change IMP
 biological_processGO:0006338 chromatin remodeling IMP
 biological_processGO:0007059 chromosome segregation IBA
 biological_processGO:0007623 circadian rhythm IEP
 biological_processGO:0012501 programmed cell death NAS
 biological_processGO:0016032 viral process IEA
 biological_processGO:0016310 phosphorylation NAS
 biological_processGO:0018105 peptidyl-serine phosphorylation IMP
 biological_processGO:0032922 circadian regulation of gene expression IMP
 biological_processGO:0040016 embryonic cleavage IEA
 biological_processGO:0042493 response to drug IEP
 cellular_componentGO:0000228 nuclear chromosome IDA
 cellular_componentGO:0000932 P-body IDA
 cellular_componentGO:0001650 fibrillar center IDA
 cellular_componentGO:0005634 nucleus IDA
 cellular_componentGO:0005654 nucleoplasm TAS
 cellular_componentGO:0005730 nucleolus IMP
 cellular_componentGO:0009330 DNA topoisomerase complex (ATP-hydrolyzing) IMP
 cellular_componentGO:0031298 replication fork protection complex IBA
 cellular_componentGO:0032993 protein-DNA complex IMP
 cellular_componentGO:0043204 perikaryon IEA
 molecular_functionGO:0000978 RNA polymerase II proximal promoter sequence-specific DNA binding IDA
 molecular_functionGO:0003677 DNA binding IMP
 molecular_functionGO:0003682 chromatin binding IDA
 molecular_functionGO:0003690 double-stranded DNA binding IMP
 molecular_functionGO:0003697 single-stranded DNA binding IMP
 molecular_functionGO:0003723 RNA binding HDA
 molecular_functionGO:0003917 DNA topoisomerase type I activity IMP
 molecular_functionGO:0004674 protein serine/threonine kinase activity IMP
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0005524 ATP binding IMP
 molecular_functionGO:0019904 protein domain specific binding IPI
 molecular_functionGO:0097100 supercoiled DNA binding IMP


Pathways (from Reactome)
Pathway description
No match


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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