7153


Homo sapiens (NCBI)

Features
Gene ID: 7153
  
Biological name :
  
Synonyms : DNA topoisomerase II alpha / TOP2A / TOP2|TP2A
  
Possible biological names infered from orthology :
  
Species: Homo sapiens (NCBI)
  
Chr. number:
Strand:
Band:
Gene start:
Gene end:
  
Corresponding Affymetrix probe sets: 201291_s_at (Human Genome U133 Plus 2.0 Array)   201292_at (Human Genome U133 Plus 2.0 Array)   237469_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: RefSeq - 19913406
RefSeq - 530412779
RefSeq - 767995710
RefSeq - NC_000017.11
RefSeq - NG_027678.1
RefSeq - NP_001058.2
RefSeq - XP_005257689.1
RefSeq - XP_011523467.1
RefSeq - NM_001067.3
RefSeq - XM_011525165.2
RefSeq - XM_005257632.1
  
See co-cited genes in PubMed
Warning: Please see the Ensembl gene model ENSG00000131747 to get all the annotations available for this gene.


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000712 resolution of meiotic recombination intermediates IBA
 biological_processGO:0000819 sister chromatid segregation IBA
 biological_processGO:0002244 hematopoietic progenitor cell differentiation IEA
 biological_processGO:0006265 DNA topological change IMP
 biological_processGO:0006266 DNA ligation IDA
 biological_processGO:0006974 cellular response to DNA damage stimulus IDA
 biological_processGO:0007059 chromosome segregation IMP
 biological_processGO:0030263 apoptotic chromosome condensation IDA
 biological_processGO:0040016 embryonic cleavage IEA
 biological_processGO:0042752 regulation of circadian rhythm ISS
 biological_processGO:0043065 positive regulation of apoptotic process IDA
 biological_processGO:0044774 mitotic DNA integrity checkpoint IBA
 biological_processGO:0045070 positive regulation of viral genome replication IMP
 biological_processGO:0045870 positive regulation of single stranded viral RNA replication via double stranded DNA intermediate IMP
 biological_processGO:0045944 positive regulation of transcription by RNA polymerase II IEA
 biological_processGO:0048511 rhythmic process IEA
 biological_processGO:1905463 negative regulation of DNA duplex unwinding IMP
 cellular_componentGO:0000228 nuclear chromosome IDA
 cellular_componentGO:0000793 condensed chromosome IEA
 cellular_componentGO:0005634 nucleus IDA
 cellular_componentGO:0005654 nucleoplasm TAS
 cellular_componentGO:0005730 nucleolus IDA
 cellular_componentGO:0005814 centriole IDA
 cellular_componentGO:0009330 DNA topoisomerase complex (ATP-hydrolyzing) IDA
 cellular_componentGO:0019035 viral integration complex NAS
 cellular_componentGO:0032991 protein-containing complex IDA
 cellular_componentGO:1990904 ribonucleoprotein complex IDA
 molecular_functionGO:0000287 magnesium ion binding IDA
 molecular_functionGO:0003677 DNA binding IDA
 molecular_functionGO:0003682 chromatin binding IDA
 molecular_functionGO:0003723 RNA binding HDA
 molecular_functionGO:0003918 DNA topoisomerase type II (ATP-hydrolyzing) activity IMP
 molecular_functionGO:0005080 protein kinase C binding IPI
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0008022 protein C-terminus binding IPI
 molecular_functionGO:0008094 DNA-dependent ATPase activity IDA
 molecular_functionGO:0008144 drug binding IDA
 molecular_functionGO:0008301 DNA binding, bending IDA
 molecular_functionGO:0019899 enzyme binding IPI
 molecular_functionGO:0042803 protein homodimerization activity IPI
 molecular_functionGO:0042826 histone deacetylase binding IPI
 molecular_functionGO:0043130 ubiquitin binding IMP
 molecular_functionGO:0046982 protein heterodimerization activity IPI


Pathways (from Reactome)
Pathway description
No match


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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