7292


Homo sapiens (NCBI)
regulationcellresponseproductiontinterleukin-differentiationinflammatoryimmunereceptorbindingcytokineproliferationsignalingactivitytumornecrosisactivationt-helperalpha-betafactorimmunoglobulininterferon-gammamemorycd-positivetranscriptioncellularplasmamembrane

Features
Gene ID: 7292
  
Biological name :
  
Synonyms : CD134L|CD252|GP34|OX-40L|OX4OL|TNLG2B|TXGP1 / TNFSF4 / TNF superfamily member 4
  
Possible biological names infered from orthology :
  
Species: Homo sapiens (NCBI)
  
Chr. number:
Strand:
Band:
Gene start:
Gene end:
  
Corresponding Affymetrix probe sets: 207426_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: RefSeq - 662033902
RefSeq - NC_000001.11
RefSeq - XP_011508266.2
RefSeq - XP_016857717.1
RefSeq - XP_016857718.1
RefSeq - XP_016857719.1
RefSeq - NG_011477.1
RefSeq - 1034561544
RefSeq - 1034561546
RefSeq - NP_001284491.1
RefSeq - 1034561542
RefSeq - NP_003317.1
RefSeq - 1034561548
RefSeq - 4507603
RefSeq - XR_002957545.1
RefSeq - NM_001297562.1
RefSeq - NM_003326.4
RefSeq - XM_011509964.2
RefSeq - XM_017002228.1
RefSeq - XM_017002229.1
RefSeq - XM_017002230.1
RefSeq - XR_001737393.2
RefSeq - XR_001737394.2
RefSeq - XR_001737395.2
RefSeq - XR_002957543.1
  
See co-cited genes in PubMed
Warning: Please see the Ensembl gene model ENSG00000117586 to get all the annotations available for this gene.


Gene Ontology (GO)
cytokine productionresponse to stressimmune responseproduction of molecular mediator of immune responseimmune effector processcell communicationcellular response to stimulusresponse to external stimulusresponse to biotic stimulusregulation of molecular functionresponse to chemicalcell activationcell adhesionleukocyte proliferationanatomical structure developmentcellular developmental processnitrogen compound metabolic processbiosynthetic processcellular metabolic processprimary metabolic processorganic substance metabolic processmacromolecule localizationestablishment of localizationresponse to endogenous stimuluscytokine productionresponse to stressimmune responseproduction of molecular mediator of immune responseimmune effector processcell communicationcellular response to stimulusresponse to external stimulusresponse to biotic stimulusregulation of molecular functionresponse to chemicalcell activationcell adhesionleukocyte proliferationanatomical structure developmentcellular developmental processnitrogen compound metabolic processbiosynthetic processcellular metabolic processprimary metabolic processorganic substance metabolic processmacromolecule localizationestablishment of localizationresponse to endogenous stimuluscytokine productionresponse to stressimmune responseproduction of molecular mediator of immune responseimmune effector processcell communicationcellular response to stimulusresponse to external stimulusresponse to biotic stimulusregulation of molecular functionresponse to chemicalcell activationcell adhesionleukocyte proliferationanatomical structure developmentcellular developmental processnitrogen compound metabolic processbiosynthetic processcellular metabolic processprimary metabolic processorganic substance metabolic processmacromolecule localizationestablishment of localizationresponse to endogenous stimuluscytokine productionresponse to stressimmune responseproduction of molecular mediator of immune responseimmune effector processcell communicationcellular response to stimulusresponse to external stimulusresponse to biotic stimulusregulation of molecular functionresponse to chemicalcell activationcell adhesionleukocyte proliferationanatomical structure developmentcellular developmental processnitrogen compound metabolic processbiosynthetic processcellular metabolic processprimary metabolic processorganic substance metabolic processmacromolecule localizationestablishment of localizationresponse to endogenous stimuluscytokine productionresponse to stressimmune responseproduction of molecular mediator of immune responseimmune effector processcell communicationcellular response to stimulusresponse to external stimulusresponse to biotic stimulusregulation of molecular functionresponse to chemicalcell activationcell adhesionleukocyte proliferationanatomical structure developmentcellular developmental processnitrogen compound metabolic processbiosynthetic processcellular metabolic processprimary metabolic processorganic substance metabolic processmacromolecule localizationestablishment of localizationresponse to endogenous stimuluscytokine productionresponse to stressimmune responseproduction of molecular mediator of immune responseimmune effector processcell communicationcellular response to stimulusresponse to external stimulusresponse to biotic stimulusregulation of molecular functionresponse to chemicalcell activationcell adhesionleukocyte proliferationanatomical structure developmentcellular developmental processnitrogen compound metabolic processbiosynthetic processcellular metabolic processprimary metabolic processorganic substance metabolic processmacromolecule localizationestablishment of localizationresponse to endogenous stimuluscytokine productionresponse to stressimmune responseproduction of molecular mediator of immune responseimmune effector processcell communicationcellular response to stimulusresponse to external stimulusresponse to biotic stimulusregulation of molecular functionresponse to chemicalcell activationcell adhesionleukocyte proliferationanatomical structure developmentcellular developmental processnitrogen compound metabolic processbiosynthetic processcellular metabolic processprimary metabolic processorganic substance metabolic processmacromolecule localizationestablishment of localizationresponse to endogenous stimuluscytokine productionresponse to stressimmune responseproduction of molecular mediator of immune responseimmune effector processcell communicationcellular response to stimulusresponse to external stimulusresponse to biotic stimulusregulation of molecular functionresponse to chemicalcell activationcell adhesionleukocyte proliferationanatomical structure developmentcellular developmental processnitrogen compound metabolic processbiosynthetic processcellular metabolic processprimary metabolic processorganic substance metabolic processmacromolecule localizationestablishment of localizationresponse to endogenous stimuluscytokine productionresponse to stressimmune responseproduction of molecular mediator of immune responseimmune effector processcell communicationcellular response to stimulusresponse to external stimulusresponse to biotic stimulusregulation of molecular functionresponse to chemicalcell activationcell adhesionleukocyte proliferationanatomical structure developmentcellular developmental processnitrogen compound metabolic processbiosynthetic processcellular metabolic processprimary metabolic processorganic substance metabolic processmacromolecule localizationestablishment of localizationresponse to endogenous stimuluscytokine productionresponse to stressimmune responseproduction of molecular mediator of immune responseimmune effector processcell communicationcellular response to stimulusresponse to external stimulusresponse to biotic stimulusregulation of molecular functionresponse to chemicalcell activationcell adhesionleukocyte proliferationanatomical structure developmentcellular developmental processnitrogen compound metabolic processbiosynthetic processcellular metabolic processprimary metabolic processorganic substance metabolic processmacromolecule localizationestablishment of localizationresponse to endogenous stimuluscytokcytokine productionresporesponse to stressimmunimmune responseproduproduction of molecular mediator of immune responseimmunimmune effector processcell cell communicationcellucellular response to stimulusresporesponse to external stimulusresporesponse to biotic stimulusregulregulation of molecular functionresporesponse to chemicalcell cell activationcell cell adhesionleukoleukocyte proliferationanatoanatomical structure developmentcellucellular developmental processnitronitrogen compound metabolic processbiosybiosynthetic processcellucellular metabolic processprimaprimary metabolic processorganorganic substance metabolic processmacromacromolecule localizationestabestablishment of localizationresporesponse to endogenous stimulus
protein bindingreceptor regulator activityprotein bindingreceptor regulator activityprotein bindingreceptor regulator activityprotein bindingreceptor regulator activityprotein bindingreceptor regulator activityprotein bindingreceptor regulator activityprotein bindingreceptor regulator activityprotein bindingreceptor regulator activityprotein bindingreceptor regulator activityprotein bindingreceptor regulator activityprotein bindingprotein bindingreceptor regulator activityreceptor regulator activity
extracellular regioncellmembraneextracellular regioncellmembraneextracellular regioncellmembraneextracellular regioncellmembraneextracellular regioncellmembraneextracellular regioncellmembraneextracellular regioncellmembraneextracellular regioncellmembraneextracellular regioncellmembraneextracellular regioncellmembraneextracellular regionextracellular regioncellcellmembranemembrane
TypeGO IDTermEv.Code
 biological_processGO:0001819 positive regulation of cytokine production IBA
 biological_processGO:0002215 defense response to nematode ISS
 biological_processGO:0002526 acute inflammatory response ISS
 biological_processGO:0002726 positive regulation of T cell cytokine production ISS
 biological_processGO:0002819 regulation of adaptive immune response ISS
 biological_processGO:0002830 positive regulation of type 2 immune response ISS
 biological_processGO:0002891 positive regulation of immunoglobulin mediated immune response ISS
 biological_processGO:0006954 inflammatory response IBA
 biological_processGO:0006955 immune response IEA
 biological_processGO:0007165 signal transduction TAS
 biological_processGO:0008284 positive regulation of cell proliferation TAS
 biological_processGO:0009615 response to virus ISS
 biological_processGO:0010469 regulation of signaling receptor activity IEA
 biological_processGO:0032689 negative regulation of interferon-gamma production ISS
 biological_processGO:0032700 negative regulation of interleukin-17 production IDA
 biological_processGO:0032729 positive regulation of interferon-gamma production IDA
 biological_processGO:0032733 positive regulation of interleukin-10 production ISS
 biological_processGO:0032735 positive regulation of interleukin-12 production ISS
 biological_processGO:0032736 positive regulation of interleukin-13 production ISS
 biological_processGO:0032753 positive regulation of interleukin-4 production IDA
 biological_processGO:0032755 positive regulation of interleukin-6 production IDA
 biological_processGO:0033209 tumor necrosis factor-mediated signaling pathway TAS
 biological_processGO:0035709 memory T cell activation ISS
 biological_processGO:0035712 T-helper 2 cell activation ISS
 biological_processGO:0035713 response to nitrogen dioxide ISS
 biological_processGO:0042102 positive regulation of T cell proliferation IBA
 biological_processGO:0043372 positive regulation of CD4-positive, alpha-beta T cell differentiation ISS
 biological_processGO:0043382 positive regulation of memory T cell differentiation ISS
 biological_processGO:0043433 negative regulation of DNA-binding transcription factor activity ISS
 biological_processGO:0045590 negative regulation of regulatory T cell differentiation ISS
 biological_processGO:0045626 negative regulation of T-helper 1 cell differentiation ISS
 biological_processGO:0045630 positive regulation of T-helper 2 cell differentiation ISS
 biological_processGO:0045892 negative regulation of transcription, DNA-templated ISS
 biological_processGO:0046641 positive regulation of alpha-beta T cell proliferation ISS
 biological_processGO:0050727 regulation of inflammatory response ISS
 biological_processGO:0050729 positive regulation of inflammatory response IDA
 biological_processGO:0050871 positive regulation of B cell activation ISS
 biological_processGO:0051024 positive regulation of immunoglobulin secretion ISS
 biological_processGO:0071222 cellular response to lipopolysaccharide IDA
 biological_processGO:0071380 cellular response to prostaglandin E stimulus IDA
 biological_processGO:0071954 chemokine (C-C motif) ligand 11 production ISS
 biological_processGO:1900281 positive regulation of CD4-positive, alpha-beta T cell costimulation ISS
 biological_processGO:2000572 positive regulation of interleukin-4-dependent isotype switching to IgE isotypes ISS
 cellular_componentGO:0005615 extracellular space IDA
 cellular_componentGO:0005886 plasma membrane TAS
 cellular_componentGO:0005887 integral component of plasma membrane NAS
 cellular_componentGO:0009986 cell surface IDA
 molecular_functionGO:0005102 signaling receptor binding TAS
 molecular_functionGO:0005125 cytokine activity IEA
 molecular_functionGO:0005164 tumor necrosis factor receptor binding IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0032813 tumor necrosis factor receptor superfamily binding ISS


Pathways (from Reactome)
Pathway description
No match


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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