729230


Homo sapiens (NCBI)

Features
Gene ID: 729230
  
Biological name :
  
Synonyms : CC-CKR-2|CCR-2|CCR2A|CCR2B|CD192|CKR2|CKR2A|CKR2B|CMKBR2|MCP-1-R / C-C motif chemokine receptor 2 / CCR2
  
Possible biological names infered from orthology :
  
Species: Homo sapiens (NCBI)
  
Chr. number:
Strand:
Band:
Gene start:
Gene end:
  
Corresponding Affymetrix probe sets: 206978_at (Human Genome U133 Plus 2.0 Array)   207794_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: RefSeq - 183979980
RefSeq - 183979982
RefSeq - 767924176
RefSeq - NC_000003.12
RefSeq - NG_021428.1
RefSeq - NP_001116513.2
RefSeq - NP_001116868.1
RefSeq - XP_011532371.1
RefSeq - NM_001123041.2
RefSeq - NM_001123396.2
RefSeq - XM_011534069.1
  
See co-cited genes in PubMed
Warning: Please see the Ensembl gene model ENSG00000121807 to get all the annotations available for this gene.


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001974 blood vessel remodeling ISS
 biological_processGO:0002407 dendritic cell chemotaxis TAS
 biological_processGO:0002548 monocyte chemotaxis IEA
 biological_processGO:0002827 positive regulation of T-helper 1 type immune response ISS
 biological_processGO:0002829 negative regulation of type 2 immune response ISS
 biological_processGO:0006874 cellular calcium ion homeostasis ISS
 biological_processGO:0006935 chemotaxis TAS
 biological_processGO:0006954 inflammatory response IEA
 biological_processGO:0006955 immune response TAS
 biological_processGO:0006959 humoral immune response IEA
 biological_processGO:0006968 cellular defense response IEA
 biological_processGO:0007186 G-protein coupled receptor signaling pathway TAS
 biological_processGO:0007194 negative regulation of adenylate cyclase activity TAS
 biological_processGO:0007204 positive regulation of cytosolic calcium ion concentration TAS
 biological_processGO:0007259 JAK-STAT cascade TAS
 biological_processGO:0009611 response to wounding TAS
 biological_processGO:0010574 regulation of vascular endothelial growth factor production ISS
 biological_processGO:0010820 positive regulation of T cell chemotaxis ISS
 biological_processGO:0016032 viral process IEA
 biological_processGO:0016525 negative regulation of angiogenesis ISS
 biological_processGO:0019221 cytokine-mediated signaling pathway TAS
 biological_processGO:0019233 sensory perception of pain IEA
 biological_processGO:0019722 calcium-mediated signaling IBA
 biological_processGO:0019725 cellular homeostasis ISS
 biological_processGO:0030097 hemopoiesis IEA
 biological_processGO:0032729 positive regulation of interferon-gamma production ISS
 biological_processGO:0032743 positive regulation of interleukin-2 production ISS
 biological_processGO:0035705 T-helper 17 cell chemotaxis ISS
 biological_processGO:0042535 positive regulation of tumor necrosis factor biosynthetic process ISS
 biological_processGO:0043310 negative regulation of eosinophil degranulation ISS
 biological_processGO:0046641 positive regulation of alpha-beta T cell proliferation ISS
 biological_processGO:0048873 homeostasis of number of cells within a tissue IEA
 biological_processGO:0050729 positive regulation of inflammatory response ISS
 biological_processGO:0050870 positive regulation of T cell activation ISS
 biological_processGO:0060326 cell chemotaxis IBA
 biological_processGO:0061756 leukocyte adhesion to vascular endothelial cell IEA
 biological_processGO:0070098 chemokine-mediated signaling pathway ISS
 biological_processGO:0090026 positive regulation of monocyte chemotaxis ISS
 biological_processGO:0090265 positive regulation of immune complex clearance by monocytes and macrophages ISS
 biological_processGO:0097350 neutrophil clearance IEA
 biological_processGO:1903238 positive regulation of leukocyte tethering or rolling IEA
 biological_processGO:2000439 positive regulation of monocyte extravasation ISS
 biological_processGO:2000451 positive regulation of CD8-positive, alpha-beta T cell extravasation ISS
 biological_processGO:2000464 positive regulation of astrocyte chemotaxis IDA
 biological_processGO:2000473 positive regulation of hematopoietic stem cell migration ISS
 cellular_componentGO:0005737 cytoplasm IDA
 cellular_componentGO:0005829 cytosol ISS
 cellular_componentGO:0005886 plasma membrane TAS
 cellular_componentGO:0005887 integral component of plasma membrane TAS
 cellular_componentGO:0009897 external side of plasma membrane IEA
 cellular_componentGO:0016021 integral component of membrane TAS
 cellular_componentGO:0030425 dendrite ISS
 cellular_componentGO:0043025 neuronal cell body ISS
 cellular_componentGO:0043204 perikaryon ISS
 cellular_componentGO:0048471 perinuclear region of cytoplasm ISS
 molecular_functionGO:0004950 chemokine receptor activity TAS
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0016493 C-C chemokine receptor activity IEA
 molecular_functionGO:0019956 chemokine binding IBA
 molecular_functionGO:0019957 C-C chemokine binding IBA
 molecular_functionGO:0031727 CCR2 chemokine receptor binding IDA
 molecular_functionGO:0035715 chemokine (C-C motif) ligand 2 binding IEA
 molecular_functionGO:0035716 chemokine (C-C motif) ligand 12 binding IEA
 molecular_functionGO:0035717 chemokine (C-C motif) ligand 7 binding IEA
 molecular_functionGO:0042803 protein homodimerization activity ISS


Pathways (from Reactome)
Pathway description
No match


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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