7422


Homo sapiens (NCBI)

Features
Gene ID: 7422
  
Biological name :
  
Synonyms : MVCD1|VEGF|VPF / vascular endothelial growth factor A / VEGFA
  
Possible biological names infered from orthology :
  
Species: Homo sapiens (NCBI)
  
Chr. number:
Strand:
Band:
Gene start:
Gene end:
  
Corresponding Affymetrix probe sets: 210512_s_at (Human Genome U133 Plus 2.0 Array)   210513_s_at (Human Genome U133 Plus 2.0 Array)   211527_x_at (Human Genome U133 Plus 2.0 Array)   212171_x_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: RefSeq - 76781482
RefSeq - 284172459
RefSeq - 284172461
RefSeq - 284172463
RefSeq - 284172465
RefSeq - 284172467
RefSeq - 284172469
RefSeq - 284172471
RefSeq - 284172473
RefSeq - 324120930
RefSeq - 324120932
RefSeq - 559098480
RefSeq - 76781480
RefSeq - 76781481
RefSeq - 284172457
RefSeq - 76781483
RefSeq - 76781484
RefSeq - 76781485
RefSeq - 76781487
RefSeq - 949394728
RefSeq - NC_000006.12
RefSeq - NG_008732.1
RefSeq - NP_001020537.2
RefSeq - NP_001020538.2
RefSeq - NP_001020539.2
RefSeq - NP_001020540.2
RefSeq - NP_001020541.2
RefSeq - NP_001028928.1
RefSeq - NP_001165093.1
RefSeq - NP_001165094.1
RefSeq - NP_001165095.1
RefSeq - NP_001165096.1
RefSeq - NP_001165097.1
RefSeq - NP_001165098.1
RefSeq - NP_001165099.1
RefSeq - NP_001165100.1
RefSeq - NP_001165101.1
RefSeq - NP_001191313.1
RefSeq - NP_001191314.1
RefSeq - NP_001273973.1
RefSeq - NP_001303939.1
RefSeq - NP_003367.4
RefSeq - NM_001025366.2
RefSeq - NM_001025367.2
RefSeq - NM_001025368.2
RefSeq - NM_001025369.2
RefSeq - NM_001025370.2
RefSeq - NM_001033756.2
RefSeq - NM_001171622.1
RefSeq - NM_001171623.1
RefSeq - NM_001171624.1
RefSeq - NM_001171625.1
RefSeq - NM_001171626.1
RefSeq - NM_001171627.1
RefSeq - NM_001171628.1
RefSeq - NM_001171629.1
RefSeq - NM_001171630.1
RefSeq - NM_001204384.1
RefSeq - NM_001204385.1
RefSeq - NM_001287044.1
RefSeq - NM_001317010.1
RefSeq - NM_003376.5
  
See co-cited genes in PubMed
Warning: Please see the Ensembl gene model ENSG00000112715 to get all the annotations available for this gene.


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000122 negative regulation of transcription by RNA polymerase II IDA
 biological_processGO:0001525 angiogenesis IDA
 biological_processGO:0001541 ovarian follicle development ISS
 biological_processGO:0001569 branching involved in blood vessel morphogenesis ISS
 biological_processGO:0001570 vasculogenesis TAS
 biological_processGO:0001666 response to hypoxia IDA
 biological_processGO:0001701 in utero embryonic development ISS
 biological_processGO:0001822 kidney development ISS
 biological_processGO:0001934 positive regulation of protein phosphorylation IDA
 biological_processGO:0001938 positive regulation of endothelial cell proliferation ISS
 biological_processGO:0002040 sprouting angiogenesis IBA
 biological_processGO:0002042 cell migration involved in sprouting angiogenesis IDA
 biological_processGO:0002052 positive regulation of neuroblast proliferation ISS
 biological_processGO:0002053 positive regulation of mesenchymal cell proliferation ISS
 biological_processGO:0002092 positive regulation of receptor internalization IDA
 biological_processGO:0002576 platelet degranulation TAS
 biological_processGO:0002687 positive regulation of leukocyte migration TAS
 biological_processGO:0003007 heart morphogenesis ISS
 biological_processGO:0003151 outflow tract morphogenesis ISS
 biological_processGO:0003169 coronary vein morphogenesis ISS
 biological_processGO:0006357 regulation of transcription by RNA polymerase II TAS
 biological_processGO:0007399 nervous system development TAS
 biological_processGO:0007498 mesoderm development ISS
 biological_processGO:0007595 lactation ISS
 biological_processGO:0008284 positive regulation of cell proliferation IMP
 biological_processGO:0008360 regulation of cell shape IDA
 biological_processGO:0010469 regulation of signaling receptor activity IEA
 biological_processGO:0010595 positive regulation of endothelial cell migration IDA
 biological_processGO:0010628 positive regulation of gene expression IDA
 biological_processGO:0010629 negative regulation of gene expression IDA
 biological_processGO:0019221 cytokine-mediated signaling pathway TAS
 biological_processGO:0030224 monocyte differentiation IDA
 biological_processGO:0030225 macrophage differentiation IDA
 biological_processGO:0030324 lung development ISS
 biological_processGO:0030335 positive regulation of cell migration IDA
 biological_processGO:0030855 epithelial cell differentiation ISS
 biological_processGO:0030949 positive regulation of vascular endothelial growth factor receptor signaling pathway IDA
 biological_processGO:0031077 post-embryonic camera-type eye development ISS
 biological_processGO:0031334 positive regulation of protein complex assembly IDA
 biological_processGO:0031954 positive regulation of protein autophosphorylation IDA
 biological_processGO:0032147 activation of protein kinase activity IDA
 biological_processGO:0032793 positive regulation of CREB transcription factor activity IDA
 biological_processGO:0033138 positive regulation of peptidyl-serine phosphorylation IDA
 biological_processGO:0035148 tube formation IDA
 biological_processGO:0035767 endothelial cell chemotaxis IDA
 biological_processGO:0035924 cellular response to vascular endothelial growth factor stimulus IDA
 biological_processGO:0036303 lymph vessel morphogenesis ISS
 biological_processGO:0038033 positive regulation of endothelial cell chemotaxis by VEGF-activated vascular endothelial growth factor receptor signaling pathway IDA
 biological_processGO:0038084 vascular endothelial growth factor signaling pathway IBA
 biological_processGO:0038091 positive regulation of cell proliferation by VEGF-activated platelet derived growth factor receptor signaling pathway IDA
 biological_processGO:0038190 VEGF-activated neuropilin signaling pathway ISS
 biological_processGO:0042462 eye photoreceptor cell development ISS
 biological_processGO:0042531 positive regulation of tyrosine phosphorylation of STAT protein IDA
 biological_processGO:0043066 negative regulation of apoptotic process IMP
 biological_processGO:0043129 surfactant homeostasis ISS
 biological_processGO:0043154 negative regulation of cysteine-type endopeptidase activity involved in apoptotic process IDA
 biological_processGO:0043406 positive regulation of MAP kinase activity IDA
 biological_processGO:0043536 positive regulation of blood vessel endothelial cell migration IDA
 biological_processGO:0045766 positive regulation of angiogenesis IMP
 biological_processGO:0045785 positive regulation of cell adhesion IDA
 biological_processGO:0045944 positive regulation of transcription by RNA polymerase II IMP
 biological_processGO:0048010 vascular endothelial growth factor receptor signaling pathway TAS
 biological_processGO:0048469 cell maturation ISS
 biological_processGO:0048593 camera-type eye morphogenesis ISS
 biological_processGO:0048739 cardiac muscle fiber development ISS
 biological_processGO:0048754 branching morphogenesis of an epithelial tube ISS
 biological_processGO:0048842 positive regulation of axon extension involved in axon guidance ISS
 biological_processGO:0048844 artery morphogenesis ISS
 biological_processGO:0050679 positive regulation of epithelial cell proliferation ISS
 biological_processGO:0050731 positive regulation of peptidyl-tyrosine phosphorylation IDA
 biological_processGO:0050918 positive chemotaxis IDA
 biological_processGO:0050927 positive regulation of positive chemotaxis IDA
 biological_processGO:0050930 induction of positive chemotaxis NAS
 biological_processGO:0051272 positive regulation of cellular component movement IDA
 biological_processGO:0051781 positive regulation of cell division IEA
 biological_processGO:0051894 positive regulation of focal adhesion assembly IDA
 biological_processGO:0060319 primitive erythrocyte differentiation ISS
 biological_processGO:0060749 mammary gland alveolus development ISS
 biological_processGO:0060754 positive regulation of mast cell chemotaxis IBA
 biological_processGO:0060948 cardiac vascular smooth muscle cell development ISS
 biological_processGO:0060982 coronary artery morphogenesis ISS
 biological_processGO:0061418 regulation of transcription from RNA polymerase II promoter in response to hypoxia TAS
 biological_processGO:0061419 positive regulation of transcription from RNA polymerase II promoter in response to hypoxia IMP
 biological_processGO:0071456 cellular response to hypoxia IDA
 biological_processGO:0071542 dopaminergic neuron differentiation ISS
 biological_processGO:0071679 commissural neuron axon guidance ISS
 biological_processGO:0090037 positive regulation of protein kinase C signaling IDA
 biological_processGO:0090050 positive regulation of cell migration involved in sprouting angiogenesis IMP
 biological_processGO:0090190 positive regulation of branching involved in ureteric bud morphogenesis ISS
 biological_processGO:0090259 regulation of retinal ganglion cell axon guidance ISS
 biological_processGO:0097475 motor neuron migration ISS
 biological_processGO:0097533 cellular stress response to acid chemical IDA
 biological_processGO:1900086 positive regulation of peptidyl-tyrosine autophosphorylation IDA
 biological_processGO:1900745 positive regulation of p38MAPK cascade IDA
 biological_processGO:1901727 positive regulation of histone deacetylase activity IDA
 biological_processGO:1902336 positive regulation of retinal ganglion cell axon guidance ISS
 biological_processGO:1903572 positive regulation of protein kinase D signaling IDA
 biological_processGO:1903589 positive regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis IGI
 biological_processGO:1903672 positive regulation of sprouting angiogenesis IGI
 cellular_componentGO:0005576 extracellular region TAS
 cellular_componentGO:0005615 extracellular space ISS
 cellular_componentGO:0005737 cytoplasm IDA
 cellular_componentGO:0009986 cell surface IDA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0030141 secretory granule IDA
 cellular_componentGO:0031012 extracellular matrix NAS
 cellular_componentGO:0031093 platelet alpha granule lumen TAS
 molecular_functionGO:0001968 fibronectin binding IDA
 molecular_functionGO:0005125 cytokine activity ISS
 molecular_functionGO:0005161 platelet-derived growth factor receptor binding IPI
 molecular_functionGO:0005172 vascular endothelial growth factor receptor binding IPI
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0008083 growth factor activity ISS
 molecular_functionGO:0008201 heparin binding IMP
 molecular_functionGO:0042056 chemoattractant activity IDA
 molecular_functionGO:0042802 identical protein binding IPI
 molecular_functionGO:0042803 protein homodimerization activity ISS
 molecular_functionGO:0043183 vascular endothelial growth factor receptor 1 binding IPI
 molecular_functionGO:0043184 vascular endothelial growth factor receptor 2 binding IPI
 molecular_functionGO:0043185 vascular endothelial growth factor receptor 3 binding IBA
 molecular_functionGO:0046982 protein heterodimerization activity IDA
 molecular_functionGO:0048018 receptor ligand activity IPI
 molecular_functionGO:0050840 extracellular matrix binding IC


Pathways (from Reactome)
Pathway description
No match


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

0 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2024
contact: otassy@igbmc.fr