7466


Homo sapiens (NCBI)
proteinregulationendoplasmicreticulumbindingprocesshomeostasisresponsetranscriptioncalciumionapoptoticdevelopmentperceptionpathway-mediatedunfoldedcellfactormetabolicmembranernapolymeraseiikidneyrenalwatereroverloadvisual

Features
Gene ID: 7466
  
Biological name :
  
Synonyms : CTRCT41|WFRS|WFS|WFSL / WFS1 / wolframin ER transmembrane glycoprotein
  
Possible biological names infered from orthology :
  
Species: Homo sapiens (NCBI)
  
Chr. number:
Strand:
Band:
Gene start:
Gene end:
  
Corresponding Affymetrix probe sets: 1555270_a_at (Human Genome U133 Plus 2.0 Array)   202908_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: RefSeq - 1034641076
RefSeq - 224994203
RefSeq - 224994205
RefSeq - NC_000004.12
RefSeq - NG_011700.1
RefSeq - NP_001139325.1
RefSeq - NP_005996.2
RefSeq - XP_016864075.1
RefSeq - NM_001145853.1
RefSeq - NM_006005.3
RefSeq - XM_017008586.1
  
See co-cited genes in PubMed
Warning: Please see the Ensembl gene model ENSG00000109501 to get all the annotations available for this gene.


Gene Ontology (GO)
nitrogen compound metabolic processbiosynthetic processcellular metabolic processprimary metabolic processorganic substance metabolic processanatomical structure developmentregulation of biological qualitysystem processresponse to stresscell communicationresponse to biotic stimuluscellular response to stimulusprotein foldingcatabolic processresponse to chemicalcell deathregulation of molecular functionestablishment of localizationnitrogen compound metabolic processbiosynthetic processcellular metabolic processprimary metabolic processorganic substance metabolic processanatomical structure developmentregulation of biological qualitysystem processresponse to stresscell communicationresponse to biotic stimuluscellular response to stimulusprotein foldingcatabolic processresponse to chemicalcell deathregulation of molecular functionestablishment of localizationnitrogen compound metabolic processbiosynthetic processcellular metabolic processprimary metabolic processorganic substance metabolic processanatomical structure developmentregulation of biological qualitysystem processresponse to stresscell communicationresponse to biotic stimuluscellular response to stimulusprotein foldingcatabolic processresponse to chemicalcell deathregulation of molecular functionestablishment of localizationnitrogen compound metabolic processbiosynthetic processcellular metabolic processprimary metabolic processorganic substance metabolic processanatomical structure developmentregulation of biological qualitysystem processresponse to stresscell communicationresponse to biotic stimuluscellular response to stimulusprotein foldingcatabolic processresponse to chemicalcell deathregulation of molecular functionestablishment of localizationnitrogen compound metabolic processbiosynthetic processcellular metabolic processprimary metabolic processorganic substance metabolic processanatomical structure developmentregulation of biological qualitysystem processresponse to stresscell communicationresponse to biotic stimuluscellular response to stimulusprotein foldingcatabolic processresponse to chemicalcell deathregulation of molecular functionestablishment of localizationnitrogen compound metabolic processbiosynthetic processcellular metabolic processprimary metabolic processorganic substance metabolic processanatomical structure developmentregulation of biological qualitysystem processresponse to stresscell communicationresponse to biotic stimuluscellular response to stimulusprotein foldingcatabolic processresponse to chemicalcell deathregulation of molecular functionestablishment of localizationnitrogen compound metabolic processbiosynthetic processcellular metabolic processprimary metabolic processorganic substance metabolic processanatomical structure developmentregulation of biological qualitysystem processresponse to stresscell communicationresponse to biotic stimuluscellular response to stimulusprotein foldingcatabolic processresponse to chemicalcell deathregulation of molecular functionestablishment of localizationnitrogen compound metabolic processbiosynthetic processcellular metabolic processprimary metabolic processorganic substance metabolic processanatomical structure developmentregulation of biological qualitysystem processresponse to stresscell communicationresponse to biotic stimuluscellular response to stimulusprotein foldingcatabolic processresponse to chemicalcell deathregulation of molecular functionestablishment of localizationnitrogen compound metabolic processbiosynthetic processcellular metabolic processprimary metabolic processorganic substance metabolic processanatomical structure developmentregulation of biological qualitysystem processresponse to stresscell communicationresponse to biotic stimuluscellular response to stimulusprotein foldingcatabolic processresponse to chemicalcell deathregulation of molecular functionestablishment of localizationnitrogen compound metabolic processbiosynthetic processcellular metabolic processprimary metabolic processorganic substance metabolic processanatomical structure developmentregulation of biological qualitysystem processresponse to stresscell communicationresponse to biotic stimuluscellular response to stimulusprotein foldingcatabolic processresponse to chemicalcell deathregulation of molecular functionestablishment of localizationnitrogenitrogen compound metabolic processbiosyntbiosynthetic processcellulacellular metabolic processprimaryprimary metabolic processorganicorganic substance metabolic processanatomianatomical structure developmentregulatregulation of biological qualitysystem system processresponsresponse to stresscell cocell communicationresponsresponse to biotic stimuluscellulacellular response to stimulusproteinprotein foldingcatabolcatabolic processresponsresponse to chemicalcell decell deathregulatregulation of molecular functionestabliestablishment of localization
protein bindingprotein bindingprotein bindingprotein bindingprotein bindingprotein bindingprotein bindingprotein bindingprotein bindingprotein bindingprotein bindingprotein binding
cellprotein-containing complexorganellemembrane-enclosed lumenmembranecellprotein-containing complexorganellemembrane-enclosed lumenmembranecellprotein-containing complexorganellemembrane-enclosed lumenmembranecellprotein-containing complexorganellemembrane-enclosed lumenmembranecellprotein-containing complexorganellemembrane-enclosed lumenmembranecellprotein-containing complexorganellemembrane-enclosed lumenmembranecellprotein-containing complexorganellemembrane-enclosed lumenmembranecellprotein-containing complexorganellemembrane-enclosed lumenmembranecellprotein-containing complexorganellemembrane-enclosed lumenmembranecellprotein-containing complexorganellemembrane-enclosed lumenmembranecellcellprotein-containing complexprotein-containing complexorganelleorganellemembrane-enclosed lumenmembrane-enclosed lumenmembranemembrane
TypeGO IDTermEv.Code
 biological_processGO:0000122 negative regulation of transcription by RNA polymerase II IDA
 biological_processGO:0001822 kidney development IMP
 biological_processGO:0003091 renal water homeostasis IMP
 biological_processGO:0006983 ER overload response TAS
 biological_processGO:0007601 visual perception IMP
 biological_processGO:0007605 sensory perception of sound IMP
 biological_processGO:0022417 protein maturation by protein folding IC
 biological_processGO:0030433 ubiquitin-dependent ERAD pathway ISS
 biological_processGO:0031016 pancreas development IEA
 biological_processGO:0031398 positive regulation of protein ubiquitination ISS
 biological_processGO:0032469 endoplasmic reticulum calcium ion homeostasis IDA
 biological_processGO:0034976 response to endoplasmic reticulum stress IDA
 biological_processGO:0036498 IRE1-mediated unfolded protein response TAS
 biological_processGO:0042048 olfactory behavior IEA
 biological_processGO:0042593 glucose homeostasis IMP
 biological_processGO:0043069 negative regulation of programmed cell death IMP
 biological_processGO:0043433 negative regulation of DNA-binding transcription factor activity IDA
 biological_processGO:0043524 negative regulation of neuron apoptotic process IMP
 biological_processGO:0043687 post-translational protein modification TAS
 biological_processGO:0044267 cellular protein metabolic process TAS
 biological_processGO:0045927 positive regulation of growth ISS
 biological_processGO:0050821 protein stabilization TAS
 biological_processGO:0050877 nervous system process IMP
 biological_processGO:0051247 positive regulation of protein metabolic process IDA
 biological_processGO:0051928 positive regulation of calcium ion transport IDA
 biological_processGO:0055074 calcium ion homeostasis IDA
 biological_processGO:1902236 negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway IEA
 biological_processGO:1903892 negative regulation of ATF6-mediated unfolded protein response IDA
 biological_processGO:2000675 negative regulation of type B pancreatic cell apoptotic process IMP
 cellular_componentGO:0000502 proteasome complex IEA
 cellular_componentGO:0005783 endoplasmic reticulum ISS
 cellular_componentGO:0005788 endoplasmic reticulum lumen TAS
 cellular_componentGO:0005789 endoplasmic reticulum membrane TAS
 cellular_componentGO:0030176 integral component of endoplasmic reticulum membrane IDA
 cellular_componentGO:0030425 dendrite ISS
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0005516 calmodulin binding IEA
 molecular_functionGO:0031625 ubiquitin protein ligase binding IDA
 molecular_functionGO:0033613 activating transcription factor binding IEA
 molecular_functionGO:0048306 calcium-dependent protein binding IEA
 molecular_functionGO:0051117 ATPase binding IPI


Pathways (from Reactome)
Pathway description
No match


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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