7473


Homo sapiens (NCBI)
signalingwntpathwayregulationcellcanonicalinvolvedmorphogenesisdifferentiationformationaxonstemextracellularbindingguidanceanterioraxisspecificationreceptoractivityneuronembryonicproliferationlumenmembraneproteinmesodermgametegenerationposterior

Features
Gene ID: 7473
  
Biological name :
  
Synonyms : INT4|TETAMS / WNT3 / Wnt family member 3
  
Possible biological names infered from orthology :
  
Species: Homo sapiens (NCBI)
  
Chr. number:
Strand:
Band:
Gene start:
Gene end:
  
Corresponding Affymetrix probe sets: 221455_s_at (Human Genome U133 Plus 2.0 Array)   229103_at (Human Genome U133 Plus 2.0 Array)   231743_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: RefSeq - NT_187663.1
RefSeq - NC_000017.11
RefSeq - NG_008084.2
RefSeq - 13540477
RefSeq - NP_110380.1
RefSeq - NT_167251.2
RefSeq - NM_030753.4
  
See co-cited genes in PubMed
Warning: Please see the Ensembl gene model ENSG00000108379 to get all the annotations available for this gene.


Gene Ontology (GO)
cellular component organizationanatomical structure developmentcellular developmental processmulticellular organism reproductionresponse to external stimulusresponse to chemicalmovement of cell or subcellular componentcell communicationregulation of molecular functioncellular response to stimulusorganic substance metabolic processossificationregulation of biological qualitycell growthdevelopmental growthdevelopmental inductionstem cell proliferationcellular component organizationanatomical structure developmentcellular developmental processmulticellular organism reproductionresponse to external stimulusresponse to chemicalmovement of cell or subcellular componentcell communicationregulation of molecular functioncellular response to stimulusorganic substance metabolic processossificationregulation of biological qualitycell growthdevelopmental growthdevelopmental inductionstem cell proliferationcellular component organizationanatomical structure developmentcellular developmental processmulticellular organism reproductionresponse to external stimulusresponse to chemicalmovement of cell or subcellular componentcell communicationregulation of molecular functioncellular response to stimulusorganic substance metabolic processossificationregulation of biological qualitycell growthdevelopmental growthdevelopmental inductionstem cell proliferationcellular component organizationanatomical structure developmentcellular developmental processmulticellular organism reproductionresponse to external stimulusresponse to chemicalmovement of cell or subcellular componentcell communicationregulation of molecular functioncellular response to stimulusorganic substance metabolic processossificationregulation of biological qualitycell growthdevelopmental growthdevelopmental inductionstem cell proliferationcellular component organizationanatomical structure developmentcellular developmental processmulticellular organism reproductionresponse to external stimulusresponse to chemicalmovement of cell or subcellular componentcell communicationregulation of molecular functioncellular response to stimulusorganic substance metabolic processossificationregulation of biological qualitycell growthdevelopmental growthdevelopmental inductionstem cell proliferationcellular component organizationanatomical structure developmentcellular developmental processmulticellular organism reproductionresponse to external stimulusresponse to chemicalmovement of cell or subcellular componentcell communicationregulation of molecular functioncellular response to stimulusorganic substance metabolic processossificationregulation of biological qualitycell growthdevelopmental growthdevelopmental inductionstem cell proliferationcellular component organizationanatomical structure developmentcellular developmental processmulticellular organism reproductionresponse to external stimulusresponse to chemicalmovement of cell or subcellular componentcell communicationregulation of molecular functioncellular response to stimulusorganic substance metabolic processossificationregulation of biological qualitycell growthdevelopmental growthdevelopmental inductionstem cell proliferationcellular component organizationanatomical structure developmentcellular developmental processmulticellular organism reproductionresponse to external stimulusresponse to chemicalmovement of cell or subcellular componentcell communicationregulation of molecular functioncellular response to stimulusorganic substance metabolic processossificationregulation of biological qualitycell growthdevelopmental growthdevelopmental inductionstem cell proliferationcellular component organizationanatomical structure developmentcellular developmental processmulticellular organism reproductionresponse to external stimulusresponse to chemicalmovement of cell or subcellular componentcell communicationregulation of molecular functioncellular response to stimulusorganic substance metabolic processossificationregulation of biological qualitycell growthdevelopmental growthdevelopmental inductionstem cell proliferationcellular component organizationanatomical structure developmentcellular developmental processmulticellular organism reproductionresponse to external stimulusresponse to chemicalmovement of cell or subcellular componentcell communicationregulation of molecular functioncellular response to stimulusorganic substance metabolic processossificationregulation of biological qualitycell growthdevelopmental growthdevelopmental inductionstem cell proliferationcellularcellular component organizationanatomicanatomical structure developmentcellularcellular developmental processmulticelmulticellular organism reproductionresponseresponse to external stimulusresponseresponse to chemicalmovementmovement of cell or subcellular componentcell comcell communicationregulatiregulation of molecular functioncellularcellular response to stimulusorganic organic substance metabolic processossificaossificationregulatiregulation of biological qualitycell grocell growthdevelopmdevelopmental growthdevelopmdevelopmental inductionstem celstem cell proliferation
protein bindingreceptor regulator activityprotein bindingreceptor regulator activityprotein bindingreceptor regulator activityprotein bindingreceptor regulator activityprotein bindingreceptor regulator activityprotein bindingreceptor regulator activityprotein bindingreceptor regulator activityprotein bindingreceptor regulator activityprotein bindingreceptor regulator activityprotein bindingreceptor regulator activityprotein bindingprotein bindingreceptor regulator activityreceptor regulator activity
extracellular regioncellorganellemembrane-enclosed lumenmembraneprotein-containing complexextracellular regioncellorganellemembrane-enclosed lumenmembraneprotein-containing complexextracellular regioncellorganellemembrane-enclosed lumenmembraneprotein-containing complexextracellular regioncellorganellemembrane-enclosed lumenmembraneprotein-containing complexextracellular regioncellorganellemembrane-enclosed lumenmembraneprotein-containing complexextracellular regioncellorganellemembrane-enclosed lumenmembraneprotein-containing complexextracellular regioncellorganellemembrane-enclosed lumenmembraneprotein-containing complexextracellular regioncellorganellemembrane-enclosed lumenmembraneprotein-containing complexextracellular regioncellorganellemembrane-enclosed lumenmembraneprotein-containing complexextracellular regioncellorganellemembrane-enclosed lumenmembraneprotein-containing complexextracellular regionextracellular regioncellcellorganelleorganellemembrane-enclosed lumenmembrane-enclosed lumenmembranemembraneprotein-containing compprotein-containing complex
TypeGO IDTermEv.Code
 biological_processGO:0000902 cell morphogenesis IMP
 biological_processGO:0001707 mesoderm formation IEA
 biological_processGO:0007276 gamete generation IEA
 biological_processGO:0007411 axon guidance IEA
 biological_processGO:0009948 anterior/posterior axis specification IEA
 biological_processGO:0009950 dorsal/ventral axis specification IEA
 biological_processGO:0010469 regulation of signaling receptor activity IEA
 biological_processGO:0010628 positive regulation of gene expression IDA
 biological_processGO:0016055 Wnt signaling pathway TAS
 biological_processGO:0030177 positive regulation of Wnt signaling pathway IEA
 biological_processGO:0030182 neuron differentiation ISS
 biological_processGO:0035115 embryonic forelimb morphogenesis IEA
 biological_processGO:0035116 embryonic hindlimb morphogenesis IEA
 biological_processGO:0044338 canonical Wnt signaling pathway involved in mesenchymal stem cell differentiation IMP
 biological_processGO:0044339 canonical Wnt signaling pathway involved in osteoblast differentiation IMP
 biological_processGO:0045165 cell fate commitment IBA
 biological_processGO:0048697 positive regulation of collateral sprouting in absence of injury IEA
 biological_processGO:0048843 negative regulation of axon extension involved in axon guidance IEA
 biological_processGO:0050767 regulation of neurogenesis IMP
 biological_processGO:0060064 Spemann organizer formation at the anterior end of the primitive streak IEA
 biological_processGO:0060070 canonical Wnt signaling pathway TAS
 biological_processGO:0060174 limb bud formation IMP
 biological_processGO:0060323 head morphogenesis IEA
 biological_processGO:0061180 mammary gland epithelium development IEP
 biological_processGO:0071300 cellular response to retinoic acid ISS
 biological_processGO:0072089 stem cell proliferation IMP
 biological_processGO:1904954 canonical Wnt signaling pathway involved in midbrain dopaminergic neuron differentiation IMP
 biological_processGO:1905474 canonical Wnt signaling pathway involved in stem cell proliferation IDA
 cellular_componentGO:0005576 extracellular region TAS
 cellular_componentGO:0005615 extracellular space TAS
 cellular_componentGO:0005788 endoplasmic reticulum lumen TAS
 cellular_componentGO:0005796 Golgi lumen TAS
 cellular_componentGO:0005886 plasma membrane TAS
 cellular_componentGO:0030666 endocytic vesicle membrane TAS
 cellular_componentGO:0070062 extracellular exosome TAS
 cellular_componentGO:1990909 Wnt signalosome NAS
 molecular_functionGO:0005109 frizzled binding IPI
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0019904 protein domain specific binding IEA
 molecular_functionGO:0048018 receptor ligand activity IDA


Pathways (from Reactome)
Pathway description
No match


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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