7474


Homo sapiens (NCBI)

Features
Gene ID: 7474
  
Biological name :
  
Synonyms : hWNT5A / WNT5A / Wnt family member 5A
  
Possible biological names infered from orthology :
  
Species: Homo sapiens (NCBI)
  
Chr. number:
Strand:
Band:
Gene start:
Gene end:
  
Corresponding Affymetrix probe sets: 205990_s_at (Human Genome U133 Plus 2.0 Array)   213425_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: RefSeq - 1034635373
RefSeq - 1034635376
RefSeq - 371502087
RefSeq - 40806205
RefSeq - 578806548
RefSeq - 767924219
RefSeq - 767924221
RefSeq - 767924223
RefSeq - 767924225
RefSeq - 767924227
RefSeq - NC_000003.12
RefSeq - NG_031992.1
RefSeq - NP_001243034.1
RefSeq - NP_003383.2
RefSeq - XP_006713387.1
RefSeq - XP_011532387.1
RefSeq - XP_011532388.1
RefSeq - XP_011532389.1
RefSeq - XP_011532390.1
RefSeq - XP_011532391.1
RefSeq - XP_016862616.1
RefSeq - XP_016862617.1
RefSeq - NM_001256105.1
RefSeq - NM_003392.4
RefSeq - XM_017007127.1
RefSeq - XM_017007128.1
RefSeq - XM_006713324.1
RefSeq - XM_011534085.2
RefSeq - XM_011534086.2
RefSeq - XM_011534087.2
RefSeq - XM_011534088.2
RefSeq - XM_011534089.1
  
See co-cited genes in PubMed
Warning: Please see the Ensembl gene model ENSG00000114251 to get all the annotations available for this gene.


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000187 activation of MAPK activity IDA
 biological_processGO:0001736 establishment of planar polarity IEA
 biological_processGO:0001756 somitogenesis IEA
 biological_processGO:0001837 epithelial to mesenchymal transition IEP
 biological_processGO:0001938 positive regulation of endothelial cell proliferation IMP
 biological_processGO:0001947 heart looping IEA
 biological_processGO:0002053 positive regulation of mesenchymal cell proliferation IEA
 biological_processGO:0002088 lens development in camera-type eye ISS
 biological_processGO:0002741 positive regulation of cytokine secretion involved in immune response IMP
 biological_processGO:0003323 type B pancreatic cell development IEA
 biological_processGO:0003402 planar cell polarity pathway involved in axis elongation IEA
 biological_processGO:0003408 optic cup formation involved in camera-type eye development ISS
 biological_processGO:0007223 Wnt signaling pathway, calcium modulating pathway NAS
 biological_processGO:0007257 activation of JUN kinase activity IMP
 biological_processGO:0007411 axon guidance ISS
 biological_processGO:0007442 hindgut morphogenesis IEA
 biological_processGO:0007494 midgut development IEA
 biological_processGO:0008584 male gonad development IEP
 biological_processGO:0008595 anterior/posterior axis specification, embryo IEA
 biological_processGO:0010033 response to organic substance IEP
 biological_processGO:0010469 regulation of signaling receptor activity IEA
 biological_processGO:0010595 positive regulation of endothelial cell migration IMP
 biological_processGO:0010628 positive regulation of gene expression ISS
 biological_processGO:0010800 positive regulation of peptidyl-threonine phosphorylation IEA
 biological_processGO:0010820 positive regulation of T cell chemotaxis IMP
 biological_processGO:0010976 positive regulation of neuron projection development ISS
 biological_processGO:0016055 Wnt signaling pathway TAS
 biological_processGO:0021891 olfactory bulb interneuron development ISS
 biological_processGO:0030182 neuron differentiation ISS
 biological_processGO:0030216 keratinocyte differentiation IEP
 biological_processGO:0030324 lung development IEA
 biological_processGO:0030514 negative regulation of BMP signaling pathway IEA
 biological_processGO:0032092 positive regulation of protein binding IEA
 biological_processGO:0032148 activation of protein kinase B activity IDA
 biological_processGO:0032729 positive regulation of interferon-gamma production IEA
 biological_processGO:0032755 positive regulation of interleukin-6 production IMP
 biological_processGO:0033138 positive regulation of peptidyl-serine phosphorylation IEA
 biological_processGO:0034613 cellular protein localization IDA
 biological_processGO:0035567 non-canonical Wnt signaling pathway TAS
 biological_processGO:0036342 post-anal tail morphogenesis IEA
 biological_processGO:0036517 chemoattraction of serotonergic neuron axon IEA
 biological_processGO:0036518 chemorepulsion of dopaminergic neuron axon IEA
 biological_processGO:0038031 non-canonical Wnt signaling pathway via JNK cascade IEA
 biological_processGO:0040037 negative regulation of fibroblast growth factor receptor signaling pathway IEA
 biological_processGO:0042060 wound healing IDA
 biological_processGO:0042733 embryonic digit morphogenesis IEA
 biological_processGO:0043032 positive regulation of macrophage activation IMP
 biological_processGO:0043066 negative regulation of apoptotic process IDA
 biological_processGO:0043122 regulation of I-kappaB kinase/NF-kappaB signaling ISS
 biological_processGO:0045080 positive regulation of chemokine biosynthetic process IMP
 biological_processGO:0045165 cell fate commitment IBA
 biological_processGO:0045198 establishment of epithelial cell apical/basal polarity IEA
 biological_processGO:0045599 negative regulation of fat cell differentiation IMP
 biological_processGO:0045732 positive regulation of protein catabolic process IGI
 biological_processGO:0045766 positive regulation of angiogenesis IMP
 biological_processGO:0045778 positive regulation of ossification IMP
 biological_processGO:0045807 positive regulation of endocytosis IEA
 biological_processGO:0045836 positive regulation of meiotic nuclear division IEA
 biological_processGO:0045892 negative regulation of transcription, DNA-templated IDA
 biological_processGO:0045893 positive regulation of transcription, DNA-templated IMP
 biological_processGO:0045944 positive regulation of transcription by RNA polymerase II IMP
 biological_processGO:0048022 negative regulation of melanin biosynthetic process IEA
 biological_processGO:0048146 positive regulation of fibroblast proliferation IDA
 biological_processGO:0048341 paraxial mesoderm formation IEA
 biological_processGO:0048570 notochord morphogenesis IEA
 biological_processGO:0048706 embryonic skeletal system development IMP
 biological_processGO:0048806 genitalia development IMP
 biological_processGO:0048843 negative regulation of axon extension involved in axon guidance IEA
 biological_processGO:0048850 hypophysis morphogenesis IEA
 biological_processGO:0050680 negative regulation of epithelial cell proliferation IEA
 biological_processGO:0050718 positive regulation of interleukin-1 beta secretion ISS
 biological_processGO:0050727 regulation of inflammatory response NAS
 biological_processGO:0050729 positive regulation of inflammatory response IMP
 biological_processGO:0051092 positive regulation of NF-kappaB transcription factor activity IDA
 biological_processGO:0051216 cartilage development IEA
 biological_processGO:0051885 positive regulation of timing of anagen IEA
 biological_processGO:0051964 negative regulation of synapse assembly IEA
 biological_processGO:0060028 convergent extension involved in axis elongation IEA
 biological_processGO:0060029 convergent extension involved in organogenesis IEA
 biological_processGO:0060065 uterus development IEA
 biological_processGO:0060067 cervix development IEA
 biological_processGO:0060068 vagina development IEA
 biological_processGO:0060070 canonical Wnt signaling pathway IEA
 biological_processGO:0060071 Wnt signaling pathway, planar cell polarity pathway TAS
 biological_processGO:0060157 urinary bladder development IEA
 biological_processGO:0060324 face development IMP
 biological_processGO:0060340 positive regulation of type I interferon-mediated signaling pathway IDA
 biological_processGO:0060599 lateral sprouting involved in mammary gland duct morphogenesis IEA
 biological_processGO:0060638 mesenchymal-epithelial cell signaling IEA
 biological_processGO:0060686 negative regulation of prostatic bud formation IEA
 biological_processGO:0060744 mammary gland branching involved in thelarche IEA
 biological_processGO:0060750 epithelial cell proliferation involved in mammary gland duct elongation IEA
 biological_processGO:0060760 positive regulation of response to cytokine stimulus IDA
 biological_processGO:0060762 regulation of branching involved in mammary gland duct morphogenesis IEA
 biological_processGO:0060775 planar cell polarity pathway involved in gastrula mediolateral intercalation IEA
 biological_processGO:0060809 mesodermal to mesenchymal transition involved in gastrulation IEA
 biological_processGO:0060907 positive regulation of macrophage cytokine production IMP
 biological_processGO:0061024 membrane organization TAS
 biological_processGO:0061036 positive regulation of cartilage development IEA
 biological_processGO:0061347 planar cell polarity pathway involved in outflow tract morphogenesis IEA
 biological_processGO:0061348 planar cell polarity pathway involved in ventricular septum morphogenesis IEA
 biological_processGO:0061349 planar cell polarity pathway involved in cardiac right atrium morphogenesis IEA
 biological_processGO:0061350 planar cell polarity pathway involved in cardiac muscle tissue morphogenesis IEA
 biological_processGO:0061354 planar cell polarity pathway involved in pericardium morphogenesis IEA
 biological_processGO:0062009 secondary palate development IMP
 biological_processGO:0070245 positive regulation of thymocyte apoptotic process IEA
 biological_processGO:0071222 cellular response to lipopolysaccharide IEP
 biological_processGO:0071277 cellular response to calcium ion IEP
 biological_processGO:0071300 cellular response to retinoic acid ISS
 biological_processGO:0071346 cellular response to interferon-gamma IEP
 biological_processGO:0071425 hematopoietic stem cell proliferation IDA
 biological_processGO:0071560 cellular response to transforming growth factor beta stimulus IEP
 biological_processGO:0072201 negative regulation of mesenchymal cell proliferation IDA
 biological_processGO:0090009 primitive streak formation IEA
 biological_processGO:0090037 positive regulation of protein kinase C signaling IMP
 biological_processGO:0090090 negative regulation of canonical Wnt signaling pathway IGI
 biological_processGO:0090103 cochlea morphogenesis IEA
 biological_processGO:0090179 planar cell polarity pathway involved in neural tube closure IEA
 biological_processGO:0090263 positive regulation of canonical Wnt signaling pathway IEA
 biological_processGO:0090630 activation of GTPase activity IEA
 biological_processGO:0097325 melanocyte proliferation IEA
 biological_processGO:0099054 presynapse assembly TAS
 biological_processGO:0099068 postsynapse assembly TAS
 biological_processGO:0150012 positive regulation of neuron projection arborization ISS
 biological_processGO:1900020 positive regulation of protein kinase C activity IMP
 biological_processGO:1901216 positive regulation of neuron death ISS
 biological_processGO:1902474 positive regulation of protein localization to synapse TAS
 biological_processGO:1903827 regulation of cellular protein localization IEA
 biological_processGO:1904469 positive regulation of tumor necrosis factor secretion ISS
 biological_processGO:1904861 excitatory synapse assembly TAS
 biological_processGO:1904862 inhibitory synapse assembly TAS
 biological_processGO:1904934 negative regulation of cell proliferation in midbrain NAS
 biological_processGO:1904938 planar cell polarity pathway involved in axon guidance IEA
 biological_processGO:1904953 Wnt signaling pathway involved in midbrain dopaminergic neuron differentiation NAS
 biological_processGO:1904955 planar cell polarity pathway involved in midbrain dopaminergic neuron differentiation TAS
 biological_processGO:2000049 positive regulation of cell-cell adhesion mediated by cadherin IEA
 biological_processGO:2000052 positive regulation of non-canonical Wnt signaling pathway IEA
 biological_processGO:2000484 positive regulation of interleukin-8 secretion IEA
 cellular_componentGO:0005576 extracellular region TAS
 cellular_componentGO:0005615 extracellular space IDA
 cellular_componentGO:0005788 endoplasmic reticulum lumen TAS
 cellular_componentGO:0005796 Golgi lumen TAS
 cellular_componentGO:0005886 plasma membrane TAS
 cellular_componentGO:0009986 cell surface IEA
 cellular_componentGO:0030665 clathrin-coated vesicle membrane TAS
 cellular_componentGO:0030666 endocytic vesicle membrane TAS
 cellular_componentGO:0030669 clathrin-coated endocytic vesicle membrane TAS
 cellular_componentGO:0070062 extracellular exosome TAS
 molecular_functionGO:0003700 DNA-binding transcription factor activity IMP
 molecular_functionGO:0005109 frizzled binding TAS
 molecular_functionGO:0005115 receptor tyrosine kinase-like orphan receptor binding IPI
 molecular_functionGO:0005125 cytokine activity IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0005543 phospholipid binding TAS
 molecular_functionGO:0019904 protein domain specific binding IEA
 molecular_functionGO:0044212 transcription regulatory region DNA binding IDA
 molecular_functionGO:0048018 receptor ligand activity IC
 molecular_functionGO:1902379 chemoattractant activity involved in axon guidance IEA


Pathways (from Reactome)
Pathway description
No match


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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