7520


Homo sapiens (NCBI)

Features
Gene ID: 7520
  
Biological name :
  
Synonyms : KARP-1|KARP1|KU80|KUB2|Ku86|NFIV / X-ray repair cross complementing 5 / XRCC5
  
Possible biological names infered from orthology :
  
Species: Homo sapiens (NCBI)
  
Chr. number:
Strand:
Band:
Gene start:
Gene end:
  
Corresponding Affymetrix probe sets: 208642_s_at (Human Genome U133 Plus 2.0 Array)   208643_s_at (Human Genome U133 Plus 2.0 Array)   232633_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: RefSeq - 10863945
RefSeq - NC_000002.12
RefSeq - NG_029780.1
RefSeq - NP_066964.1
RefSeq - NM_021141.3
  
See co-cited genes in PubMed
Warning: Please see the Ensembl gene model ENSG00000079246 to get all the annotations available for this gene.


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000723 telomere maintenance IEA
 biological_processGO:0002218 activation of innate immune response IDA
 biological_processGO:0006302 double-strand break repair IMP
 biological_processGO:0006303 double-strand break repair via nonhomologous end joining TAS
 biological_processGO:0006310 DNA recombination IEA
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0007420 brain development IEA
 biological_processGO:0008283 cell proliferation IEA
 biological_processGO:0032204 regulation of telomere maintenance TAS
 biological_processGO:0032212 positive regulation of telomere maintenance via telomerase IMP
 biological_processGO:0032481 positive regulation of type I interferon production TAS
 biological_processGO:0032508 DNA duplex unwinding IEA
 biological_processGO:0042493 response to drug IEA
 biological_processGO:0043085 positive regulation of catalytic activity TAS
 biological_processGO:0043312 neutrophil degranulation TAS
 biological_processGO:0045087 innate immune response IEA
 biological_processGO:0045860 positive regulation of protein kinase activity IDA
 biological_processGO:0045892 negative regulation of transcription, DNA-templated IMP
 biological_processGO:0048660 regulation of smooth muscle cell proliferation IMP
 biological_processGO:0050769 positive regulation of neurogenesis IEA
 biological_processGO:0051973 positive regulation of telomerase activity TAS
 biological_processGO:0060218 hematopoietic stem cell differentiation IEA
 biological_processGO:0070198 protein localization to chromosome, telomeric region TAS
 biological_processGO:0071398 cellular response to fatty acid IEA
 biological_processGO:0071475 cellular hyperosmotic salinity response IEA
 biological_processGO:0071480 cellular response to gamma radiation IDA
 biological_processGO:0071481 cellular response to X-ray IEA
 biological_processGO:0075713 establishment of integrated proviral latency TAS
 biological_processGO:1904430 negative regulation of t-circle formation IMP
 biological_processGO:1990830 cellular response to leukemia inhibitory factor IEA
 cellular_componentGO:0000783 nuclear telomere cap complex TAS
 cellular_componentGO:0000784 nuclear chromosome, telomeric region IDA
 cellular_componentGO:0005576 extracellular region TAS
 cellular_componentGO:0005634 nucleus IDA
 cellular_componentGO:0005654 nucleoplasm TAS
 cellular_componentGO:0005730 nucleolus IEA
 cellular_componentGO:0005829 cytosol TAS
 cellular_componentGO:0005886 plasma membrane IDA
 cellular_componentGO:0016020 membrane HDA
 cellular_componentGO:0032991 protein-containing complex IDA
 cellular_componentGO:0032993 protein-DNA complex IDA
 cellular_componentGO:0034774 secretory granule lumen TAS
 cellular_componentGO:0043564 Ku70:Ku80 complex TAS
 cellular_componentGO:0070419 nonhomologous end joining complex IDA
 cellular_componentGO:1990904 ribonucleoprotein complex IDA
 molecular_functionGO:0003677 DNA binding NAS
 molecular_functionGO:0003684 damaged DNA binding IEA
 molecular_functionGO:0003690 double-stranded DNA binding TAS
 molecular_functionGO:0003691 double-stranded telomeric DNA binding IDA
 molecular_functionGO:0003723 RNA binding IDA
 molecular_functionGO:0004003 ATP-dependent DNA helicase activity IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0008022 protein C-terminus binding IPI
 molecular_functionGO:0008047 enzyme activator activity TAS
 molecular_functionGO:0031625 ubiquitin protein ligase binding IPI
 molecular_functionGO:0042162 telomeric DNA binding TAS
 molecular_functionGO:0044212 transcription regulatory region DNA binding IDA
 molecular_functionGO:0044877 protein-containing complex binding IPI
 molecular_functionGO:0051575 5"-deoxyribose-5-phosphate lyase activity IMP


Pathways (from Reactome)
Pathway description
No match


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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