78943


Mus musculus (NCBI)

Features
Gene ID: 78943
  
Biological name :
  
Synonyms : 9030414B18Rik|AI225830|C85377|Ire1a|Ire1alpha|Ire1p / endoplasmic reticulum (ER) to nucleus signalling 1 / Ern1
  
Possible biological names infered from orthology :
  
Species: Mus musculus (NCBI)
  
Chr. number:
Strand:
Band:
Gene start:
Gene end:
  
Corresponding Affymetrix probe sets: 1421240_at (Mouse Genome 430 2.0 Array)   1431886_at (Mouse Genome 430 2.0 Array)   1437119_at (Mouse Genome 430 2.0 Array)   1438583_at (Mouse Genome 430 2.0 Array)   1450176_at (Mouse Genome 430 2.0 Array)   
  
Cross references: RefSeq - 13249351
RefSeq - NC_000077.6
RefSeq - NP_076402.1
RefSeq - NM_023913.2
  
See co-cited genes in PubMed
Warning: Please see the Ensembl gene model ENSMUSG00000020715 to get all the annotations available for this gene.


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001935 endothelial cell proliferation ISO
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0006379 mRNA cleavage IDA
 biological_processGO:0006397 mRNA processing IEA
 biological_processGO:0006468 protein phosphorylation ISO
 biological_processGO:0006915 apoptotic process IEA
 biological_processGO:0006986 response to unfolded protein IEA
 biological_processGO:0007050 cell cycle arrest IDA
 biological_processGO:0007257 activation of JUN kinase activity ISO
 biological_processGO:0008152 metabolic process IEA
 biological_processGO:0016310 phosphorylation IEA
 biological_processGO:0030968 endoplasmic reticulum unfolded protein response IDA
 biological_processGO:0033120 positive regulation of RNA splicing ISO
 biological_processGO:0034620 cellular response to unfolded protein ISO
 biological_processGO:0034976 response to endoplasmic reticulum stress ISO
 biological_processGO:0035924 cellular response to vascular endothelial growth factor stimulus ISO
 biological_processGO:0036289 peptidyl-serine autophosphorylation ISO
 biological_processGO:0036498 IRE1-mediated unfolded protein response ISO
 biological_processGO:0046777 protein autophosphorylation ISO
 biological_processGO:0070054 mRNA splicing, via endonucleolytic cleavage and ligation ISO
 biological_processGO:0070059 intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress IMP
 biological_processGO:0071333 cellular response to glucose stimulus ISO
 biological_processGO:0098787 mRNA cleavage involved in mRNA processing ISO
 biological_processGO:1900103 positive regulation of endoplasmic reticulum unfolded protein response ISO
 biological_processGO:1901142 insulin metabolic process ISO
 biological_processGO:1904707 positive regulation of vascular smooth muscle cell proliferation ISO
 biological_processGO:1990579 peptidyl-serine trans-autophosphorylation ISO
 cellular_componentGO:0005637 nuclear inner membrane IDA
 cellular_componentGO:0005737 cytoplasm ISO
 cellular_componentGO:0005739 mitochondrion IDA
 cellular_componentGO:0005783 endoplasmic reticulum ISO
 cellular_componentGO:0005789 endoplasmic reticulum membrane IDA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0030176 integral component of endoplasmic reticulum membrane ISO
 cellular_componentGO:1990597 AIP1-IRE1 complex IPI
 cellular_componentGO:1990604 IRE1-TRAF2-ASK1 complex ISO
 cellular_componentGO:1990630 IRE1-RACK1-PP2A complex ISO
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0000287 magnesium ion binding ISO
 molecular_functionGO:0003824 catalytic activity IEA
 molecular_functionGO:0004519 endonuclease activity IDA
 molecular_functionGO:0004521 endoribonuclease activity ISO
 molecular_functionGO:0004540 ribonuclease activity IEA
 molecular_functionGO:0004672 protein kinase activity IEA
 molecular_functionGO:0004674 protein serine/threonine kinase activity ISO
 molecular_functionGO:0005161 platelet-derived growth factor receptor binding ISO
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0005524 ATP binding ISO
 molecular_functionGO:0016301 kinase activity IEA
 molecular_functionGO:0016740 transferase activity IEA
 molecular_functionGO:0016787 hydrolase activity IEA
 molecular_functionGO:0019899 enzyme binding ISO
 molecular_functionGO:0030544 Hsp70 protein binding ISO
 molecular_functionGO:0042802 identical protein binding ISO
 molecular_functionGO:0042803 protein homodimerization activity ISO
 molecular_functionGO:0043531 ADP binding ISO
 molecular_functionGO:0046872 metal ion binding IEA
 molecular_functionGO:0051879 Hsp90 protein binding ISO


Pathways (from Reactome)
Pathway description
No match


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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