834


Homo sapiens (NCBI)

Features
Gene ID: 834
  
Biological name :
  
Synonyms : CASP1 / caspase 1 / ICE|IL1BC|P45
  
Possible biological names infered from orthology :
  
Species: Homo sapiens (NCBI)
  
Chr. number:
Strand:
Band:
Gene start:
Gene end:
  
Corresponding Affymetrix probe sets: 1552703_s_at (Human Genome U133 Plus 2.0 Array)   206011_at (Human Genome U133 Plus 2.0 Array)   209970_x_at (Human Genome U133 Plus 2.0 Array)   211366_x_at (Human Genome U133 Plus 2.0 Array)   211367_s_at (Human Genome U133 Plus 2.0 Array)   211368_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: RefSeq - 1034575743
RefSeq - 1034575745
RefSeq - 1034575747
RefSeq - 1034575749
RefSeq - 15431328
RefSeq - 15431330
RefSeq - 15431332
RefSeq - 15431334
RefSeq - 380254457
RefSeq - 380254459
RefSeq - 4502573
RefSeq - NC_000011.10
RefSeq - NG_029124.1
RefSeq - NP_001214.1
RefSeq - NP_001244047.1
RefSeq - NP_001244048.1
RefSeq - NP_150634.1
RefSeq - NP_150635.1
RefSeq - NP_150636.1
RefSeq - NP_150637.1
RefSeq - XP_016873882.1
RefSeq - XP_016873883.1
RefSeq - XP_016873884.1
RefSeq - XP_016873885.1
RefSeq - NM_001223.4
RefSeq - NM_001257118.2
RefSeq - NM_001257119.2
RefSeq - NM_033292.3
RefSeq - NM_033293.3
RefSeq - NM_033294.3
RefSeq - NM_033295.3
RefSeq - XM_017018394.1
RefSeq - XM_017018395.1
RefSeq - XM_017018396.1
RefSeq - XM_017018393.1
  
See co-cited genes in PubMed
Warning: Please see the Ensembl gene model ENSG00000137752 to get all the annotations available for this gene.


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001666 response to hypoxia IEA
 biological_processGO:0006508 proteolysis IDA
 biological_processGO:0006915 apoptotic process TAS
 biological_processGO:0006919 activation of cysteine-type endopeptidase activity involved in apoptotic process IEA
 biological_processGO:0007165 signal transduction TAS
 biological_processGO:0010506 regulation of autophagy IEA
 biological_processGO:0016540 protein autoprocessing IDA
 biological_processGO:0019221 cytokine-mediated signaling pathway TAS
 biological_processGO:0032611 interleukin-1 beta production IEA
 biological_processGO:0033198 response to ATP IEA
 biological_processGO:0042981 regulation of apoptotic process TAS
 biological_processGO:0043123 positive regulation of I-kappaB kinase/NF-kappaB signaling IMP
 biological_processGO:0043280 positive regulation of cysteine-type endopeptidase activity involved in apoptotic process IMP
 biological_processGO:0050717 positive regulation of interleukin-1 alpha secretion IEA
 biological_processGO:0050718 positive regulation of interleukin-1 beta secretion IMP
 biological_processGO:0051882 mitochondrial depolarization IEA
 biological_processGO:0060081 membrane hyperpolarization IEA
 biological_processGO:0070269 pyroptosis IEA
 biological_processGO:0071222 cellular response to lipopolysaccharide IMP
 biological_processGO:0071260 cellular response to mechanical stimulus IEP
 biological_processGO:0071310 cellular response to organic substance IDA
 biological_processGO:0071345 cellular response to cytokine stimulus TAS
 biological_processGO:0071346 cellular response to interferon-gamma IMP
 biological_processGO:0097194 execution phase of apoptosis IBA
 biological_processGO:0097300 programmed necrotic cell death IEA
 biological_processGO:1901998 toxin transport IEA
 biological_processGO:1903265 positive regulation of tumor necrosis factor-mediated signaling pathway IMP
 cellular_componentGO:0005576 extracellular region IEA
 cellular_componentGO:0005737 cytoplasm IBA
 cellular_componentGO:0005739 mitochondrion IEA
 cellular_componentGO:0005829 cytosol TAS
 cellular_componentGO:0032991 protein-containing complex IMP
 cellular_componentGO:0072557 IPAF inflammasome complex ISS
 cellular_componentGO:0072558 NLRP1 inflammasome complex IDA
 cellular_componentGO:0072559 NLRP3 inflammasome complex IDA
 cellular_componentGO:0097169 AIM2 inflammasome complex IDA
 cellular_componentGO:0097179 protease inhibitor complex IMP
 molecular_functionGO:0004175 endopeptidase activity IDA
 molecular_functionGO:0004197 cysteine-type endopeptidase activity TAS
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0008656 cysteine-type endopeptidase activator activity involved in apoptotic process TAS
 molecular_functionGO:0019900 kinase binding IPI
 molecular_functionGO:0042802 identical protein binding IPI
 molecular_functionGO:0050700 CARD domain binding IPI
 molecular_functionGO:0097153 cysteine-type endopeptidase activity involved in apoptotic process IBA
 molecular_functionGO:0097199 cysteine-type endopeptidase activity involved in apoptotic signaling pathway IBA
 molecular_functionGO:0097200 cysteine-type endopeptidase activity involved in execution phase of apoptosis IBA


Pathways (from Reactome)
Pathway description
No match


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

0 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2024
contact: otassy@igbmc.fr