83737


Homo sapiens (NCBI)

Features
Gene ID: 83737
  
Biological name :
  
Synonyms : ADMFD|AIF4|AIP4|NAPP1 / ITCH / itchy E3 ubiquitin protein ligase
  
Possible biological names infered from orthology :
  
Species: Homo sapiens (NCBI)
  
Chr. number:
Strand:
Band:
Gene start:
Gene end:
  
Corresponding Affymetrix probe sets: 209743_s_at (Human Genome U133 Plus 2.0 Array)   209744_x_at (Human Genome U133 Plus 2.0 Array)   217094_s_at (Human Genome U133 Plus 2.0 Array)   235057_at (Human Genome U133 Plus 2.0 Array)   236235_at (Human Genome U133 Plus 2.0 Array)   239101_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: RefSeq - 1023300941
RefSeq - 1023300970
RefSeq - 1034625912
RefSeq - 1034625914
RefSeq - 1034625916
RefSeq - 1034625919
RefSeq - 1370481000
RefSeq - 27477109
RefSeq - 380420335
RefSeq - 380420338
RefSeq - 530418435
RefSeq - 768018465
RefSeq - NC_000020.11
RefSeq - NG_023206.1
RefSeq - NP_001244066.1
RefSeq - NP_001244067.1
RefSeq - NP_001311126.1
RefSeq - NP_001311127.1
RefSeq - NP_113671.3
RefSeq - XP_005260627.1
RefSeq - XP_011527381.1
RefSeq - XP_016883578.1
RefSeq - XP_016883579.1
RefSeq - XP_016883580.1
RefSeq - XP_016883581.1
RefSeq - XP_024307773.1
RefSeq - XM_017028089.1
RefSeq - NM_001257137.2
RefSeq - NM_001257138.2
RefSeq - NM_001324197.1
RefSeq - NM_001324198.1
RefSeq - NM_031483.6
RefSeq - XM_017028090.1
RefSeq - XM_017028091.1
RefSeq - XM_017028092.2
RefSeq - XM_024452005.1
RefSeq - XR_001754418.1
RefSeq - XM_005260570.1
RefSeq - XM_011529079.1
  
See co-cited genes in PubMed
Warning: Please see the Ensembl gene model ENSG00000078747 to get all the annotations available for this gene.


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000209 protein polyubiquitination IBA
 biological_processGO:0001558 regulation of cell growth NAS
 biological_processGO:0002669 positive regulation of T cell anergy IEA
 biological_processGO:0006511 ubiquitin-dependent protein catabolic process NAS
 biological_processGO:0006915 apoptotic process IEA
 biological_processGO:0006954 inflammatory response NAS
 biological_processGO:0007219 Notch signaling pathway TAS
 biological_processGO:0016567 protein ubiquitination IMP
 biological_processGO:0032088 negative regulation of NF-kappaB transcription factor activity ISS
 biological_processGO:0032480 negative regulation of type I interferon production TAS
 biological_processGO:0035519 protein K29-linked ubiquitination IDA
 biological_processGO:0043066 negative regulation of apoptotic process IMP
 biological_processGO:0043161 proteasome-mediated ubiquitin-dependent protein catabolic process IBA
 biological_processGO:0045087 innate immune response IEA
 biological_processGO:0045732 positive regulation of protein catabolic process IEA
 biological_processGO:0046329 negative regulation of JNK cascade ISS
 biological_processGO:0046642 negative regulation of alpha-beta T cell proliferation IEA
 biological_processGO:0046718 viral entry into host cell TAS
 biological_processGO:0050687 negative regulation of defense response to virus IMP
 biological_processGO:0051607 defense response to virus IEA
 biological_processGO:0051865 protein autoubiquitination IMP
 biological_processGO:0070423 nucleotide-binding oligomerization domain containing signaling pathway TAS
 biological_processGO:0070534 protein K63-linked ubiquitination IDA
 biological_processGO:0070936 protein K48-linked ubiquitination IDA
 biological_processGO:0090085 regulation of protein deubiquitination ISS
 biological_processGO:1902036 regulation of hematopoietic stem cell differentiation TAS
 biological_processGO:2000646 positive regulation of receptor catabolic process IMP
 cellular_componentGO:0005654 nucleoplasm IDA
 cellular_componentGO:0005737 cytoplasm IBA
 cellular_componentGO:0005769 early endosome IDA
 cellular_componentGO:0005829 cytosol TAS
 cellular_componentGO:0005886 plasma membrane IDA
 cellular_componentGO:0005938 cell cortex IEA
 cellular_componentGO:0016020 membrane HDA
 cellular_componentGO:0031901 early endosome membrane IEA
 cellular_componentGO:0032991 protein-containing complex IDA
 cellular_componentGO:0043231 intracellular membrane-bounded organelle IDA
 cellular_componentGO:0070062 extracellular exosome HDA
 molecular_functionGO:0004842 ubiquitin-protein transferase activity NAS
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0016874 ligase activity IEA
 molecular_functionGO:0019787 ubiquitin-like protein transferase activity TAS
 molecular_functionGO:0043021 ribonucleoprotein complex binding IPI
 molecular_functionGO:0044389 ubiquitin-like protein ligase binding IPI
 molecular_functionGO:0045236 CXCR chemokine receptor binding IPI
 molecular_functionGO:0061630 ubiquitin protein ligase activity TAS
 molecular_functionGO:1990763 arrestin family protein binding IPI


Pathways (from Reactome)
Pathway description
No match


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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