8440


Homo sapiens (NCBI)

Features
Gene ID: 8440
  
Biological name :
  
Synonyms : GRB4|NCKbeta / NCK2 / NCK adaptor protein 2
  
Possible biological names infered from orthology :
  
Species: Homo sapiens (NCBI)
  
Chr. number:
Strand:
Band:
Gene start:
Gene end:
  
Corresponding Affymetrix probe sets: 203315_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: RefSeq - XP_016860594.1
RefSeq - 1034617125
RefSeq - 1034617127
RefSeq - 1034617130
RefSeq - 52630423
RefSeq - 52630425
RefSeq - 52630427
RefSeq - 578805023
RefSeq - 767920137
RefSeq - NC_000002.12
RefSeq - NP_001004720.1
RefSeq - NP_001004722.1
RefSeq - NP_003572.2
RefSeq - XP_006712860.1
RefSeq - XP_011510293.1
RefSeq - XP_011510294.2
RefSeq - XP_016860592.1
RefSeq - XP_016860593.1
RefSeq - 1034617123
RefSeq - NM_001004720.2
RefSeq - NM_001004722.3
RefSeq - NM_003581.4
RefSeq - XM_017005103.1
RefSeq - XM_017005104.1
RefSeq - XM_017005105.1
RefSeq - XM_006712797.3
RefSeq - XM_011511991.3
RefSeq - XM_011511992.2
  
See co-cited genes in PubMed
Warning: Please see the Ensembl gene model ENSG00000071051 to get all the annotations available for this gene.


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001771 immunological synapse formation IEA
 biological_processGO:0007015 actin filament organization IEA
 biological_processGO:0007165 signal transduction TAS
 biological_processGO:0007172 signal complex assembly NAS
 biological_processGO:0007173 epidermal growth factor receptor signaling pathway TAS
 biological_processGO:0007176 regulation of epidermal growth factor-activated receptor activity TAS
 biological_processGO:0008285 negative regulation of cell proliferation TAS
 biological_processGO:0016477 cell migration IEA
 biological_processGO:0030032 lamellipodium assembly IEA
 biological_processGO:0030838 positive regulation of actin filament polymerization IMP
 biological_processGO:0033137 negative regulation of peptidyl-serine phosphorylation IDA
 biological_processGO:0036493 positive regulation of translation in response to endoplasmic reticulum stress IEA
 biological_processGO:0042102 positive regulation of T cell proliferation IMP
 biological_processGO:0042110 T cell activation NAS
 biological_processGO:0045944 positive regulation of transcription by RNA polymerase II IDA
 biological_processGO:0048010 vascular endothelial growth factor receptor signaling pathway TAS
 biological_processGO:0048013 ephrin receptor signaling pathway TAS
 biological_processGO:0060996 dendritic spine development IEA
 biological_processGO:1902237 positive regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway IEA
 biological_processGO:1903898 negative regulation of PERK-mediated unfolded protein response IEA
 biological_processGO:1903912 negative regulation of endoplasmic reticulum stress-induced eIF2 alpha phosphorylation IDA
 biological_processGO:1990441 negative regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress IEA
 cellular_componentGO:0005737 cytoplasm NAS
 cellular_componentGO:0005783 endoplasmic reticulum IDA
 cellular_componentGO:0005829 cytosol TAS
 cellular_componentGO:0012506 vesicle membrane IEA
 cellular_componentGO:0014069 postsynaptic density IEA
 molecular_functionGO:0001784 phosphotyrosine residue binding IPI
 molecular_functionGO:0005070 SH3/SH2 adaptor activity NAS
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0008093 cytoskeletal adaptor activity NAS
 molecular_functionGO:0030159 receptor signaling complex scaffold activity NAS
 molecular_functionGO:0044877 protein-containing complex binding IEA
 molecular_functionGO:0097110 scaffold protein binding IEA


Pathways (from Reactome)
Pathway description
No match


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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