8463


Homo sapiens (NCBI)
transcriptionbindingfactorregulationrnapolymeraseiiactivitydevelopmentcomplexsequence-specificdnatubeembryonicdna-templatedmesodermcellproteinvasculogenesisneuralclosureheartmorphogenesisinitiationpromoternotochordhipposignalingparaxiallateral

Features
Gene ID: 8463
  
Biological name :
  
Synonyms : ETF|TEAD-2|TEF-4|TEF4 / TEAD2 / TEA domain transcription factor 2
  
Possible biological names infered from orthology :
  
Species: Homo sapiens (NCBI)
  
Chr. number:
Strand:
Band:
Gene start:
Gene end:
  
Corresponding Affymetrix probe sets: 226408_at (Human Genome U133 Plus 2.0 Array)   238322_s_at (Human Genome U133 Plus 2.0 Array)   238323_at (Human Genome U133 Plus 2.0 Array)   243766_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: RefSeq - 768011567
RefSeq - 375331913
RefSeq - 375331915
RefSeq - 375331918
RefSeq - 375331920
RefSeq - 375331923
RefSeq - 530417413
RefSeq - 578835013
RefSeq - 578835016
RefSeq - 768011555
RefSeq - 768011559
RefSeq - 768011563
RefSeq - 20070103
RefSeq - 768011572
RefSeq - 768011576
RefSeq - 768011585
RefSeq - 768011587
RefSeq - NC_000019.10
RefSeq - NP_001243587.1
RefSeq - NP_001243588.1
RefSeq - NP_001243589.1
RefSeq - NP_001243590.1
RefSeq - NP_001243591.1
RefSeq - NP_003589.1
RefSeq - XP_005259391.1
RefSeq - XP_006723491.1
RefSeq - XP_006723492.1
RefSeq - XP_011525701.1
RefSeq - XP_011525702.1
RefSeq - XP_011525703.1
RefSeq - XP_011525704.1
RefSeq - XP_011525705.1
RefSeq - XP_011525706.1
RefSeq - XP_011525707.1
RefSeq - XP_011525708.1
RefSeq - NM_001256658.1
RefSeq - NM_001256659.1
RefSeq - NM_001256660.1
RefSeq - NM_001256661.1
RefSeq - NM_001256662.1
RefSeq - NM_003598.1
RefSeq - XM_011527401.1
RefSeq - XM_011527402.2
RefSeq - XM_011527403.1
RefSeq - XM_011527404.2
RefSeq - XM_011527405.3
RefSeq - XM_011527406.3
RefSeq - XM_005259334.4
RefSeq - XM_006723428.3
RefSeq - XM_006723429.2
RefSeq - XM_011527399.2
RefSeq - XM_011527400.2
  
See co-cited genes in PubMed
Warning: Please see the Ensembl gene model ENSG00000074219 to get all the annotations available for this gene.


Gene Ontology (GO)
anatomical structure developmentcellular developmental processnitrogen compound metabolic processbiosynthetic processcellular metabolic processprimary metabolic processorganic substance metabolic processcell communicationcellular response to stimuluscell deathcellular component organizationcellular component biogenesisresponse to chemicalanatomical structure developmentcellular developmental processnitrogen compound metabolic processbiosynthetic processcellular metabolic processprimary metabolic processorganic substance metabolic processcell communicationcellular response to stimuluscell deathcellular component organizationcellular component biogenesisresponse to chemicalanatomical structure developmentcellular developmental processnitrogen compound metabolic processbiosynthetic processcellular metabolic processprimary metabolic processorganic substance metabolic processcell communicationcellular response to stimuluscell deathcellular component organizationcellular component biogenesisresponse to chemicalanatomical structure developmentcellular developmental processnitrogen compound metabolic processbiosynthetic processcellular metabolic processprimary metabolic processorganic substance metabolic processcell communicationcellular response to stimuluscell deathcellular component organizationcellular component biogenesisresponse to chemicalanatomical structure developmentcellular developmental processnitrogen compound metabolic processbiosynthetic processcellular metabolic processprimary metabolic processorganic substance metabolic processcell communicationcellular response to stimuluscell deathcellular component organizationcellular component biogenesisresponse to chemicalanatomical structure developmentcellular developmental processnitrogen compound metabolic processbiosynthetic processcellular metabolic processprimary metabolic processorganic substance metabolic processcell communicationcellular response to stimuluscell deathcellular component organizationcellular component biogenesisresponse to chemicalanatomical structure developmentcellular developmental processnitrogen compound metabolic processbiosynthetic processcellular metabolic processprimary metabolic processorganic substance metabolic processcell communicationcellular response to stimuluscell deathcellular component organizationcellular component biogenesisresponse to chemicalanatomical structure developmentcellular developmental processnitrogen compound metabolic processbiosynthetic processcellular metabolic processprimary metabolic processorganic substance metabolic processcell communicationcellular response to stimuluscell deathcellular component organizationcellular component biogenesisresponse to chemicalanatomical structure developmentcellular developmental processnitrogen compound metabolic processbiosynthetic processcellular metabolic processprimary metabolic processorganic substance metabolic processcell communicationcellular response to stimuluscell deathcellular component organizationcellular component biogenesisresponse to chemicalanatomical structure developmentcellular developmental processnitrogen compound metabolic processbiosynthetic processcellular metabolic processprimary metabolic processorganic substance metabolic processcell communicationcellular response to stimuluscell deathcellular component organizationcellular component biogenesisresponse to chemicalanatomicalanatomical structure developmentcellular dcellular developmental processnitrogen cnitrogen compound metabolic processbiosynthetbiosynthetic processcellular mcellular metabolic processprimary meprimary metabolic processorganic suorganic substance metabolic processcell commucell communicationcellular rcellular response to stimuluscell deathcell deathcellular ccellular component organizationcellular ccellular component biogenesisresponse tresponse to chemical
DNA-binding transcription factor activityprotein bindingtranscription factor activity, protein bindingorganic cyclic compound bindingheterocyclic compound bindingDNA-binding transcription factor activityprotein bindingtranscription factor activity, protein bindingorganic cyclic compound bindingheterocyclic compound bindingDNA-binding transcription factor activityprotein bindingtranscription factor activity, protein bindingorganic cyclic compound bindingheterocyclic compound bindingDNA-binding transcription factor activityprotein bindingtranscription factor activity, protein bindingorganic cyclic compound bindingheterocyclic compound bindingDNA-binding transcription factor activityprotein bindingtranscription factor activity, protein bindingorganic cyclic compound bindingheterocyclic compound bindingDNA-binding transcription factor activityprotein bindingtranscription factor activity, protein bindingorganic cyclic compound bindingheterocyclic compound bindingDNA-binding transcription factor activityprotein bindingtranscription factor activity, protein bindingorganic cyclic compound bindingheterocyclic compound bindingDNA-binding transcription factor activityprotein bindingtranscription factor activity, protein bindingorganic cyclic compound bindingheterocyclic compound bindingDNA-binding transcription factor activityprotein bindingtranscription factor activity, protein bindingorganic cyclic compound bindingheterocyclic compound bindingDNA-binding transcription factor activityprotein bindingtranscription factor activity, protein bindingorganic cyclic compound bindingheterocyclic compound bindingDNA-binding transcription faDNA-binding transcription factor activityprotein bindingprotein bindingtranscription factor activittranscription factor activity, protein bindingorganic cyclic compound bindorganic cyclic compound bindingheterocyclic compound bindinheterocyclic compound binding
cellorganellemembrane-enclosed lumenprotein-containing complexcellorganellemembrane-enclosed lumenprotein-containing complexcellorganellemembrane-enclosed lumenprotein-containing complexcellorganellemembrane-enclosed lumenprotein-containing complexcellorganellemembrane-enclosed lumenprotein-containing complexcellorganellemembrane-enclosed lumenprotein-containing complexcellorganellemembrane-enclosed lumenprotein-containing complexcellorganellemembrane-enclosed lumenprotein-containing complexcellorganellemembrane-enclosed lumenprotein-containing complexcellorganellemembrane-enclosed lumenprotein-containing complexcellcellorganelleorganellemembrane-enclosed lumenmembrane-enclosed lumenprotein-containing complexprotein-containing complex
TypeGO IDTermEv.Code
 biological_processGO:0001570 vasculogenesis IEA
 biological_processGO:0001843 neural tube closure IEA
 biological_processGO:0003143 embryonic heart tube morphogenesis IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated NAS
 biological_processGO:0006367 transcription initiation from RNA polymerase II promoter TAS
 biological_processGO:0030903 notochord development IEA
 biological_processGO:0035329 hippo signaling IDA
 biological_processGO:0045893 positive regulation of transcription, DNA-templated IMP
 biological_processGO:0045944 positive regulation of transcription by RNA polymerase II IBA
 biological_processGO:0048339 paraxial mesoderm development IEA
 biological_processGO:0048368 lateral mesoderm development IEA
 biological_processGO:0048568 embryonic organ development IBA
 biological_processGO:0060548 negative regulation of cell death IEA
 biological_processGO:0065003 protein-containing complex assembly IMP
 biological_processGO:0071300 cellular response to retinoic acid IEA
 biological_processGO:2000736 regulation of stem cell differentiation IEA
 cellular_componentGO:0005634 nucleus NAS
 cellular_componentGO:0005654 nucleoplasm TAS
 cellular_componentGO:0005667 transcription factor complex IBA
 cellular_componentGO:0005829 cytosol IDA
 cellular_componentGO:0043231 intracellular membrane-bounded organelle IDA
 cellular_componentGO:0071149 TEAD-2-YAP complex IDA
 molecular_functionGO:0000981 RNA polymerase II transcription factor activity, sequence-specific DNA binding NAS
 molecular_functionGO:0001085 RNA polymerase II transcription factor binding IBA
 molecular_functionGO:0001134 transcription factor activity, transcription factor recruiting IMP
 molecular_functionGO:0001223 transcription coactivator binding IPI
 molecular_functionGO:0003700 DNA-binding transcription factor activity NAS
 molecular_functionGO:0003705 transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0043565 sequence-specific DNA binding IBA
 molecular_functionGO:0044212 transcription regulatory region DNA binding IBA
 molecular_functionGO:0046982 protein heterodimerization activity IPI
 molecular_functionGO:0097718 disordered domain specific binding IMP


Pathways (from Reactome)
Pathway description
No match


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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