84868


Homo sapiens (NCBI)

Features
Gene ID: 84868
  
Biological name :
  
Synonyms : CD366|HAVcr-2|KIM-3|TIM3|TIMD-3|TIMD3|Tim-3 / HAVCR2 / hepatitis A virus cellular receptor 2
  
Possible biological names infered from orthology :
  
Species: Homo sapiens (NCBI)
  
Chr. number:
Strand:
Band:
Gene start:
Gene end:
  
Corresponding Affymetrix probe sets: 1554285_at (Human Genome U133 Plus 2.0 Array)   1555628_a_at (Human Genome U133 Plus 2.0 Array)   1555629_at (Human Genome U133 Plus 2.0 Array)   235458_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: RefSeq - 49574534
RefSeq - NC_000005.10
RefSeq - NG_030444.1
RefSeq - NP_116171.3
RefSeq - NM_032782.4
  
See co-cited genes in PubMed
Warning: Please see the Ensembl gene model ENSG00000135077 to get all the annotations available for this gene.


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0002250 adaptive immune response IEA
 biological_processGO:0002281 macrophage activation involved in immune response IEA
 biological_processGO:0002519 natural killer cell tolerance induction IMP
 biological_processGO:0002652 regulation of tolerance induction dependent upon immune response IEA
 biological_processGO:0002826 negative regulation of T-helper 1 type immune response IEA
 biological_processGO:0002859 negative regulation of natural killer cell mediated cytotoxicity directed against tumor cell target IEA
 biological_processGO:0006357 regulation of transcription by RNA polymerase II IBA
 biological_processGO:0006954 inflammatory response IEA
 biological_processGO:0010629 negative regulation of gene expression IMP
 biological_processGO:0030886 negative regulation of myeloid dendritic cell activation IMP
 biological_processGO:0032088 negative regulation of NF-kappaB transcription factor activity IMP
 biological_processGO:0032687 negative regulation of interferon-alpha production IDA
 biological_processGO:0032689 negative regulation of interferon-gamma production IDA
 biological_processGO:0032703 negative regulation of interleukin-2 production IDA
 biological_processGO:0032712 negative regulation of interleukin-3 production IDA
 biological_processGO:0032715 negative regulation of interleukin-6 production IEA
 biological_processGO:0032720 negative regulation of tumor necrosis factor production IMP
 biological_processGO:0032722 positive regulation of chemokine production IEA
 biological_processGO:0032729 positive regulation of interferon-gamma production IEA
 biological_processGO:0032732 positive regulation of interleukin-1 production IEA
 biological_processGO:0032753 positive regulation of interleukin-4 production IMP
 biological_processGO:0032815 negative regulation of natural killer cell activation IEA
 biological_processGO:0034138 toll-like receptor 3 signaling pathway IEA
 biological_processGO:0034154 toll-like receptor 7 signaling pathway IEA
 biological_processGO:0034162 toll-like receptor 9 signaling pathway IEA
 biological_processGO:0042102 positive regulation of T cell proliferation IEA
 biological_processGO:0042130 negative regulation of T cell proliferation IEA
 biological_processGO:0043032 positive regulation of macrophage activation IEA
 biological_processGO:0045087 innate immune response IEA
 biological_processGO:0050830 defense response to Gram-positive bacterium IEA
 biological_processGO:0060135 maternal process involved in female pregnancy IDA
 biological_processGO:0070374 positive regulation of ERK1 and ERK2 cascade IEA
 biological_processGO:0071222 cellular response to lipopolysaccharide IEA
 biological_processGO:0071656 negative regulation of granulocyte colony-stimulating factor production IDA
 biological_processGO:1900425 negative regulation of defense response to bacterium IEA
 biological_processGO:1900426 positive regulation of defense response to bacterium IEA
 biological_processGO:1901224 positive regulation of NIK/NF-kappaB signaling IEA
 biological_processGO:1904469 positive regulation of tumor necrosis factor secretion IMP
 biological_processGO:2000521 negative regulation of immunological synapse formation IEA
 biological_processGO:2001189 negative regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell IDA
 cellular_componentGO:0001772 immunological synapse IEA
 cellular_componentGO:0005769 early endosome IEA
 cellular_componentGO:0009986 cell surface IDA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0016592 mediator complex IBA
 cellular_componentGO:0030054 cell junction IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
No match


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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