8660


Homo sapiens (NCBI)

Features
Gene ID: 8660
  
Biological name :
  
Synonyms : insulin receptor substrate 2 / IRS2
  
Possible biological names infered from orthology :
  
Species: Homo sapiens (NCBI)
  
Chr. number:
Strand:
Band:
Gene start:
Gene end:
  
Corresponding Affymetrix probe sets: 209184_s_at (Human Genome U133 Plus 2.0 Array)   209185_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: RefSeq - 38683860
RefSeq - NC_000013.11
RefSeq - NG_008154.1
RefSeq - NP_003740.2
RefSeq - NM_003749.2
  
See co-cited genes in PubMed
Warning: Please see the Ensembl gene model ENSG00000185950 to get all the annotations available for this gene.


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000165 MAPK cascade TAS
 biological_processGO:0002053 positive regulation of mesenchymal cell proliferation IEA
 biological_processGO:0002903 negative regulation of B cell apoptotic process ISS
 biological_processGO:0006006 glucose metabolic process TAS
 biological_processGO:0007165 signal transduction TAS
 biological_processGO:0007411 axon guidance TAS
 biological_processGO:0007420 brain development IEA
 biological_processGO:0008283 cell proliferation IEA
 biological_processGO:0008284 positive regulation of cell proliferation NAS
 biological_processGO:0008286 insulin receptor signaling pathway ISS
 biological_processGO:0009749 response to glucose ISS
 biological_processGO:0010748 negative regulation of plasma membrane long-chain fatty acid transport IMP
 biological_processGO:0010907 positive regulation of glucose metabolic process IMP
 biological_processGO:0019216 regulation of lipid metabolic process TAS
 biological_processGO:0030335 positive regulation of cell migration IEA
 biological_processGO:0030879 mammary gland development IEA
 biological_processGO:0030890 positive regulation of B cell proliferation ISS
 biological_processGO:0032000 positive regulation of fatty acid beta-oxidation IMP
 biological_processGO:0032024 positive regulation of insulin secretion ISS
 biological_processGO:0032869 cellular response to insulin stimulus IMP
 biological_processGO:0033673 negative regulation of kinase activity ISS
 biological_processGO:0036092 phosphatidylinositol-3-phosphate biosynthetic process IEA
 biological_processGO:0038111 interleukin-7-mediated signaling pathway TAS
 biological_processGO:0045725 positive regulation of glycogen biosynthetic process NAS
 biological_processGO:0046326 positive regulation of glucose import IMP
 biological_processGO:0046854 phosphatidylinositol phosphorylation IEA
 biological_processGO:0048015 phosphatidylinositol-mediated signaling TAS
 biological_processGO:0051897 positive regulation of protein kinase B signaling TAS
 biological_processGO:0055088 lipid homeostasis TAS
 biological_processGO:0071333 cellular response to glucose stimulus IEA
 cellular_componentGO:0005829 cytosol TAS
 cellular_componentGO:0005886 plasma membrane TAS
 cellular_componentGO:0032991 protein-containing complex IEA
 molecular_functionGO:0005088 Ras guanyl-nucleotide exchange factor activity TAS
 molecular_functionGO:0005158 insulin receptor binding IBA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0016303 1-phosphatidylinositol-3-kinase activity TAS
 molecular_functionGO:0019901 protein kinase binding IEA
 molecular_functionGO:0019903 protein phosphatase binding IEA
 molecular_functionGO:0019904 protein domain specific binding IEA
 molecular_functionGO:0043548 phosphatidylinositol 3-kinase binding IBA
 molecular_functionGO:0046934 phosphatidylinositol-4,5-bisphosphate 3-kinase activity TAS
 molecular_functionGO:0071889 14-3-3 protein binding IEA


Pathways (from Reactome)
Pathway description
No match


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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