8743


Homo sapiens (NCBI)

Features
Gene ID: 8743
  
Biological name :
  
Synonyms : APO2L|Apo-2L|CD253|TL2|TNLG6A|TRAIL / TNFSF10 / TNF superfamily member 10
  
Possible biological names infered from orthology :
  
Species: Homo sapiens (NCBI)
  
Chr. number:
Strand:
Band:
Gene start:
Gene end:
  
Corresponding Affymetrix probe sets: 202687_s_at (Human Genome U133 Plus 2.0 Array)   202688_at (Human Genome U133 Plus 2.0 Array)   214329_x_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: RefSeq - NP_001177871.1
RefSeq - NP_001177872.1
RefSeq - NP_003801.1
RefSeq - 300193032
RefSeq - 300193034
RefSeq - 4507593
RefSeq - NC_000003.12
RefSeq - NR_033994.1
RefSeq - NM_001190942.1
RefSeq - NM_001190943.1
RefSeq - NM_003810.3
  
See co-cited genes in PubMed
Warning: Please see the Ensembl gene model ENSG00000121858 to get all the annotations available for this gene.


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006915 apoptotic process IEA
 biological_processGO:0006919 activation of cysteine-type endopeptidase activity involved in apoptotic process TAS
 biological_processGO:0006955 immune response IEA
 biological_processGO:0007165 signal transduction TAS
 biological_processGO:0007166 cell surface receptor signaling pathway TAS
 biological_processGO:0007267 cell-cell signaling TAS
 biological_processGO:0008584 male gonad development IEA
 biological_processGO:0010469 regulation of signaling receptor activity IEA
 biological_processGO:0032868 response to insulin IEA
 biological_processGO:0043065 positive regulation of apoptotic process IDA
 biological_processGO:0043123 positive regulation of I-kappaB kinase/NF-kappaB signaling IEP
 biological_processGO:0043280 positive regulation of cysteine-type endopeptidase activity involved in apoptotic process IDA
 biological_processGO:0090200 positive regulation of release of cytochrome c from mitochondria IDA
 biological_processGO:1902041 regulation of extrinsic apoptotic signaling pathway via death domain receptors TAS
 biological_processGO:1902042 negative regulation of extrinsic apoptotic signaling pathway via death domain receptors TAS
 biological_processGO:2001238 positive regulation of extrinsic apoptotic signaling pathway IDA
 cellular_componentGO:0005576 extracellular region TAS
 cellular_componentGO:0005887 integral component of plasma membrane TAS
 cellular_componentGO:0070062 extracellular exosome HDA
 molecular_functionGO:0005102 signaling receptor binding TAS
 molecular_functionGO:0005125 cytokine activity IEA
 molecular_functionGO:0005164 tumor necrosis factor receptor binding IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0008270 zinc ion binding IDA
 molecular_functionGO:0042802 identical protein binding IDA
 molecular_functionGO:0045569 TRAIL binding IEA


Pathways (from Reactome)
Pathway description
No match


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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