8767


Homo sapiens (NCBI)

Features
Gene ID: 8767
  
Biological name :
  
Synonyms : CARD3|CARDIAK|CCK|GIG30|RICK|RIP2 / receptor interacting serine/threonine kinase 2 / RIPK2
  
Possible biological names infered from orthology :
  
Species: Homo sapiens (NCBI)
  
Chr. number:
Strand:
Band:
Gene start:
Gene end:
  
Corresponding Affymetrix probe sets: 209544_at (Human Genome U133 Plus 2.0 Array)   209545_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: RefSeq - 4506537
RefSeq - 530389383
RefSeq - 767953763
RefSeq - NC_000008.11
RefSeq - NG_033016.1
RefSeq - NP_003812.1
RefSeq - XP_005251149.1
RefSeq - XP_011515659.1
RefSeq - NM_003821.5
RefSeq - XM_011517357.2
RefSeq - XM_005251092.3
  
See co-cited genes in PubMed
Warning: Please see the Ensembl gene model ENSG00000104312 to get all the annotations available for this gene.


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000165 MAPK cascade IBA
 biological_processGO:0000187 activation of MAPK activity TAS
 biological_processGO:0001961 positive regulation of cytokine-mediated signaling pathway IEA
 biological_processGO:0002250 adaptive immune response ISS
 biological_processGO:0002819 regulation of adaptive immune response IBA
 biological_processGO:0006915 apoptotic process IEA
 biological_processGO:0006954 inflammatory response TAS
 biological_processGO:0007165 signal transduction TAS
 biological_processGO:0007249 I-kappaB kinase/NF-kappaB signaling ISS
 biological_processGO:0007254 JNK cascade TAS
 biological_processGO:0007257 activation of JUN kinase activity IBA
 biological_processGO:0010800 positive regulation of peptidyl-threonine phosphorylation IDA
 biological_processGO:0010942 positive regulation of cell death IDA
 biological_processGO:0018108 peptidyl-tyrosine phosphorylation IEA
 biological_processGO:0031398 positive regulation of protein ubiquitination NAS
 biological_processGO:0031663 lipopolysaccharide-mediated signaling pathway IEA
 biological_processGO:0032092 positive regulation of protein binding IMP
 biological_processGO:0032722 positive regulation of chemokine production IEA
 biological_processGO:0032727 positive regulation of interferon-alpha production NAS
 biological_processGO:0032728 positive regulation of interferon-beta production NAS
 biological_processGO:0032729 positive regulation of interferon-gamma production IEA
 biological_processGO:0032735 positive regulation of interleukin-12 production NAS
 biological_processGO:0032743 positive regulation of interleukin-2 production IEA
 biological_processGO:0032755 positive regulation of interleukin-6 production IEA
 biological_processGO:0032760 positive regulation of tumor necrosis factor production IEA
 biological_processGO:0033091 positive regulation of immature T cell proliferation IEA
 biological_processGO:0033138 positive regulation of peptidyl-serine phosphorylation IDA
 biological_processGO:0034134 toll-like receptor 2 signaling pathway IDA
 biological_processGO:0034142 toll-like receptor 4 signaling pathway IEA
 biological_processGO:0042098 T cell proliferation IEA
 biological_processGO:0043029 T cell homeostasis IBA
 biological_processGO:0043065 positive regulation of apoptotic process IEA
 biological_processGO:0043066 negative regulation of apoptotic process TAS
 biological_processGO:0043123 positive regulation of I-kappaB kinase/NF-kappaB signaling IDA
 biological_processGO:0043330 response to exogenous dsRNA IEA
 biological_processGO:0045087 innate immune response ISS
 biological_processGO:0045627 positive regulation of T-helper 1 cell differentiation IEA
 biological_processGO:0045944 positive regulation of transcription by RNA polymerase II NAS
 biological_processGO:0046330 positive regulation of JNK cascade IEA
 biological_processGO:0046641 positive regulation of alpha-beta T cell proliferation IEA
 biological_processGO:0050718 positive regulation of interleukin-1 beta secretion IDA
 biological_processGO:0050731 positive regulation of peptidyl-tyrosine phosphorylation IDA
 biological_processGO:0050830 defense response to Gram-positive bacterium IEA
 biological_processGO:0050852 T cell receptor signaling pathway TAS
 biological_processGO:0051092 positive regulation of NF-kappaB transcription factor activity TAS
 biological_processGO:0070266 necroptotic process IBA
 biological_processGO:0070374 positive regulation of ERK1 and ERK2 cascade IEA
 biological_processGO:0070423 nucleotide-binding oligomerization domain containing signaling pathway TAS
 biological_processGO:0070427 nucleotide-binding oligomerization domain containing 1 signaling pathway IEA
 biological_processGO:0070431 nucleotide-binding oligomerization domain containing 2 signaling pathway IDA
 biological_processGO:0070498 interleukin-1-mediated signaling pathway TAS
 biological_processGO:0070671 response to interleukin-12 IEA
 biological_processGO:0070673 response to interleukin-18 IEA
 biological_processGO:0071223 cellular response to lipoteichoic acid IEA
 biological_processGO:0071224 cellular response to peptidoglycan IEA
 biological_processGO:0071225 cellular response to muramyl dipeptide IDA
 biological_processGO:0097202 activation of cysteine-type endopeptidase activity IDA
 biological_processGO:1904417 positive regulation of xenophagy IEA
 cellular_componentGO:0005737 cytoplasm IDA
 cellular_componentGO:0005829 cytosol TAS
 cellular_componentGO:0005856 cytoskeleton IDA
 cellular_componentGO:0031982 vesicle IDA
 cellular_componentGO:0032991 protein-containing complex IMP
 molecular_functionGO:0004674 protein serine/threonine kinase activity TAS
 molecular_functionGO:0004706 JUN kinase kinase kinase activity IBA
 molecular_functionGO:0004715 non-membrane spanning protein tyrosine kinase activity IEA
 molecular_functionGO:0005102 signaling receptor binding IPI
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0030274 LIM domain binding IPI
 molecular_functionGO:0042802 identical protein binding IPI
 molecular_functionGO:0042803 protein homodimerization activity IDA
 molecular_functionGO:0050700 CARD domain binding IPI
 molecular_functionGO:0089720 caspase binding IPI


Pathways (from Reactome)
Pathway description
No match


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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