8837


Homo sapiens (NCBI)

Features
Gene ID: 8837
  
Biological name :
  
Synonyms : CASH|CASP8AP1|CLARP|Casper|FLAME|FLAME-1|FLAME1|FLIP|I-FLICE|MRIT|c-FLIP|c-FLIPL|c-FLIPR|c-FLIPS / CASP8 and FADD like apoptosis regulator / CFLAR
  
Possible biological names infered from orthology :
  
Species: Homo sapiens (NCBI)
  
Chr. number:
Strand:
Band:
Gene start:
Gene end:
  
Corresponding Affymetrix probe sets: 208485_x_at (Human Genome U133 Plus 2.0 Array)   209508_x_at (Human Genome U133 Plus 2.0 Array)   209939_x_at (Human Genome U133 Plus 2.0 Array)   210563_x_at (Human Genome U133 Plus 2.0 Array)   210564_x_at (Human Genome U133 Plus 2.0 Array)   211316_x_at (Human Genome U133 Plus 2.0 Array)   211317_s_at (Human Genome U133 Plus 2.0 Array)   211862_x_at (Human Genome U133 Plus 2.0 Array)   214486_x_at (Human Genome U133 Plus 2.0 Array)   214618_at (Human Genome U133 Plus 2.0 Array)   217654_at (Human Genome U133 Plus 2.0 Array)   235427_at (Human Genome U133 Plus 2.0 Array)   237367_x_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: RefSeq - NC_000002.12
RefSeq - 1034617409
RefSeq - 1034617411
RefSeq - 1034617416
RefSeq - 1034617422
RefSeq - 1191704852
RefSeq - 1191704868
RefSeq - 1191704875
RefSeq - 1191704882
RefSeq - 1191704884
RefSeq - 187608571
RefSeq - 187608577
RefSeq - 187608585
RefSeq - 321267564
RefSeq - 321267567
RefSeq - 321267569
RefSeq - 321267571
RefSeq - 321267573
RefSeq - 808688347
RefSeq - 808688349
RefSeq - 1034617407
RefSeq - NG_029005.1
RefSeq - NP_001120655.1
RefSeq - NP_001120656.1
RefSeq - NP_001189444.1
RefSeq - NP_001189445.1
RefSeq - NP_001189446.1
RefSeq - NP_001189447.1
RefSeq - NP_001189448.1
RefSeq - NP_001294971.1
RefSeq - NP_001294972.1
RefSeq - NP_001338519.1
RefSeq - NP_001338520.1
RefSeq - NP_001338521.1
RefSeq - NP_001338522.1
RefSeq - NP_001338523.1
RefSeq - NP_003870.4
RefSeq - XP_016860678.1
RefSeq - XP_016860679.1
RefSeq - XP_016860680.1
RefSeq - XP_016860682.1
RefSeq - XP_016860684.1
RefSeq - XM_017005190.2
RefSeq - XM_017005191.2
RefSeq - XM_017005193.2
RefSeq - XM_017005195.2
RefSeq - XR_001739016.2
RefSeq - XR_001739017.2
RefSeq - XR_001739018.1
RefSeq - XR_002959354.1
RefSeq - XR_002959355.1
RefSeq - XR_001739013.2
RefSeq - NR_147241.1
RefSeq - NR_147242.1
RefSeq - NR_147243.1
RefSeq - NR_147244.1
RefSeq - NR_147245.1
RefSeq - NR_147246.1
RefSeq - NR_147247.1
RefSeq - NR_147248.1
RefSeq - NR_147249.1
RefSeq - NR_147250.1
RefSeq - NM_001127183.3
RefSeq - NM_001127184.3
RefSeq - NM_001202515.1
RefSeq - NM_001202516.2
RefSeq - NM_001202517.2
RefSeq - NM_001202518.1
RefSeq - NM_001202519.2
RefSeq - NM_001308042.2
RefSeq - NM_001308043.1
RefSeq - NM_001351590.1
RefSeq - NM_001351591.1
RefSeq - NM_001351592.1
RefSeq - NM_001351593.1
RefSeq - NM_001351594.1
RefSeq - NM_003879.6
RefSeq - NR_147251.1
RefSeq - NR_147252.1
RefSeq - NR_147253.1
RefSeq - NR_147255.1
RefSeq - XM_017005189.2
  
See co-cited genes in PubMed
Warning: Please see the Ensembl gene model ENSG00000003402 to get all the annotations available for this gene.


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006508 proteolysis IEA
 biological_processGO:0006915 apoptotic process IMP
 biological_processGO:0007519 skeletal muscle tissue development ISS
 biological_processGO:0010667 negative regulation of cardiac muscle cell apoptotic process IEA
 biological_processGO:0010952 positive regulation of peptidase activity IEA
 biological_processGO:0010976 positive regulation of neuron projection development IEA
 biological_processGO:0014732 skeletal muscle atrophy ISS
 biological_processGO:0014842 regulation of skeletal muscle satellite cell proliferation ISS
 biological_processGO:0014866 skeletal myofibril assembly ISS
 biological_processGO:0016032 viral process IEA
 biological_processGO:0032869 cellular response to insulin stimulus IEA
 biological_processGO:0033574 response to testosterone IEA
 biological_processGO:0043066 negative regulation of apoptotic process TAS
 biological_processGO:0043123 positive regulation of I-kappaB kinase/NF-kappaB signaling IEP
 biological_processGO:0043154 negative regulation of cysteine-type endopeptidase activity involved in apoptotic process IEA
 biological_processGO:0043403 skeletal muscle tissue regeneration ISS
 biological_processGO:0051092 positive regulation of NF-kappaB transcription factor activity ISS
 biological_processGO:0060544 regulation of necroptotic process IDA
 biological_processGO:0060546 negative regulation of necroptotic process IEA
 biological_processGO:0070374 positive regulation of ERK1 and ERK2 cascade IEA
 biological_processGO:0071364 cellular response to epidermal growth factor stimulus IEA
 biological_processGO:0071392 cellular response to estradiol stimulus IEA
 biological_processGO:0071456 cellular response to hypoxia IEA
 biological_processGO:0071549 cellular response to dexamethasone stimulus IEA
 biological_processGO:0071732 cellular response to nitric oxide IEA
 biological_processGO:0072126 positive regulation of glomerular mesangial cell proliferation IEA
 biological_processGO:1901740 negative regulation of myoblast fusion ISS
 biological_processGO:1902041 regulation of extrinsic apoptotic signaling pathway via death domain receptors TAS
 biological_processGO:1902042 negative regulation of extrinsic apoptotic signaling pathway via death domain receptors TAS
 biological_processGO:1903055 positive regulation of extracellular matrix organization IEA
 biological_processGO:1903427 negative regulation of reactive oxygen species biosynthetic process IEA
 biological_processGO:1903845 negative regulation of cellular response to transforming growth factor beta stimulus IEA
 biological_processGO:1903944 negative regulation of hepatocyte apoptotic process IEA
 biological_processGO:2000347 positive regulation of hepatocyte proliferation IEA
 biological_processGO:2001237 negative regulation of extrinsic apoptotic signaling pathway IMP
 cellular_componentGO:0005737 cytoplasm IDA
 cellular_componentGO:0005829 cytosol TAS
 cellular_componentGO:0031264 death-inducing signaling complex IDA
 cellular_componentGO:0031265 CD95 death-inducing signaling complex IEA
 cellular_componentGO:0045121 membrane raft IEA
 cellular_componentGO:0097342 ripoptosome IDA
 molecular_functionGO:0002020 protease binding IPI
 molecular_functionGO:0005123 death receptor binding IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0008047 enzyme activator activity IDA
 molecular_functionGO:0016504 peptidase activator activity IEA
 molecular_functionGO:0044877 protein-containing complex binding IEA
 molecular_functionGO:0046982 protein heterodimerization activity IEA
 molecular_functionGO:0097153 cysteine-type endopeptidase activity involved in apoptotic process IBA


Pathways (from Reactome)
Pathway description
No match


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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