8877


Homo sapiens (NCBI)

Features
Gene ID: 8877
  
Biological name :
  
Synonyms : sphingosine kinase 1 / SPHK / SPHK1
  
Possible biological names infered from orthology :
  
Species: Homo sapiens (NCBI)
  
Chr. number:
Strand:
Band:
Gene start:
Gene end:
  
Corresponding Affymetrix probe sets: 219257_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: RefSeq - 1243057649
RefSeq - 21361088
RefSeq - 217272880
RefSeq - 217272883
RefSeq - 217272885
RefSeq - NC_000017.11
RefSeq - NP_001136073.1
RefSeq - NP_001136074.1
RefSeq - NP_001342068.1
RefSeq - NP_068807.2
RefSeq - NP_892010.2
RefSeq - NM_001142601.1
RefSeq - NM_001142602.1
RefSeq - NM_001355139.1
RefSeq - NM_021972.3
RefSeq - NM_182965.2
  
See co-cited genes in PubMed
Warning: Please see the Ensembl gene model ENSG00000176170 to get all the annotations available for this gene.


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001568 blood vessel development IEA
 biological_processGO:0003376 sphingosine-1-phosphate signaling pathway IEA
 biological_processGO:0006457 protein folding TAS
 biological_processGO:0006670 sphingosine metabolic process IDA
 biological_processGO:0006954 inflammatory response IEA
 biological_processGO:0007165 signal transduction TAS
 biological_processGO:0007420 brain development IEA
 biological_processGO:0010800 positive regulation of peptidyl-threonine phosphorylation IMP
 biological_processGO:0010803 regulation of tumor necrosis factor-mediated signaling pathway IDA
 biological_processGO:0019722 calcium-mediated signaling IDA
 biological_processGO:0030148 sphingolipid biosynthetic process TAS
 biological_processGO:0030307 positive regulation of cell growth IDA
 biological_processGO:0030335 positive regulation of cell migration IDA
 biological_processGO:0031398 positive regulation of protein ubiquitination IDA
 biological_processGO:0032651 regulation of interleukin-1 beta production IEA
 biological_processGO:0035556 intracellular signal transduction TAS
 biological_processGO:0043066 negative regulation of apoptotic process TAS
 biological_processGO:0045766 positive regulation of angiogenesis IDA
 biological_processGO:0045931 positive regulation of mitotic cell cycle IDA
 biological_processGO:0045987 positive regulation of smooth muscle contraction IDA
 biological_processGO:0046512 sphingosine biosynthetic process IMP
 biological_processGO:0046521 sphingoid catabolic process NAS
 biological_processGO:0046834 lipid phosphorylation IEA
 biological_processGO:0048146 positive regulation of fibroblast proliferation IDA
 biological_processGO:0051092 positive regulation of NF-kappaB transcription factor activity IMP
 biological_processGO:1901224 positive regulation of NIK/NF-kappaB signaling IMP
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005737 cytoplasm IDA
 cellular_componentGO:0005829 cytosol TAS
 cellular_componentGO:0005886 plasma membrane IDA
 molecular_functionGO:0000287 magnesium ion binding ISS
 molecular_functionGO:0003677 DNA binding IDA
 molecular_functionGO:0003951 NAD+ kinase activity IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0005516 calmodulin binding IDA
 molecular_functionGO:0005524 ATP binding IDA
 molecular_functionGO:0008481 sphinganine kinase activity TAS
 molecular_functionGO:0017050 D-erythro-sphingosine kinase activity TAS
 molecular_functionGO:0038036 sphingosine-1-phosphate receptor activity IMP
 molecular_functionGO:0051721 protein phosphatase 2A binding IPI


Pathways (from Reactome)
Pathway description
No match


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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