8945


Homo sapiens (NCBI)

Features
Gene ID: 8945
  
Biological name :
  
Synonyms : beta-transducin repeat containing E3 ubiquitin protein ligase / BETA-TRCP|FBW1A|FBXW1|FBXW1A|FWD1|bTrCP|bTrCP1|betaTrCP / BTRC
  
Possible biological names infered from orthology :
  
Species: Homo sapiens (NCBI)
  
Chr. number:
Strand:
Band:
Gene start:
Gene end:
  
Corresponding Affymetrix probe sets: 1563620_at (Human Genome U133 Plus 2.0 Array)   204901_at (Human Genome U133 Plus 2.0 Array)   216091_s_at (Human Genome U133 Plus 2.0 Array)   222374_at (Human Genome U133 Plus 2.0 Array)   224471_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: RefSeq - 1034570179
RefSeq - 1034570181
RefSeq - 1034570183
RefSeq - 1034570185
RefSeq - 1034570187
RefSeq - 1370458086
RefSeq - 1370458088
RefSeq - 16117783
RefSeq - 379030596
RefSeq - 4502477
RefSeq - 578819981
RefSeq - 767964191
RefSeq - NC_000010.11
RefSeq - NG_009234.1
RefSeq - NP_001243785.1
RefSeq - NP_003930.1
RefSeq - NP_378663.1
RefSeq - XP_006718117.1
RefSeq - XP_011538622.1
RefSeq - XP_016872359.1
RefSeq - XP_016872360.1
RefSeq - XP_016872361.1
RefSeq - XP_016872362.1
RefSeq - XP_016872363.1
RefSeq - XP_024304014.1
RefSeq - XP_024304015.1
RefSeq - XM_017016874.1
RefSeq - NM_001256856.1
RefSeq - NM_003939.4
RefSeq - NM_033637.3
RefSeq - XM_024448246.1
RefSeq - XM_024448247.1
RefSeq - XR_001747256.1
RefSeq - XM_006718054.2
RefSeq - XM_011540320.2
RefSeq - XM_017016870.1
RefSeq - XM_017016871.1
RefSeq - XM_017016872.1
RefSeq - XM_017016873.2
  
See co-cited genes in PubMed
Warning: Please see the Ensembl gene model ENSG00000166167 to get all the annotations available for this gene.


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000086 G2/M transition of mitotic cell cycle TAS
 biological_processGO:0000209 protein polyubiquitination TAS
 biological_processGO:0000462 maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) IBA
 biological_processGO:0006470 protein dephosphorylation ISS
 biological_processGO:0006511 ubiquitin-dependent protein catabolic process IDA
 biological_processGO:0007165 signal transduction TAS
 biological_processGO:0016032 viral process IEA
 biological_processGO:0016055 Wnt signaling pathway TAS
 biological_processGO:0016567 protein ubiquitination IDA
 biological_processGO:0031146 SCF-dependent proteasomal ubiquitin-dependent protein catabolic process ISS
 biological_processGO:0031648 protein destabilization IMP
 biological_processGO:0033598 mammary gland epithelial cell proliferation IEA
 biological_processGO:0038061 NIK/NF-kappaB signaling TAS
 biological_processGO:0042752 regulation of circadian rhythm IDA
 biological_processGO:0042753 positive regulation of circadian rhythm ISS
 biological_processGO:0043122 regulation of I-kappaB kinase/NF-kappaB signaling IEA
 biological_processGO:0043161 proteasome-mediated ubiquitin-dependent protein catabolic process IDA
 biological_processGO:0043433 negative regulation of DNA-binding transcription factor activity TAS
 biological_processGO:0043687 post-translational protein modification TAS
 biological_processGO:0045862 positive regulation of proteolysis IMP
 biological_processGO:0045879 negative regulation of smoothened signaling pathway TAS
 biological_processGO:0045892 negative regulation of transcription, DNA-templated IMP
 biological_processGO:0045893 positive regulation of transcription, DNA-templated ISS
 biological_processGO:0048511 rhythmic process IEA
 biological_processGO:0051403 stress-activated MAPK cascade TAS
 biological_processGO:0051726 regulation of cell cycle IEA
 biological_processGO:0060444 branching involved in mammary gland duct morphogenesis IEA
 biological_processGO:0060828 regulation of canonical Wnt signaling pathway IC
 biological_processGO:0061136 regulation of proteasomal protein catabolic process IEA
 biological_processGO:0070498 interleukin-1-mediated signaling pathway TAS
 biological_processGO:0071407 cellular response to organic cyclic compound IEA
 cellular_componentGO:0005654 nucleoplasm TAS
 cellular_componentGO:0005829 cytosol TAS
 cellular_componentGO:0019005 SCF ubiquitin ligase complex IDA
 cellular_componentGO:0032040 small-subunit processome IBA
 cellular_componentGO:0034388 Pwp2p-containing subcomplex of 90S preribosome IBA
 molecular_functionGO:0004842 ubiquitin-protein transferase activity TAS
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0008013 beta-catenin binding IDA
 molecular_functionGO:0016874 ligase activity IEA
 molecular_functionGO:0030515 snoRNA binding IBA
 molecular_functionGO:0045309 protein phosphorylated amino acid binding IEA
 molecular_functionGO:0046983 protein dimerization activity IEA
 molecular_functionGO:0061630 ubiquitin protein ligase activity IDA


Pathways (from Reactome)
Pathway description
No match


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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