90865


Homo sapiens (NCBI)
regulationproductionresponseinterleukin-immunesignalingproteinsecretioncytokinemicroglialcellactivationtypetranscriptionactivitypathwayimmunoglobulinextracellularinvolvedleukocytemigrationt-helperdna-templatedreceptordeubiquitinationproteasomalubiquitin-dependentcatabolicprocessinterferon-gamma

Features
Gene ID: 90865
  
Biological name :
  
Synonyms : C9orf26|DVS27|IL1F11|NF-HEV|NFEHEV / IL33 / interleukin 33
  
Possible biological names infered from orthology :
  
Species: Homo sapiens (NCBI)
  
Chr. number:
Strand:
Band:
Gene start:
Gene end:
  
Corresponding Affymetrix probe sets: 209821_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: RefSeq - 1034671840
RefSeq - 1219862488
RefSeq - 15559209
RefSeq - 313851030
RefSeq - 314122337
RefSeq - 930588927
RefSeq - 930588929
RefSeq - 930588931
RefSeq - 930588933
RefSeq - 930588935
RefSeq - NC_000009.12
RefSeq - NG_047209.1
RefSeq - NP_001186569.1
RefSeq - NP_001186570.1
RefSeq - NP_001300973.1
RefSeq - NP_001300974.1
RefSeq - NP_001300975.1
RefSeq - NP_001300976.1
RefSeq - NP_001300977.1
RefSeq - NP_001340731.1
RefSeq - NP_254274.1
RefSeq - XP_016870774.1
RefSeq - NM_001199640.1
RefSeq - NM_001199641.1
RefSeq - NM_001314044.1
RefSeq - NM_001314045.1
RefSeq - NM_001314046.1
RefSeq - NM_001314047.1
RefSeq - NM_001314048.1
RefSeq - NM_001353802.1
RefSeq - NM_033439.3
RefSeq - XM_017015285.1
  
See co-cited genes in PubMed
Warning: Please see the Ensembl gene model ENSG00000137033 to get all the annotations available for this gene.


Gene Ontology (GO)
cytokine productionimmune responsecell activationimmune effector processlocalization of cellmovement of cell or subcellular componentnitrogen compound metabolic processbiosynthetic processcellular metabolic processprimary metabolic processorganic substance metabolic processcell communicationregulation of molecular functioncellular response to stimuluscatabolic processresponse to chemicalresponse to stressresponse to external stimulusproduction of molecular mediator of immune responsemacromolecule localizationestablishment of localizationresponse to biotic stimulusanatomical structure developmentcellular developmental processleukocyte proliferationcell deathcytokine productionimmune responsecell activationimmune effector processlocalization of cellmovement of cell or subcellular componentnitrogen compound metabolic processbiosynthetic processcellular metabolic processprimary metabolic processorganic substance metabolic processcell communicationregulation of molecular functioncellular response to stimuluscatabolic processresponse to chemicalresponse to stressresponse to external stimulusproduction of molecular mediator of immune responsemacromolecule localizationestablishment of localizationresponse to biotic stimulusanatomical structure developmentcellular developmental processleukocyte proliferationcell deathcytokine productionimmune responsecell activationimmune effector processlocalization of cellmovement of cell or subcellular componentnitrogen compound metabolic processbiosynthetic processcellular metabolic processprimary metabolic processorganic substance metabolic processcell communicationregulation of molecular functioncellular response to stimuluscatabolic processresponse to chemicalresponse to stressresponse to external stimulusproduction of molecular mediator of immune responsemacromolecule localizationestablishment of localizationresponse to biotic stimulusanatomical structure developmentcellular developmental processleukocyte proliferationcell deathcytokine productionimmune responsecell activationimmune effector processlocalization of cellmovement of cell or subcellular componentnitrogen compound metabolic processbiosynthetic processcellular metabolic processprimary metabolic processorganic substance metabolic processcell communicationregulation of molecular functioncellular response to stimuluscatabolic processresponse to chemicalresponse to stressresponse to external stimulusproduction of molecular mediator of immune responsemacromolecule localizationestablishment of localizationresponse to biotic stimulusanatomical structure developmentcellular developmental processleukocyte proliferationcell deathcytokine productionimmune responsecell activationimmune effector processlocalization of cellmovement of cell or subcellular componentnitrogen compound metabolic processbiosynthetic processcellular metabolic processprimary metabolic processorganic substance metabolic processcell communicationregulation of molecular functioncellular response to stimuluscatabolic processresponse to chemicalresponse to stressresponse to external stimulusproduction of molecular mediator of immune responsemacromolecule localizationestablishment of localizationresponse to biotic stimulusanatomical structure developmentcellular developmental processleukocyte proliferationcell deathcytokine productionimmune responsecell activationimmune effector processlocalization of cellmovement of cell or subcellular componentnitrogen compound metabolic processbiosynthetic processcellular metabolic processprimary metabolic processorganic substance metabolic processcell communicationregulation of molecular functioncellular response to stimuluscatabolic processresponse to chemicalresponse to stressresponse to external stimulusproduction of molecular mediator of immune responsemacromolecule localizationestablishment of localizationresponse to biotic stimulusanatomical structure developmentcellular developmental processleukocyte proliferationcell deathcytokine productionimmune responsecell activationimmune effector processlocalization of cellmovement of cell or subcellular componentnitrogen compound metabolic processbiosynthetic processcellular metabolic processprimary metabolic processorganic substance metabolic processcell communicationregulation of molecular functioncellular response to stimuluscatabolic processresponse to chemicalresponse to stressresponse to external stimulusproduction of molecular mediator of immune responsemacromolecule localizationestablishment of localizationresponse to biotic stimulusanatomical structure developmentcellular developmental processleukocyte proliferationcell deathcytokine productionimmune responsecell activationimmune effector processlocalization of cellmovement of cell or subcellular componentnitrogen compound metabolic processbiosynthetic processcellular metabolic processprimary metabolic processorganic substance metabolic processcell communicationregulation of molecular functioncellular response to stimuluscatabolic processresponse to chemicalresponse to stressresponse to external stimulusproduction of molecular mediator of immune responsemacromolecule localizationestablishment of localizationresponse to biotic stimulusanatomical structure developmentcellular developmental processleukocyte proliferationcell deathcytokine productionimmune responsecell activationimmune effector processlocalization of cellmovement of cell or subcellular componentnitrogen compound metabolic processbiosynthetic processcellular metabolic processprimary metabolic processorganic substance metabolic processcell communicationregulation of molecular functioncellular response to stimuluscatabolic processresponse to chemicalresponse to stressresponse to external stimulusproduction of molecular mediator of immune responsemacromolecule localizationestablishment of localizationresponse to biotic stimulusanatomical structure developmentcellular developmental processleukocyte proliferationcell deathcytokine productionimmune responsecell activationimmune effector processlocalization of cellmovement of cell or subcellular componentnitrogen compound metabolic processbiosynthetic processcellular metabolic processprimary metabolic processorganic substance metabolic processcell communicationregulation of molecular functioncellular response to stimuluscatabolic processresponse to chemicalresponse to stressresponse to external stimulusproduction of molecular mediator of immune responsemacromolecule localizationestablishment of localizationresponse to biotic stimulusanatomical structure developmentcellular developmental processleukocyte proliferationcell deathcytokcytokine productionimmunimmune responsecell cell activationimmunimmune effector processlocallocalization of cellmovemmovement of cell or subcellular componentnitronitrogen compound metabolic processbiosybiosynthetic processcellucellular metabolic processprimaprimary metabolic processorganorganic substance metabolic processcell cell communicationregulregulation of molecular functioncellucellular response to stimuluscatabcatabolic processresporesponse to chemicalresporesponse to stressresporesponse to external stimulusproduproduction of molecular mediator of immune responsemacromacromolecule localizationestabestablishment of localizationresporesponse to biotic stimulusanatoanatomical structure developmentcellucellular developmental processleukoleukocyte proliferationcell cell death
protein bindingreceptor regulator activityprotein bindingreceptor regulator activityprotein bindingreceptor regulator activityprotein bindingreceptor regulator activityprotein bindingreceptor regulator activityprotein bindingreceptor regulator activityprotein bindingreceptor regulator activityprotein bindingreceptor regulator activityprotein bindingreceptor regulator activityprotein bindingreceptor regulator activityprotein bindingprotein bindingreceptor regulator activityreceptor regulator activity
extracellular regioncellorganellemembrane-enclosed lumenextracellular regioncellorganellemembrane-enclosed lumenextracellular regioncellorganellemembrane-enclosed lumenextracellular regioncellorganellemembrane-enclosed lumenextracellular regioncellorganellemembrane-enclosed lumenextracellular regioncellorganellemembrane-enclosed lumenextracellular regioncellorganellemembrane-enclosed lumenextracellular regioncellorganellemembrane-enclosed lumenextracellular regioncellorganellemembrane-enclosed lumenextracellular regioncellorganellemembrane-enclosed lumenextracellular regionextracellular regioncellcellorganelleorganellemembrane-enclosed lumenmembrane-enclosed lumen
TypeGO IDTermEv.Code
 biological_processGO:0001819 positive regulation of cytokine production IBA
 biological_processGO:0002282 microglial cell activation involved in immune response IEA
 biological_processGO:0002686 negative regulation of leukocyte migration IEA
 biological_processGO:0002826 negative regulation of T-helper 1 type immune response IEA
 biological_processGO:0002830 positive regulation of type 2 immune response IEA
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0010469 regulation of signaling receptor activity IEA
 biological_processGO:0016579 protein deubiquitination TAS
 biological_processGO:0032436 positive regulation of proteasomal ubiquitin-dependent protein catabolic process IEA
 biological_processGO:0032689 negative regulation of interferon-gamma production IEA
 biological_processGO:0032736 positive regulation of interleukin-13 production IEA
 biological_processGO:0032753 positive regulation of interleukin-4 production IEA
 biological_processGO:0032754 positive regulation of interleukin-5 production IEA
 biological_processGO:0032755 positive regulation of interleukin-6 production IEA
 biological_processGO:0038172 interleukin-33-mediated signaling pathway TAS
 biological_processGO:0043032 positive regulation of macrophage activation IDA
 biological_processGO:0045944 positive regulation of transcription by RNA polymerase II ISS
 biological_processGO:0050729 positive regulation of inflammatory response ISS
 biological_processGO:0051024 positive regulation of immunoglobulin secretion IEA
 biological_processGO:0051025 negative regulation of immunoglobulin secretion IEA
 biological_processGO:0051607 defense response to virus IEA
 biological_processGO:0061518 microglial cell proliferation IEA
 biological_processGO:0090197 positive regulation of chemokine secretion IDA
 biological_processGO:0097191 extrinsic apoptotic signaling pathway IEA
 cellular_componentGO:0005576 extracellular region TAS
 cellular_componentGO:0005615 extracellular space IEA
 cellular_componentGO:0005654 nucleoplasm TAS
 cellular_componentGO:0005694 chromosome IEA
 cellular_componentGO:0030133 transport vesicle IEA
 molecular_functionGO:0005125 cytokine activity IDA
 molecular_functionGO:0005515 protein binding IPI


Pathways (from Reactome)
Pathway description
No match


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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