9181


Homo sapiens (NCBI)

Features
Gene ID: 9181
  
Biological name :
  
Synonyms : ARHGEF2 / GEF|GEF-H1|GEFH1|LFP40|NEDMHM|P40 / Rho/Rac guanine nucleotide exchange factor 2
  
Possible biological names infered from orthology :
  
Species: Homo sapiens (NCBI)
  
Chr. number:
Strand:
Band:
Gene start:
Gene end:
  
Corresponding Affymetrix probe sets: 1554783_s_at (Human Genome U133 Plus 2.0 Array)   207629_s_at (Human Genome U133 Plus 2.0 Array)   209435_s_at (Human Genome U133 Plus 2.0 Array)   235595_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: RefSeq - 578801702
RefSeq - 1034563270
RefSeq - 1034563272
RefSeq - 1034563278
RefSeq - 1034563288
RefSeq - 1034563293
RefSeq - 1174098414
RefSeq - 1174098421
RefSeq - 1174098486
RefSeq - 1370455205
RefSeq - 1370455212
RefSeq - 15011974
RefSeq - 253735775
RefSeq - 253735778
RefSeq - 530365588
RefSeq - 530365590
RefSeq - 530365592
RefSeq - 530365594
RefSeq - 530365596
RefSeq - 530365602
RefSeq - 1034563268
RefSeq - 578801705
RefSeq - 578801707
RefSeq - 578801709
RefSeq - 578801711
RefSeq - 767910855
RefSeq - 767910871
RefSeq - NC_000001.11
RefSeq - NP_001155855.1
RefSeq - NP_001155856.1
RefSeq - NP_001337039.1
RefSeq - NP_001337040.1
RefSeq - NP_001337041.1
RefSeq - NP_004714.2
RefSeq - XP_005245644.1
RefSeq - XP_005245645.1
RefSeq - XP_005245646.1
RefSeq - XP_005245647.1
RefSeq - XP_005245648.1
RefSeq - XP_005245651.1
RefSeq - XP_006711685.1
RefSeq - XP_006711686.1
RefSeq - XP_006711687.1
RefSeq - XP_006711688.1
RefSeq - XP_006711689.1
RefSeq - XP_011508438.2
RefSeq - XP_011508439.2
RefSeq - XP_011508441.1
RefSeq - XP_011508445.1
RefSeq - XP_016858283.1
RefSeq - XP_016858284.1
RefSeq - XP_016858286.1
RefSeq - XP_016858287.1
RefSeq - XP_024306583.1
RefSeq - XP_024306591.1
RefSeq - NM_001162383.1
RefSeq - NM_001162384.1
RefSeq - NM_001350110.1
RefSeq - NM_001350111.1
RefSeq - NM_001350112.1
RefSeq - NM_004723.3
RefSeq - XM_017002794.2
RefSeq - XM_017002795.2
RefSeq - XM_017002797.2
RefSeq - XM_017002798.2
RefSeq - XM_024450815.1
RefSeq - XM_024450823.1
RefSeq - XM_005245587.3
RefSeq - XM_005245588.3
RefSeq - XM_005245589.5
RefSeq - XM_005245590.4
RefSeq - XM_005245591.4
RefSeq - XM_005245594.3
RefSeq - XM_006711622.4
RefSeq - XM_006711623.4
RefSeq - XM_006711624.4
RefSeq - XM_006711625.4
RefSeq - XM_006711626.3
RefSeq - XM_011510136.3
RefSeq - XM_011510137.3
RefSeq - XM_011510139.3
RefSeq - XM_011510143.3
  
See co-cited genes in PubMed
Warning: Please see the Ensembl gene model ENSG00000116584 to get all the annotations available for this gene.


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000132 establishment of mitotic spindle orientation IEA
 biological_processGO:0000902 cell morphogenesis IMP
 biological_processGO:0006886 intracellular protein transport NAS
 biological_processGO:0007015 actin filament organization IMP
 biological_processGO:0007026 negative regulation of microtubule depolymerization IMP
 biological_processGO:0007186 G-protein coupled receptor signaling pathway TAS
 biological_processGO:0032755 positive regulation of interleukin-6 production IDA
 biological_processGO:0032760 positive regulation of tumor necrosis factor production IDA
 biological_processGO:0035023 regulation of Rho protein signal transduction NAS
 biological_processGO:0035556 intracellular signal transduction IEA
 biological_processGO:0042127 regulation of cell proliferation TAS
 biological_processGO:0043065 positive regulation of apoptotic process TAS
 biological_processGO:0045087 innate immune response IEA
 biological_processGO:0045666 positive regulation of neuron differentiation IDA
 biological_processGO:0045944 positive regulation of transcription by RNA polymerase II IDA
 biological_processGO:0050731 positive regulation of peptidyl-tyrosine phosphorylation IDA
 biological_processGO:0050768 negative regulation of neurogenesis IEA
 biological_processGO:0051056 regulation of small GTPase mediated signal transduction TAS
 biological_processGO:0051092 positive regulation of NF-kappaB transcription factor activity IDA
 biological_processGO:0055059 asymmetric neuroblast division IDA
 biological_processGO:0060546 negative regulation of necroptotic process ISS
 biological_processGO:0071225 cellular response to muramyl dipeptide IDA
 biological_processGO:0071356 cellular response to tumor necrosis factor ISS
 biological_processGO:0071474 cellular hyperosmotic response ISS
 biological_processGO:0071802 negative regulation of podosome assembly IEA
 biological_processGO:1902042 negative regulation of extrinsic apoptotic signaling pathway via death domain receptors ISS
 biological_processGO:1902219 negative regulation of intrinsic apoptotic signaling pathway in response to osmotic stress ISS
 biological_processGO:2001224 positive regulation of neuron migration ISS
 cellular_componentGO:0002102 podosome IEA
 cellular_componentGO:0005737 cytoplasm IDA
 cellular_componentGO:0005794 Golgi apparatus IEA
 cellular_componentGO:0005819 spindle IEA
 cellular_componentGO:0005829 cytosol TAS
 cellular_componentGO:0005856 cytoskeleton IDA
 cellular_componentGO:0005874 microtubule IDA
 cellular_componentGO:0005923 bicellular tight junction IEA
 cellular_componentGO:0005925 focal adhesion HDA
 cellular_componentGO:0014069 postsynaptic density IEA
 cellular_componentGO:0031410 cytoplasmic vesicle IEA
 cellular_componentGO:0031982 vesicle IDA
 cellular_componentGO:0032587 ruffle membrane IDA
 cellular_componentGO:0032991 protein-containing complex IDA
 cellular_componentGO:0043025 neuronal cell body IEA
 cellular_componentGO:0043198 dendritic shaft IEA
 molecular_functionGO:0005085 guanyl-nucleotide exchange factor activity TAS
 molecular_functionGO:0005089 Rho guanyl-nucleotide exchange factor activity TAS
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0008017 microtubule binding IDA
 molecular_functionGO:0008134 transcription factor binding ISS
 molecular_functionGO:0008270 zinc ion binding NAS
 molecular_functionGO:0017048 Rho GTPase binding IDA
 molecular_functionGO:0030676 Rac guanyl-nucleotide exchange factor activity IDA
 molecular_functionGO:0048365 Rac GTPase binding IDA


Pathways (from Reactome)
Pathway description
No match


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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