9475


Homo sapiens (NCBI)

Features
Gene ID: 9475
  
Biological name :
  
Synonyms : Rho associated coiled-coil containing protein kinase 2 / ROCK2 / ROCK-II
  
Possible biological names infered from orthology :
  
Species: Homo sapiens (NCBI)
  
Chr. number:
Strand:
Band:
Gene start:
Gene end:
  
Corresponding Affymetrix probe sets: 202762_at (Human Genome U133 Plus 2.0 Array)   211504_x_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: RefSeq - XP_016860868.1
RefSeq - 1034618000
RefSeq - 1034618003
RefSeq - 41872583
RefSeq - 530366978
RefSeq - 767913408
RefSeq - NC_000002.12
RefSeq - NG_029769.1
RefSeq - NP_001308572.1
RefSeq - NP_004841.2
RefSeq - XP_005246247.1
RefSeq - XP_011508719.1
RefSeq - XP_016860867.1
RefSeq - 1011750897
RefSeq - NM_001321643.1
RefSeq - NM_004850.4
RefSeq - XM_017005378.2
RefSeq - XM_017005379.2
RefSeq - XM_005246190.3
RefSeq - XM_011510417.2
  
See co-cited genes in PubMed
Warning: Please see the Ensembl gene model ENSG00000134318 to get all the annotations available for this gene.


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001934 positive regulation of protein phosphorylation IMP
 biological_processGO:0006468 protein phosphorylation IDA
 biological_processGO:0006939 smooth muscle contraction TAS
 biological_processGO:0007186 G-protein coupled receptor signaling pathway TAS
 biological_processGO:0007249 I-kappaB kinase/NF-kappaB signaling IMP
 biological_processGO:0007266 Rho protein signal transduction IEA
 biological_processGO:0010595 positive regulation of endothelial cell migration IMP
 biological_processGO:0010613 positive regulation of cardiac muscle hypertrophy ISS
 biological_processGO:0010628 positive regulation of gene expression ISS
 biological_processGO:0010825 positive regulation of centrosome duplication IEA
 biological_processGO:0016525 negative regulation of angiogenesis IMP
 biological_processGO:0018105 peptidyl-serine phosphorylation ISS
 biological_processGO:0018107 peptidyl-threonine phosphorylation IMP
 biological_processGO:0030155 regulation of cell adhesion TAS
 biological_processGO:0030866 cortical actin cytoskeleton organization IMP
 biological_processGO:0032723 positive regulation of connective tissue growth factor production ISS
 biological_processGO:0032956 regulation of actin cytoskeleton organization TAS
 biological_processGO:0035509 negative regulation of myosin-light-chain-phosphatase activity IMP
 biological_processGO:0039694 viral RNA genome replication IMP
 biological_processGO:0042752 regulation of circadian rhythm ISS
 biological_processGO:0043410 positive regulation of MAPK cascade ISS
 biological_processGO:0045616 regulation of keratinocyte differentiation IMP
 biological_processGO:0048010 vascular endothelial growth factor receptor signaling pathway TAS
 biological_processGO:0048013 ephrin receptor signaling pathway TAS
 biological_processGO:0048511 rhythmic process IEA
 biological_processGO:0051246 regulation of protein metabolic process ISS
 biological_processGO:0051298 centrosome duplication IMP
 biological_processGO:0051492 regulation of stress fiber assembly TAS
 biological_processGO:0051893 regulation of focal adhesion assembly TAS
 biological_processGO:0070168 negative regulation of biomineral tissue development ISS
 biological_processGO:0071394 cellular response to testosterone stimulus IMP
 biological_processGO:0071559 response to transforming growth factor beta ISS
 biological_processGO:0072659 protein localization to plasma membrane IMP
 biological_processGO:0090271 positive regulation of fibroblast growth factor production ISS
 biological_processGO:0110061 regulation of angiotensin-activated signaling pathway ISS
 biological_processGO:0150033 negative regulation of protein localization to lysosome IMP
 biological_processGO:1902004 positive regulation of amyloid-beta formation ISS
 biological_processGO:1902961 positive regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process ISS
 biological_processGO:1902966 positive regulation of protein localization to early endosome IMP
 biological_processGO:1902993 positive regulation of amyloid precursor protein catabolic process ISS
 biological_processGO:1903140 regulation of establishment of endothelial barrier IMP
 biological_processGO:1903347 negative regulation of bicellular tight junction assembly IGI
 biological_processGO:1905205 positive regulation of connective tissue replacement ISS
 biological_processGO:1990776 response to angiotensin ISS
 biological_processGO:2000114 regulation of establishment of cell polarity TAS
 biological_processGO:2000145 regulation of cell motility TAS
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005813 centrosome IDA
 cellular_componentGO:0005829 cytosol TAS
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0036464 cytoplasmic ribonucleoprotein granule IDA
 molecular_functionGO:0003723 RNA binding HDA
 molecular_functionGO:0004674 protein serine/threonine kinase activity NAS
 molecular_functionGO:0005198 structural molecule activity NAS
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0017048 Rho GTPase binding IEA
 molecular_functionGO:0046872 metal ion binding IEA
 molecular_functionGO:0072518 Rho-dependent protein serine/threonine kinase activity TAS


Pathways (from Reactome)
Pathway description
No match


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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