9693


Homo sapiens (NCBI)

Features
Gene ID: 9693
  
Biological name :
  
Synonyms : CNrasGEF|NRAPGEP|PDZ-GEF1|PDZGEF1|RA-GEF|RA-GEF-1|Rap-GEP|nRap GEP / RAPGEF2 / Rap guanine nucleotide exchange factor 2
  
Possible biological names infered from orthology :
  
Species: Homo sapiens (NCBI)
  
Chr. number:
Strand:
Band:
Gene start:
Gene end:
  
Corresponding Affymetrix probe sets: 203096_s_at (Human Genome U133 Plus 2.0 Array)   203097_s_at (Human Genome U133 Plus 2.0 Array)   215987_at (Human Genome U133 Plus 2.0 Array)   215992_s_at (Human Genome U133 Plus 2.0 Array)   238176_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: RefSeq - 578809652
RefSeq - 1196924173
RefSeq - 1196926017
RefSeq - 1196926885
RefSeq - 1196926902
RefSeq - 1196928427
RefSeq - 1370487929
RefSeq - 1370487931
RefSeq - 530378443
RefSeq - 530378445
RefSeq - 530378447
RefSeq - 530378449
RefSeq - 1034641902
RefSeq - 578809656
RefSeq - 7657261
RefSeq - 767933100
RefSeq - 767933103
RefSeq - NC_000004.12
RefSeq - NP_001338653.1
RefSeq - NP_001338654.1
RefSeq - NP_001338655.1
RefSeq - NP_001338656.1
RefSeq - NP_001338657.1
RefSeq - NP_055062.1
RefSeq - XP_005263415.1
RefSeq - XP_005263416.1
RefSeq - XP_005263417.1
RefSeq - XP_005263418.1
RefSeq - XP_006714483.1
RefSeq - XP_006714485.1
RefSeq - XP_011530727.1
RefSeq - XP_011530728.1
RefSeq - XP_016864345.1
RefSeq - XP_024310054.1
RefSeq - XP_024310055.1
RefSeq - NM_001351724.1
RefSeq - NM_001351725.1
RefSeq - NM_001351726.1
RefSeq - NM_001351727.1
RefSeq - NM_001351728.1
RefSeq - NM_014247.2
RefSeq - XM_006714422.4
RefSeq - XM_011532425.2
RefSeq - XM_011532426.2
RefSeq - XM_017008856.2
RefSeq - XM_024454286.1
RefSeq - XM_024454287.1
RefSeq - XM_005263358.3
RefSeq - XM_005263359.4
RefSeq - XM_005263360.3
RefSeq - XM_005263361.3
RefSeq - XM_006714420.3
  
See co-cited genes in PubMed
Warning: Please see the Ensembl gene model ENSG00000109756 to get all the annotations available for this gene.


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000165 MAPK cascade TAS
 biological_processGO:0001568 blood vessel development ISS
 biological_processGO:0001764 neuron migration ISS
 biological_processGO:0007186 G-protein coupled receptor signaling pathway IDA
 biological_processGO:0007218 neuropeptide signaling pathway IDA
 biological_processGO:0007264 small GTPase mediated signal transduction TAS
 biological_processGO:0008285 negative regulation of cell proliferation IDA
 biological_processGO:0010976 positive regulation of neuron projection development ISS
 biological_processGO:0019933 cAMP-mediated signaling NAS
 biological_processGO:0021591 ventricular system development ISS
 biological_processGO:0021884 forebrain neuron development ISS
 biological_processGO:0030033 microvillus assembly IGI
 biological_processGO:0031175 neuron projection development IDA
 biological_processGO:0031547 brain-derived neurotrophic factor receptor signaling pathway ISS
 biological_processGO:0032092 positive regulation of protein binding ISS
 biological_processGO:0032486 Rap protein signal transduction IMP
 biological_processGO:0035556 intracellular signal transduction TAS
 biological_processGO:0038180 nerve growth factor signaling pathway ISS
 biological_processGO:0043547 positive regulation of GTPase activity IMP
 biological_processGO:0043950 positive regulation of cAMP-mediated signaling IDA
 biological_processGO:0045860 positive regulation of protein kinase activity IDA
 biological_processGO:0048022 negative regulation of melanin biosynthetic process ISS
 biological_processGO:0048167 regulation of synaptic plasticity ISS
 biological_processGO:0050774 negative regulation of dendrite morphogenesis IDA
 biological_processGO:0061028 establishment of endothelial barrier IMP
 biological_processGO:0070374 positive regulation of ERK1 and ERK2 cascade IDA
 biological_processGO:0071320 cellular response to cAMP IDA
 biological_processGO:0071321 cellular response to cGMP IDA
 biological_processGO:0071880 adenylate cyclase-activating adrenergic receptor signaling pathway IDA
 biological_processGO:0072659 protein localization to plasma membrane IMP
 biological_processGO:0090557 establishment of endothelial intestinal barrier IMP
 biological_processGO:1901888 regulation of cell junction assembly IMP
 biological_processGO:1990090 cellular response to nerve growth factor stimulus ISS
 biological_processGO:2000481 positive regulation of cAMP-dependent protein kinase activity IDA
 biological_processGO:2000670 positive regulation of dendritic cell apoptotic process IDA
 biological_processGO:2001214 positive regulation of vasculogenesis ISS
 biological_processGO:2001224 positive regulation of neuron migration ISS
 cellular_componentGO:0005737 cytoplasm IDA
 cellular_componentGO:0005770 late endosome IDA
 cellular_componentGO:0005829 cytosol TAS
 cellular_componentGO:0005886 plasma membrane ISS
 cellular_componentGO:0005887 integral component of plasma membrane NAS
 cellular_componentGO:0005911 cell-cell junction ISS
 cellular_componentGO:0005923 bicellular tight junction IDA
 cellular_componentGO:0016020 membrane IDA
 cellular_componentGO:0016324 apical plasma membrane IDA
 cellular_componentGO:0030139 endocytic vesicle IDA
 cellular_componentGO:0032991 protein-containing complex ISS
 cellular_componentGO:0043005 neuron projection ISS
 cellular_componentGO:0043025 neuronal cell body ISS
 cellular_componentGO:0045202 synapse ISS
 cellular_componentGO:0048471 perinuclear region of cytoplasm IDA
 molecular_functionGO:0005088 Ras guanyl-nucleotide exchange factor activity TAS
 molecular_functionGO:0005096 GTPase activator activity IDA
 molecular_functionGO:0005509 calcium ion binding NAS
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0017034 Rap guanyl-nucleotide exchange factor activity IMP
 molecular_functionGO:0019992 diacylglycerol binding NAS
 molecular_functionGO:0030165 PDZ domain binding IDA
 molecular_functionGO:0030552 cAMP binding IDA
 molecular_functionGO:0030553 cGMP binding IDA
 molecular_functionGO:0031697 beta-1 adrenergic receptor binding IDA
 molecular_functionGO:0050699 WW domain binding IDA
 molecular_functionGO:0070300 phosphatidic acid binding IDA


Pathways (from Reactome)
Pathway description
No match


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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