ENSDARG00000000018


Danio rerio

Features
Gene ID: ENSDARG00000000018
  
Biological name :nrf1
  
Synonyms : nrf1 / nuclear respiratory factor 1 / Q90X44
  
Possible biological names infered from orthology : Q16656 / Q9WU00
  
Species: Danio rerio
  
Chr. number: 4
Strand: -1
Band:
Gene start: 15081385
Gene end: 15103696
  
Corresponding Affymetrix probe sets: Dr.8179.1.S1_at (Zebrafish Array)   NM_131680_at (Zebrafish Genome Array with custom cdf files)   
  
Cross references: Ensembl peptide - ENSDARP00000116798
Ensembl peptide - ENSDARP00000149440
NCBI entrez gene - 64604     See in Manteia.
RefSeq - NM_131680
RefSeq - NM_001328540
RefSeq Peptide - NP_001315469
RefSeq Peptide - NP_571755
swissprot - Q90X44
ZFIN ID - ZDB-GENE-001221-1
Ensembl - ENSDARG00000000018
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 NRF1ENSGALG00000040060Gallus gallus
 NRF1ENSG00000106459Homo sapiens
 Nrf1ENSMUSG00000058440Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR019525  Nuclear respiratory factor 1, NLS/DNA-binding, dimerisation domain
 IPR019526  Nuclear respiratory factor-1, activation binding domain
 IPR023753  FAD/NAD(P)-binding domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001895 retina homeostasis IMP
 biological_processGO:0003407 neural retina development IMP
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0007275 multicellular organism development IMP
 biological_processGO:0014823 response to activity IDA
 biological_processGO:0045494 photoreceptor cell maintenance IMP
 biological_processGO:0060041 retina development in camera-type eye IMP
 biological_processGO:0070417 cellular response to cold IDA
 cellular_componentGO:0005634 nucleus IEA
 molecular_functionGO:0003677 DNA binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000107 eye eye decreased size , abnormal
eye quality , abnormal
Show

 ZFA:0000119 retinal inner nuclear layer retinal inner nuclear layer morphology , abnormal
Show

 ZFA:0000143 retinal photoreceptor layer retinal photoreceptor layer quality , abnormal
retinal photoreceptor layer lacks parts or has fewer parts of type photoreceptor cell , abnormal
retinal photoreceptor layer decreased thickness , abnormal
Show

 ZFA:0000152 retina retina cell death increased occurrence , abnormal
retina cell disorganized , abnormal
Show

 ZFA:0000282 sensory system sensory system quality , abnormal
Show

 ZFA:0000396 nervous system nervous system quality , abnormal
Show

 ZFA:0009127 photoreceptor cell photoreceptor cell photoreceptor outer segment deformed , abnormal
photoreceptor cell circular , abnormal
photoreceptor cell apoptotic , abnormal
Show

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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