ENSDARG00000000606


Danio rerio

Features
Gene ID: ENSDARG00000000606
  
Biological name :dnah6
  
Synonyms : dnah6 / dynein, axonemal, heavy chain 6
  
Possible biological names infered from orthology : Q9C0G6
  
Species: Danio rerio
  
Chr. number: 1
Strand: 1
Band:
Gene start: 22002649
Gene end: 22235421
  
Corresponding Affymetrix probe sets: Dr.15553.1.A1_at (Zebrafish Array)   
  
Cross references: Ensembl peptide - ENSDARP00000054387
Ensembl peptide - ENSDARP00000122341
Ensembl peptide - ENSDARP00000117837
NCBI entrez gene - 100148193     See in Manteia.
RefSeq - XM_021476325
swissprot - E9QH47
swissprot - E9QEF8
swissprot - F1Q6J7
ZFIN ID - ZDB-GENE-030616-623
Ensembl - ENSDARG00000000606
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 DNAH6ENSG00000115423Homo sapiens
 Dnah6ENSMUSG00000052861Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
dnah7 / dynein, axonemal, heavy chain 7 / Dnah7a* / Dnah7c* / Q8WXX0*ENSDARG0000006016536
dnah1 / dynein, axonemal, heavy chain 1 / E9Q8T7* / Q9P2D7* / Dynein heavy chain 1, axonemal *ENSDARG0000010011536
dnah3 / dynein axonemal heavy chain 3 / Q8BW94* / Dynein heavy chain 3, axonemal *ENSDARG0000006846835
dnah2 / dynein, axonemal, heavy chain 2 / P0C6F1* / Q9P225* / Dynein heavy chain 2, axonemal *ENSDARG0000008735235
dnah12 / dynein, axonemal, heavy chain 12ENSDARG0000005998735
si:dkeyp-86b9.1 / Dnah10*ENSDARG0000006148631
dnah9l / dynein, axonemal, heavy polypeptide 9 likeENSDARG0000006263029
dnah5 / dynein, axonemal, heavy chain 5ENSDARG0000008737328
dnah11 / dynein, axonemal, heavy chain 11 / Q96DT5*ENSDARG0000009428226


Protein motifs (from Interpro)
Interpro ID Name
 IPR003593  AAA+ ATPase domain
 IPR004273  Dynein heavy chain domain
 IPR011704  ATPase, dynein-related, AAA domain
 IPR013602  Dynein heavy chain, domain-2
 IPR024317  Dynein heavy chain, AAA module D4
 IPR024743  Dynein heavy chain, coiled coil stalk
 IPR026980  Dynein heavy chain 6, axonemal
 IPR026983  Dynein heavy chain
 IPR027417  P-loop containing nucleoside triphosphate hydrolase
 IPR035699  Dynein heavy chain, hydrolytic ATP-binding dynein motor region D1
 IPR035706  Dynein heavy chain, ATP-binding dynein motor region D5


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001539 cilium or flagellum-dependent cell motility IEA
 biological_processGO:0007018 microtubule-based movement IEA
 biological_processGO:0060271 cilium assembly IBA
 biological_processGO:0060287 epithelial cilium movement involved in determination of left/right asymmetry IMP
 biological_processGO:0061371 determination of heart left/right asymmetry IMP
 cellular_componentGO:0005858 axonemal dynein complex IEA
 cellular_componentGO:0005929 cilium IBA
 cellular_componentGO:0030286 dynein complex IEA
 molecular_functionGO:0003777 microtubule motor activity IEA
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0008569 ATP-dependent microtubule motor activity, minus-end-directed IBA
 molecular_functionGO:0016887 ATPase activity IEA
 molecular_functionGO:0045503 dynein light chain binding IBA
 molecular_functionGO:0045505 dynein intermediate chain binding IBA
 molecular_functionGO:0051959 dynein light intermediate chain binding IBA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000001 Kupffer s vesicle Kupffers vesicle epithelial cilium movement decreased process quality , abnormal
Kupffers vesicle cilium decreased length , abnormal
Show

 ZFA:0000054 pericardium pericardium edematous , abnormal
Show

 ZFA:0000114 heart heart mislocalised , abnormal
Show

 ZFA:0001117 post-vent region post-vent region curved , abnormal
Show

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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