ENSG00000115423


Homo sapiens

Features
Gene ID: ENSG00000115423
  
Biological name :DNAH6
  
Synonyms : DNAH6 / dynein axonemal heavy chain 6 / Q9C0G6
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 2
Strand: 1
Band: p11.2
Gene start: 84516455
Gene end: 84819589
  
Corresponding Affymetrix probe sets: 1552957_at (Human Genome U133 Plus 2.0 Array)   1553362_at (Human Genome U133 Plus 2.0 Array)   1561616_a_at (Human Genome U133 Plus 2.0 Array)   1561617_at (Human Genome U133 Plus 2.0 Array)   1565337_at (Human Genome U133 Plus 2.0 Array)   1565338_x_at (Human Genome U133 Plus 2.0 Array)   215341_at (Human Genome U133 Plus 2.0 Array)   234893_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000237449
Ensembl peptide - ENSP00000374045
NCBI entrez gene - 1768     See in Manteia.
OMIM - 603336
RefSeq - XM_017003523
RefSeq - NM_001370
RefSeq - XM_017003521
RefSeq - XM_017003522
RefSeq - XM_006711956
RefSeq - XM_011532649
RefSeq - XM_011532650
RefSeq - XM_011532652
RefSeq - XM_011532653
RefSeq - XM_011532654
RefSeq - XM_011532655
RefSeq - XM_011532657
RefSeq Peptide - NP_001361
swissprot - Q9C0G6
Ensembl - ENSG00000115423
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 dnah6ENSDARG00000000606Danio rerio
 Dnah6ENSMUSG00000052861Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
DNAH1 / Q9P2D7 / dynein axonemal heavy chain 1ENSG0000011484136
DNAH7 / Q8WXX0 / dynein axonemal heavy chain 7ENSG0000011899736
DNAH2 / Q9P225 / dynein axonemal heavy chain 2ENSG0000018391434
DNAH17 / Q9UFH2 / dynein axonemal heavy chain 17ENSG0000018777529
DNAH11 / Q96DT5 / dynein axonemal heavy chain 11ENSG0000010587729
DNAH8 / Q96JB1 / dynein axonemal heavy chain 8ENSG0000012472128
Q14204 / DYNC1H1 / dynein cytoplasmic 1 heavy chain 1ENSG0000019710224
DNAH14 / Q0VDD8 / dynein axonemal heavy chain 14ENSG000001858422


Protein motifs (from Interpro)
Interpro ID Name
 IPR003593  AAA+ ATPase domain
 IPR004273  Dynein heavy chain domain
 IPR011704  ATPase, dynein-related, AAA domain
 IPR013602  Dynein heavy chain, domain-2
 IPR024317  Dynein heavy chain, AAA module D4
 IPR024743  Dynein heavy chain, coiled coil stalk
 IPR026980  Dynein heavy chain 6, axonemal
 IPR026983  Dynein heavy chain
 IPR027417  P-loop containing nucleoside triphosphate hydrolase
 IPR035699  Dynein heavy chain, hydrolytic ATP-binding dynein motor region D1
 IPR035706  Dynein heavy chain, ATP-binding dynein motor region D5


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001539 cilium or flagellum-dependent cell motility IEA
 biological_processGO:0007018 microtubule-based movement IBA
 biological_processGO:0060271 cilium assembly IBA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005856 cytoskeleton IEA
 cellular_componentGO:0005858 axonemal dynein complex IEA
 cellular_componentGO:0005874 microtubule IEA
 cellular_componentGO:0005929 cilium IBA
 cellular_componentGO:0030286 dynein complex IBA
 cellular_componentGO:0042995 cell projection IEA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0003774 motor activity IEA
 molecular_functionGO:0003777 microtubule motor activity IEA
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0008569 ATP-dependent microtubule motor activity, minus-end-directed IBA
 molecular_functionGO:0016887 ATPase activity IEA
 molecular_functionGO:0045503 dynein light chain binding IBA
 molecular_functionGO:0045505 dynein intermediate chain binding IBA
 molecular_functionGO:0051959 dynein light intermediate chain binding IBA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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