ENSG00000118997


Homo sapiens

Features
Gene ID: ENSG00000118997
  
Biological name :DNAH7
  
Synonyms : DNAH7 / dynein axonemal heavy chain 7 / Q8WXX0
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 2
Strand: -1
Band: q32.3
Gene start: 195737703
Gene end: 196068812
  
Corresponding Affymetrix probe sets: 214222_at (Human Genome U133 Plus 2.0 Array)   234476_at (Human Genome U133 Plus 2.0 Array)   234727_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000311273
Ensembl peptide - ENSP00000386912
Ensembl peptide - ENSP00000407444
Ensembl peptide - ENSP00000409732
Ensembl peptide - ENSP00000386260
NCBI entrez gene - 56171     See in Manteia.
OMIM - 610061
RefSeq - XM_017004504
RefSeq - XM_011511492
RefSeq - XM_011511493
RefSeq - XM_011511494
RefSeq - XM_011511495
RefSeq - NM_018897
RefSeq - XM_011511487
RefSeq - XM_011511488
RefSeq - XM_011511489
RefSeq - XM_011511490
RefSeq - XM_011511491
RefSeq Peptide - NP_061720
swissprot - H7C362
swissprot - C9JUY3
swissprot - Q8WXX0
Ensembl - ENSG00000118997
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 dnah7ENSDARG00000060165Danio rerio
 DNAH7ENSGALG00000007841Gallus gallus
 Dnah7aENSMUSG00000096141Mus musculus
 Dnah7cENSMUSG00000101337Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
DNAH1 / Q9P2D7 / dynein axonemal heavy chain 1ENSG0000011484142
DNAH6 / Q9C0G6 / dynein axonemal heavy chain 6ENSG0000011542337
DNAH2 / Q9P225 / dynein axonemal heavy chain 2ENSG0000018391435
DNAH17 / Q9UFH2 / dynein axonemal heavy chain 17ENSG0000018777531
DNAH11 / Q96DT5 / dynein axonemal heavy chain 11ENSG0000010587730
DNAH8 / Q96JB1 / dynein axonemal heavy chain 8ENSG0000012472129
Q14204 / DYNC1H1 / dynein cytoplasmic 1 heavy chain 1ENSG0000019710224
DNAH14 / Q0VDD8 / dynein axonemal heavy chain 14ENSG000001858421


Protein motifs (from Interpro)
Interpro ID Name
 IPR002048  EF-hand domain
 IPR003593  AAA+ ATPase domain
 IPR004273  Dynein heavy chain domain
 IPR013602  Dynein heavy chain, domain-2
 IPR018247  EF-Hand 1, calcium-binding site
 IPR024317  Dynein heavy chain, AAA module D4
 IPR024743  Dynein heavy chain, coiled coil stalk
 IPR026983  Dynein heavy chain
 IPR027417  P-loop containing nucleoside triphosphate hydrolase
 IPR035699  Dynein heavy chain, hydrolytic ATP-binding dynein motor region D1
 IPR035706  Dynein heavy chain, ATP-binding dynein motor region D5


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0003341 cilium movement IMP
 biological_processGO:0007018 microtubule-based movement IEA
 biological_processGO:0036159 inner dynein arm assembly IMP
 biological_processGO:0060285 cilium-dependent cell motility NAS
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005829 cytosol IDA
 cellular_componentGO:0005856 cytoskeleton IEA
 cellular_componentGO:0005858 axonemal dynein complex NAS
 cellular_componentGO:0005874 microtubule IEA
 cellular_componentGO:0005929 cilium IDA
 cellular_componentGO:0030286 dynein complex IEA
 cellular_componentGO:0036156 inner dynein arm IMP
 cellular_componentGO:0042995 cell projection IEA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0003774 motor activity IEA
 molecular_functionGO:0003777 microtubule motor activity IEA
 molecular_functionGO:0005509 calcium ion binding IEA
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0008569 ATP-dependent microtubule motor activity, minus-end-directed IBA
 molecular_functionGO:0045503 dynein light chain binding IBA
 molecular_functionGO:0045505 dynein intermediate chain binding IBA
 molecular_functionGO:0051959 dynein light intermediate chain binding IBA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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