ENSG00000183914


Homo sapiens

Features
Gene ID: ENSG00000183914
  
Biological name :DNAH2
  
Synonyms : DNAH2 / dynein axonemal heavy chain 2 / Q9P225
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 17
Strand: 1
Band: p13.1
Gene start: 7717354
Gene end: 7833744
  
Corresponding Affymetrix probe sets: 215840_at (Human Genome U133 Plus 2.0 Array)   239499_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000458355
Ensembl peptide - ENSP00000461273
Ensembl peptide - ENSP00000461726
Ensembl peptide - ENSP00000373825
Ensembl peptide - ENSP00000460245
NCBI entrez gene - 146754     See in Manteia.
OMIM - 603333
RefSeq - XM_017024219
RefSeq - XM_011523667
RefSeq - XM_011523668
RefSeq - XM_011523669
RefSeq - XM_011523670
RefSeq - XM_017024218
RefSeq - NM_001303270
RefSeq - NM_020877
RefSeq - XM_011523663
RefSeq - XM_011523664
RefSeq - XM_011523666
RefSeq Peptide - NP_001290199
RefSeq Peptide - NP_065928
swissprot - I3L520
swissprot - Q9P225
swissprot - I3L4H9
Ensembl - ENSG00000183914
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 dnah2ENSDARG00000087352Danio rerio
 Dnah2ENSMUSG00000005237Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
DNAH1 / Q9P2D7 / dynein axonemal heavy chain 1ENSG0000011484133
DNAH7 / Q8WXX0 / dynein axonemal heavy chain 7ENSG0000011899732
DNAH6 / Q9C0G6 / dynein axonemal heavy chain 6ENSG0000011542332
DNAH11 / Q96DT5 / dynein axonemal heavy chain 11ENSG0000010587731
DNAH17 / Q9UFH2 / dynein axonemal heavy chain 17ENSG0000018777531
DNAH8 / Q96JB1 / dynein axonemal heavy chain 8ENSG0000012472130
Q14204 / DYNC1H1 / dynein cytoplasmic 1 heavy chain 1ENSG0000019710224
DNAH14 / Q0VDD8 / dynein axonemal heavy chain 14ENSG000001858421


Protein motifs (from Interpro)
Interpro ID Name
 IPR003593  AAA+ ATPase domain
 IPR004273  Dynein heavy chain domain
 IPR011704  ATPase, dynein-related, AAA domain
 IPR013594  Dynein heavy chain, domain-1
 IPR013602  Dynein heavy chain, domain-2
 IPR024317  Dynein heavy chain, AAA module D4
 IPR024743  Dynein heavy chain, coiled coil stalk
 IPR026983  Dynein heavy chain
 IPR027417  P-loop containing nucleoside triphosphate hydrolase
 IPR035699  Dynein heavy chain, hydrolytic ATP-binding dynein motor region D1
 IPR035706  Dynein heavy chain, ATP-binding dynein motor region D5


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007018 microtubule-based movement IBA
 biological_processGO:0060285 cilium-dependent cell motility NAS
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005856 cytoskeleton IEA
 cellular_componentGO:0005858 axonemal dynein complex NAS
 cellular_componentGO:0005874 microtubule IEA
 cellular_componentGO:0005929 cilium IEA
 cellular_componentGO:0030286 dynein complex IBA
 cellular_componentGO:0031514 motile cilium IBA
 cellular_componentGO:0042995 cell projection IEA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0003774 motor activity IEA
 molecular_functionGO:0003777 microtubule motor activity NAS
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0008569 ATP-dependent microtubule motor activity, minus-end-directed IBA
 molecular_functionGO:0016887 ATPase activity IEA
 molecular_functionGO:0045503 dynein light chain binding IBA
 molecular_functionGO:0045505 dynein intermediate chain binding IBA
 molecular_functionGO:0051959 dynein light intermediate chain binding IBA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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