ENSMUSG00000005237


Mus musculus

Features
Gene ID: ENSMUSG00000005237
  
Biological name :Dnah2
  
Synonyms : Dnah2 / Dynein heavy chain 2, axonemal / P0C6F1
  
Possible biological names infered from orthology : dynein axonemal heavy chain 2 / Q9P225
  
Species: Mus musculus
  
Chr. number: 11
Strand: -1
Band: B3
Gene start: 69420809
Gene end: 69549110
  
Corresponding Affymetrix probe sets: 10387397 (MoGene1.0st)   1438763_at (Mouse Genome 430 2.0 Array)   1454103_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000146424
Ensembl peptide - ENSMUSP00000047329
Ensembl peptide - ENSMUSP00000104299
NCBI entrez gene - 327954     See in Manteia.
MGI - MGI:107731
RefSeq - XM_017314611
RefSeq - XM_011249076
RefSeq - XM_011249077
RefSeq - XM_011249079
RefSeq - XM_011249081
RefSeq - XM_017314610
RefSeq - NM_001081330
RefSeq - XM_006533552
RefSeq - XM_006533554
RefSeq - XM_006533559
RefSeq - XM_006533560
RefSeq - XM_011249074
RefSeq - XM_011249075
RefSeq Peptide - NP_001074799
swissprot - D3Z667
swissprot - A0A140LHI3
swissprot - P0C6F1
swissprot - Q5F222
Ensembl - ENSMUSG00000005237
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 dnah2ENSDARG00000087352Danio rerio
 DNAH2ENSG00000183914Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Dnah10ENSMUSG0000003801133
Dnah1 / E9Q8T7 / Dynein heavy chain 1, axonemal / Q9P2D7* / dynein axonemal heavy chain 1*ENSMUSG0000001902733
Dnah12ENSMUSG0000002187932
Dnah7c / DNAH7* / Q8WXX0* / dynein axonemal heavy chain 7*ENSMUSG0000010133732
Dnah6 / dynein axonemal heavy chain 6 / Q9C0G6*ENSMUSG0000005286132
Dnah7a / DNAH7* / Q8WXX0* / dynein axonemal heavy chain 7*ENSMUSG0000009614132
Dnah3 / Q8BW94 / Dynein heavy chain 3, axonemal ENSMUSG0000005227331
Dnah17 / dynein axonemal heavy chain 17 / Q9UFH2*ENSMUSG0000003398731
Dnah5 / Q8VHE6 / Dynein heavy chain 5, axonemal ENSMUSG0000002226230
Dnah11 / dynein axonemal heavy chain 11 / Q96DT5*ENSMUSG0000001858130
Dnah8 / Q91XQ0 / Dynein heavy chain 8, axonemal / Q96JB1* / dynein axonemal heavy chain 8*ENSMUSG0000003382629
Dnah14 / Q0VDD8* / dynein axonemal heavy chain 14*ENSMUSG0000004736926
Q9JHU4 / Dync1h1 / Cytoplasmic dynein 1 heavy chain 1 / Q14204* / dynein cytoplasmic 1 heavy chain 1*ENSMUSG0000001870724


Protein motifs (from Interpro)
Interpro ID Name
 IPR003593  AAA+ ATPase domain
 IPR004273  Dynein heavy chain domain
 IPR011704  ATPase, dynein-related, AAA domain
 IPR013594  Dynein heavy chain, domain-1
 IPR013602  Dynein heavy chain, domain-2
 IPR024317  Dynein heavy chain, AAA module D4
 IPR024743  Dynein heavy chain, coiled coil stalk
 IPR026983  Dynein heavy chain
 IPR027417  P-loop containing nucleoside triphosphate hydrolase
 IPR035699  Dynein heavy chain, hydrolytic ATP-binding dynein motor region D1
 IPR035706  Dynein heavy chain, ATP-binding dynein motor region D5


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007018 microtubule-based movement IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005856 cytoskeleton IEA
 cellular_componentGO:0005874 microtubule IEA
 cellular_componentGO:0005929 cilium IEA
 cellular_componentGO:0030286 dynein complex IEA
 cellular_componentGO:0031514 motile cilium IDA
 cellular_componentGO:0036156 inner dynein arm ISM
 cellular_componentGO:0042995 cell projection IEA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0003774 motor activity IEA
 molecular_functionGO:0003777 microtubule motor activity IEA
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0008569 ATP-dependent microtubule motor activity, minus-end-directed IBA
 molecular_functionGO:0016887 ATPase activity IEA
 molecular_functionGO:0045503 dynein light chain binding IBA
 molecular_functionGO:0045505 dynein intermediate chain binding IBA
 molecular_functionGO:0051959 dynein light intermediate chain binding IBA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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