ENSG00000185842


Homo sapiens

Features
Gene ID: ENSG00000185842
  
Biological name :DNAH14
  
Synonyms : DNAH14 / dynein axonemal heavy chain 14 / Q0VDD8
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 1
Strand: 1
Band: q42.12
Gene start: 224896262
Gene end: 225399292
  
Corresponding Affymetrix probe sets: 1554540_at (Human Genome U133 Plus 2.0 Array)   1567861_at (Human Genome U133 Plus 2.0 Array)   1567862_at (Human Genome U133 Plus 2.0 Array)   242283_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000429568
Ensembl peptide - ENSP00000429122
Ensembl peptide - ENSP00000492319
Ensembl peptide - ENSP00000328980
Ensembl peptide - ENSP00000332424
Ensembl peptide - ENSP00000355813
Ensembl peptide - ENSP00000355814
Ensembl peptide - ENSP00000355815
Ensembl peptide - ENSP00000383737
Ensembl peptide - ENSP00000392061
Ensembl peptide - ENSP00000398678
Ensembl peptide - ENSP00000409472
Ensembl peptide - ENSP00000409971
Ensembl peptide - ENSP00000414402
Ensembl peptide - ENSP00000414699
NCBI entrez gene - 127602     See in Manteia.
OMIM - 603341
RefSeq - XM_017000299
RefSeq - XM_011544066
RefSeq - XM_011544067
RefSeq - XM_011544069
RefSeq - XM_011544070
RefSeq - XM_011544071
RefSeq - XM_011544072
RefSeq - XM_011544073
RefSeq - XM_011544074
RefSeq - XM_011544076
RefSeq - XM_011544079
RefSeq - XM_017000295
RefSeq - XM_017000296
RefSeq - XM_017000297
RefSeq - XM_017000298
RefSeq - NM_001145154
RefSeq - NM_001349911
RefSeq - NM_001373
RefSeq - NM_144989
RefSeq - XM_006711735
RefSeq - XM_011544057
RefSeq - XM_011544058
RefSeq - XM_011544059
RefSeq - XM_011544061
RefSeq - XM_011544062
RefSeq - XM_011544063
RefSeq - XM_011544064
RefSeq - XM_011544065
RefSeq Peptide - NP_001364
RefSeq Peptide - NP_659426
RefSeq Peptide - NP_001138626
RefSeq Peptide - NP_001336840
swissprot - H7C374
swissprot - H7C3Z3
swissprot - H9KV43
swissprot - H0YBB1
swissprot - Q0VDD8
swissprot - A0A1W2PR53
swissprot - M9MMK7
swissprot - H0YBI3
swissprot - H7BXS7
swissprot - H7C164
Ensembl - ENSG00000185842
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 Dnah14ENSMUSG00000047369Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
DNAH6 / Q9C0G6 / dynein axonemal heavy chain 6ENSG0000011542320
DNAH2 / Q9P225 / dynein axonemal heavy chain 2ENSG0000018391411
DNAH1 / Q9P2D7 / dynein axonemal heavy chain 1ENSG0000011484111
DNAH7 / Q8WXX0 / dynein axonemal heavy chain 7ENSG000001189979
DNAH11 / Q96DT5 / dynein axonemal heavy chain 11ENSG000001058779
Q14204 / DYNC1H1 / dynein cytoplasmic 1 heavy chain 1ENSG000001971027
DNAH8 / Q96JB1 / dynein axonemal heavy chain 8ENSG000001247217
DNAH17 / Q9UFH2 / dynein axonemal heavy chain 17ENSG000001877757


Protein motifs (from Interpro)
Interpro ID Name
 IPR003593  AAA+ ATPase domain
 IPR004273  Dynein heavy chain domain
 IPR013602  Dynein heavy chain, domain-2
 IPR024317  Dynein heavy chain, AAA module D4
 IPR024743  Dynein heavy chain, coiled coil stalk
 IPR026980  Dynein heavy chain 6, axonemal
 IPR026983  Dynein heavy chain
 IPR027417  P-loop containing nucleoside triphosphate hydrolase
 IPR035699  Dynein heavy chain, hydrolytic ATP-binding dynein motor region D1
 IPR035706  Dynein heavy chain, ATP-binding dynein motor region D5


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001539 cilium or flagellum-dependent cell motility IEA
 biological_processGO:0007018 microtubule-based movement IBA
 biological_processGO:0060271 cilium assembly IBA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005856 cytoskeleton IEA
 cellular_componentGO:0005858 axonemal dynein complex IEA
 cellular_componentGO:0005874 microtubule IEA
 cellular_componentGO:0005929 cilium IBA
 cellular_componentGO:0030286 dynein complex IBA
 cellular_componentGO:0042995 cell projection IEA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0003774 motor activity IEA
 molecular_functionGO:0003777 microtubule motor activity IEA
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0008569 ATP-dependent microtubule motor activity, minus-end-directed IBA
 molecular_functionGO:0016887 ATPase activity IEA
 molecular_functionGO:0045503 dynein light chain binding IBA
 molecular_functionGO:0045505 dynein intermediate chain binding IBA
 molecular_functionGO:0051959 dynein light intermediate chain binding IBA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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