ENSDARG00000000853


Danio rerio

Features
Gene ID: ENSDARG00000000853
  
Biological name :dstyk
  
Synonyms : dstyk / dual serine/threonine and tyrosine protein kinase / Q4VSN1
  
Possible biological names infered from orthology : Q6XUX1 / Q6XUX3
  
Species: Danio rerio
  
Chr. number: 22
Strand: -1
Band:
Gene start: 472327
Gene end: 506522
  
Corresponding Affymetrix probe sets: Dr.13169.1.S1_at (Zebrafish Array)   NM_205627_at (Zebrafish Genome Array with custom cdf files)   
  
Cross references: Ensembl peptide - ENSDARP00000067636
Ensembl peptide - ENSDARP00000097423
NCBI entrez gene - 402922     See in Manteia.
RefSeq - NM_205627
RefSeq Peptide - NP_991190
swissprot - Q4VSN1
ZFIN ID - ZDB-GENE-040826-2
Ensembl - ENSDARG00000000853
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 DSTYKENSGALG00000041123Gallus gallus
 DSTYKENSG00000133059Homo sapiens
 DstykENSMUSG00000042046Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR000719  Protein kinase domain
 IPR008271  Serine/threonine-protein kinase, active site
 IPR011009  Protein kinase-like domain superfamily
 IPR017441  Protein kinase, ATP binding site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006468 protein phosphorylation IBA
 biological_processGO:0007275 multicellular organism development IEA
 biological_processGO:0016310 phosphorylation IEA
 biological_processGO:0018108 peptidyl-tyrosine phosphorylation IEA
 biological_processGO:0035556 intracellular signal transduction IBA
 biological_processGO:0048568 embryonic organ development IMP
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005829 cytosol IBA
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016323 basolateral plasma membrane IEA
 cellular_componentGO:0016324 apical plasma membrane IEA
 cellular_componentGO:0030054 cell junction IEA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0004672 protein kinase activity IEA
 molecular_functionGO:0004674 protein serine/threonine kinase activity IEA
 molecular_functionGO:0004712 protein serine/threonine/tyrosine kinase activity IEA
 molecular_functionGO:0004713 protein tyrosine kinase activity IEA
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0016301 kinase activity IEA
 molecular_functionGO:0016740 transferase activity IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000135 notochord notochord deformed , abnormal
Show

 ZFA:0000155 somite somite condensed , abnormal
Show

 ZFA:0001055 pronephric duct opening pronephric duct opening closed , abnormal
Show

 ZFA:0001094 whole organism whole organism anterior-posterior axis undulate , abnormal
whole organism edematous , abnormal
whole organism decreased life span , abnormal
whole organism lacks all parts of type ventral fin fold , abnormal
whole organism anterior-posterior axis increased curvature , abnormal
Show

 ZFA:0001612 pharyngeal arch 1 pharyngeal arch 1 malformed , abnormal
Show

 ZFA:0005781 cloaca cloaca malformed , abnormal
Show

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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