ENSMUSG00000042046


Mus musculus

Features
Gene ID: ENSMUSG00000042046
  
Biological name :Dstyk
  
Synonyms : Dstyk / Dual serine/threonine and tyrosine protein kinase / Q6XUX1
  
Possible biological names infered from orthology : Q6XUX3
  
Species: Mus musculus
  
Chr. number: 1
Strand: 1
Band: E4
Gene start: 132417555
Gene end: 132466958
  
Corresponding Affymetrix probe sets: 10349793 (MoGene1.0st)   1436300_at (Mouse Genome 430 2.0 Array)   1436301_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000035358
Ensembl peptide - ENSMUSP00000140376
Ensembl peptide - ENSMUSP00000139652
NCBI entrez gene - 213452     See in Manteia.
MGI - MGI:1925064
RefSeq - NM_172516
RefSeq - XM_006529356
RefSeq Peptide - NP_766104
swissprot - A0A087WQX0
swissprot - Q6XUX1
swissprot - A0A087WP69
Ensembl - ENSMUSG00000042046
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 dstykENSDARG00000000853Danio rerio
 DSTYKENSGALG00000041123Gallus gallus
 DSTYKENSG00000133059Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR000719  Protein kinase domain
 IPR001245  Serine-threonine/tyrosine-protein kinase, catalytic domain
 IPR008271  Serine/threonine-protein kinase, active site
 IPR011009  Protein kinase-like domain superfamily
 IPR017441  Protein kinase, ATP binding site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006468 protein phosphorylation IEA
 biological_processGO:0016310 phosphorylation IEA
 biological_processGO:0018108 peptidyl-tyrosine phosphorylation IEA
 biological_processGO:0033674 positive regulation of kinase activity IEA
 biological_processGO:0035556 intracellular signal transduction IBA
 biological_processGO:0043066 negative regulation of apoptotic process IEA
 biological_processGO:0044344 cellular response to fibroblast growth factor stimulus IEA
 biological_processGO:0045743 positive regulation of fibroblast growth factor receptor signaling pathway IEA
 biological_processGO:0070374 positive regulation of ERK1 and ERK2 cascade IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005829 cytosol IBA
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016323 basolateral plasma membrane IEA
 cellular_componentGO:0016324 apical plasma membrane IEA
 cellular_componentGO:0030054 cell junction IEA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0004672 protein kinase activity IEA
 molecular_functionGO:0004674 protein serine/threonine kinase activity IBA
 molecular_functionGO:0004712 protein serine/threonine/tyrosine kinase activity IEA
 molecular_functionGO:0004713 protein tyrosine kinase activity IEA
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0016301 kinase activity IEA
 molecular_functionGO:0016740 transferase activity IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0012307 impaired spatial learning "impaired ability to ascertain or acquire spatial location information in order to improve navigation or other behavior using such location cues" [MGI:csmith]
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Allelic Composition: Amotl2tm1.1Laho/Amotl2+,Tg(Cdh5-cre/ERT2)1Rha/0
Genetic Background: involves: C57BL/6

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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