ENSDARG00000001220


Danio rerio

Features
Gene ID: ENSDARG00000001220
  
Biological name :mycbp2
  
Synonyms : MYC binding protein 2 / mycbp2
  
Possible biological names infered from orthology : MYC binding protein 2, E3 ubiquitin protein ligase / O75592
  
Species: Danio rerio
  
Chr. number: 9
Strand: -1
Band:
Gene start: 17045875
Gene end: 17286330
  
Corresponding Affymetrix probe sets: Dr.17163.1.S1_at (Zebrafish Array)   NM_001012247_at (Zebrafish Genome Array with custom cdf files)   
  
Cross references: Ensembl peptide - ENSDARP00000028785
NCBI entrez gene - 368439     See in Manteia.
RefSeq - NM_001012247
RefSeq Peptide - NP_001012247
swissprot - F1RD40
ZFIN ID - ZDB-GENE-030616-132
Ensembl - ENSDARG00000001220
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 MYCBP2ENSGALG00000016915Gallus gallus
 MYCBP2ENSG00000005810Homo sapiens
 Mycbp2ENSMUSG00000033004Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
ibtk / inhibitor of Bruton agammaglobulinemia tyrosine kinase / Q6ZPR6* / Q9P2D0* / inhibitor of Bruton tyrosine kinase*ENSDARG000000744246


Protein motifs (from Interpro)
Interpro ID Name
 IPR000408  Regulator of chromosome condensation, RCC1
 IPR001841  Zinc finger, RING-type
 IPR003646  SH3-like domain, bacterial-type
 IPR004939  APC10/DOC domain
 IPR008979  Galactose-binding-like domain superfamily
 IPR009091  Regulator of chromosome condensation 1/beta-lactamase-inhibitor protein II
 IPR012983  PHR
 IPR013083  Zinc finger, RING/FYVE/PHD-type
 IPR013783  Immunoglobulin-like fold
 IPR014756  Immunoglobulin E-set
 IPR017868  Filamin/ABP280 repeat-like


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007411 axon guidance IMP
 biological_processGO:0016198 axon choice point recognition IMP
 biological_processGO:0016567 protein ubiquitination IEA
 biological_processGO:0021986 habenula development IMP
 biological_processGO:0031290 retinal ganglion cell axon guidance IMP
 biological_processGO:0042068 regulation of pteridine metabolic process IMP
 biological_processGO:0048066 developmental pigmentation IMP
 cellular_componentGO:0005737 cytoplasm IDA
 molecular_functionGO:0004842 ubiquitin-protein transferase activity IDA
 molecular_functionGO:0005515 protein binding IPI


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000359 habenular commissure habenular commissure aplastic , abnormal
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 ZFA:0000396 nervous system nervous system quality , abnormal
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 ZFA:0001094 whole organism whole organism lethal (sensu genetics) , abnormal
whole organism viability , abnormal
whole organism low saturation , abnormal
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 ZFA:0009090 pigment cell pigment cell quality , abnormal
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 ZFA:0009198 xanthophore xanthophore quality , abnormal
xanthophore low saturation , abnormal
xanthophore decreased pigmentation , abnormal
xanthophore decreased size , abnormal
xanthophore increased distribution , abnormal
xanthophore increased fluorescence , abnormal
xanthophore dendrite distributed , abnormal
xanthophore pigment granule condensed , abnormal
xanthophore pigment granule decreased amount , abnormal
xanthophore decreased amount , abnormal
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 ZFA:0009310 retinal ganglion cell retinal ganglion cell axon aggregated , abnormal
retinal ganglion cell axon displaced to eye ipsilateral side, abnormal
retinal ganglion cell axon irregular spatial pattern , abnormal
retinal ganglion cell axon displaced , abnormal
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Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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