ENSDARG00000004470


Danio rerio

Features
Gene ID: ENSDARG00000004470
  
Biological name :prkcsh
  
Synonyms : prkcsh / protein kinase C substrate 80K-H
  
Possible biological names infered from orthology : O08795 / P14314
  
Species: Danio rerio
  
Chr. number: 3
Strand: 1
Band:
Gene start: 46762703
Gene end: 46795783
  
Corresponding Affymetrix probe sets: Dr.1099.1.S1_at (Zebrafish Array)   NM_201053_at (Zebrafish Genome Array with custom cdf files)   
  
Cross references: Ensembl peptide - ENSDARP00000115082
Ensembl peptide - ENSDARP00000156386
Ensembl peptide - ENSDARP00000136544
Ensembl peptide - ENSDARP00000119154
Ensembl peptide - ENSDARP00000025069
NCBI entrez gene - 394028     See in Manteia.
RefSeq - NM_201053
RefSeq Peptide - NP_957347
swissprot - A0A0R4ILT4
swissprot - E9QHL2
swissprot - F1RBW3
swissprot - E9QBB3
ZFIN ID - ZDB-GENE-040426-770
Ensembl - ENSDARG00000004470
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 P14314ENSG00000130175Homo sapiens
 O08795ENSMUSG00000003402Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR002048  EF-hand domain
 IPR009011  Mannose-6-phosphate receptor binding domain superfamily
 IPR018247  EF-Hand 1, calcium-binding site
 IPR026874  Glucosidase 2 subunit beta
 IPR028146  Glucosidase II beta subunit, N-terminal


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001889 liver development IMP
 biological_processGO:0006491 N-glycan processing IEA
 biological_processGO:0048793 pronephros development IGI
 cellular_componentGO:0005783 endoplasmic reticulum ISS
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0005509 calcium ion binding IEA


Pathways (from Reactome)
Pathway description
Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)
N-glycan trimming in the ER and Calnexin/Calreticulin cycle
Post-translational protein phosphorylation
Calnexin/calreticulin cycle


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000123 liver liver cystic , abnormal
liver endoplasmic reticulum disoriented , abnormal
liver endoplasmic reticulum swollen , abnormal
Show

 ZFA:0000151 pronephros pronephros cystic , abnormal
Show

 ZFA:0001094 whole organism whole organism curved lateral , abnormal
Show

 ZFA:0001115 trunk trunk malformed , abnormal
trunk curved dorsal , abnormal
Show

 ZFA:0001117 post-vent region post-vent region kinked , abnormal
Show

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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