ENSDARG00000005891


Danio rerio

Features
Gene ID: ENSDARG00000005891
  
Biological name :cyb5r3
  
Synonyms : cyb5r3 / cytochrome b5 reductase 3
  
Possible biological names infered from orthology : NADH-cytochrome b5 reductase 3 NADH-cytochrome b5 reductase 3 membrane-bound form NADH-cytochrome b5 reductase 3 soluble form / P00387 / Q9DCN2
  
Species: Danio rerio
  
Chr. number: 4
Strand: -1
Band:
Gene start: 11804675
Gene end: 11810799
  
Corresponding Affymetrix probe sets: Dr.4481.1.A1_at (Zebrafish Array)   NM_212685_at (Zebrafish Genome Array with custom cdf files)   
  
Cross references: Ensembl peptide - ENSDARP00000014732
Ensembl peptide - ENSDARP00000125512
NCBI entrez gene - 324560     See in Manteia.
RefSeq - NM_212685
RefSeq Peptide - NP_997850
swissprot - H0WF81
swissprot - Q6NYE6
ZFIN ID - ZDB-GENE-030131-3281
Ensembl - ENSDARG00000005891
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 CYB5R3ENSGALG00000014122Gallus gallus
 CYB5R3ENSG00000100243Homo sapiens
 Cyb5r3ENSMUSG00000018042Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
cyb5r1 / cytochrome b5 reductase 1 / Q9DB73* / Q9UHQ9*ENSDARG0000001896666
cyb5r2 / Q0P487 / cytochrome b5 reductase 2 / Q6BCY4* / Q3KNK3* / NADH-cytochrome b5 reductase 2 *ENSDARG0000005192560
cyb5r4 / cytochrome b5 reductase 4 / Q7L1T6*ENSDARG0000002089824


Protein motifs (from Interpro)
Interpro ID Name
 IPR001433  Oxidoreductase FAD/NAD(P)-binding
 IPR001709  Flavoprotein pyridine nucleotide cytochrome reductase
 IPR001834  NADH:cytochrome b5 reductase (CBR)
 IPR008333  Oxidoreductase, FAD-binding domain
 IPR017927  Ferredoxin reductase-type FAD-binding domain
 IPR017938  Riboflavin synthase-like beta-barrel


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0055114 oxidation-reduction process IEA
 molecular_functionGO:0004128 cytochrome-b5 reductase activity, acting on NAD(P)H IEA
 molecular_functionGO:0016491 oxidoreductase activity IEA


Pathways (from Reactome)
Pathway description
Vitamin C (ascorbate) metabolism
Phase I - Functionalization of compounds
Neutrophil degranulation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSDARG00000098589 cyb5a / cytochrome b5 type A (microsomal) / P00167* / P56395* / Cytochrome b5 * / cytochrome b5 type A*  / reaction
 ENSDARG00000070487 zgc:110783 / MARC2* / MARC1* / Q5VT66* / Q922Q1* / Q969Z3* / Q9CW42* / mitochondrial amidoxime reducing component 2* / mitochondrial amidoxime reducing component 1*  / complex






 

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