ENSDARG00000010773


Danio rerio

Features
Gene ID: ENSDARG00000010773
  
Biological name :pnpla6
  
Synonyms : patatin-like phospholipase domain containing 6 / pnpla6
  
Possible biological names infered from orthology : Mus musculus patatin-like phospholipase domain containing 6 (Pnpla6), transcript variant 4, mRNA. / Q3TRM4 / Q8IY17
  
Species: Danio rerio
  
Chr. number: 1
Strand: -1
Band:
Gene start: 45866692
Gene end: 45920632
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSDARP00000122326
Ensembl peptide - ENSDARP00000123114
Ensembl peptide - ENSDARP00000116275
NCBI entrez gene - 560986     See in Manteia.
RefSeq - XM_001921173
RefSeq - XM_005160052
RefSeq - XM_005160053
swissprot - F1R844
swissprot - B8A657
swissprot - F6PC59
ZFIN ID - ZDB-GENE-050107-4
Ensembl - ENSDARG00000010773
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 PNPLA6ENSG00000032444Homo sapiens
 Pnpla6ENSMUSG00000004565Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
pnpla7b / patatin-like phospholipase domain containing 7b / A2AJ88* / PNPLA7* / Q6ZV29* / patatin like phospholipase domain containing 7* / Patatin-like phospholipase domain-containing protein 7 *ENSDARG0000004000258
clic3 / pnpla7a / patatin-like phospholipase domain containing 7a / Q6ZV29* / PNPLA7* / A2AJ88* / patatin like phospholipase domain containing 7* / Patatin-like phospholipase domain-contain...ENSDARG0000006298614


Protein motifs (from Interpro)
Interpro ID Name
 IPR000595  Cyclic nucleotide-binding domain
 IPR001423  Lysophospholipase patatin, conserved site
 IPR002641  Patatin-like phospholipase domain
 IPR014710  RmlC-like jelly roll fold
 IPR016035  Acyl transferase/acyl hydrolase/lysophospholipase
 IPR018490  Cyclic nucleotide-binding-like


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006629 lipid metabolic process IEA
 biological_processGO:0007409 axonogenesis IMP
 biological_processGO:0008152 metabolic process IEA
 biological_processGO:0009948 anterior/posterior axis specification IMP
 biological_processGO:0016042 lipid catabolic process IEA
 biological_processGO:0030514 negative regulation of BMP signaling pathway IMP
 biological_processGO:0046470 phosphatidylcholine metabolic process IEA
 biological_processGO:0048666 neuron development IMP
 cellular_componentGO:0005783 endoplasmic reticulum IBA
 molecular_functionGO:0004622 lysophospholipase activity IEA
 molecular_functionGO:0016787 hydrolase activity IEA
 molecular_functionGO:0052689 carboxylic ester hydrolase activity ISS


Pathways (from Reactome)
Pathway description
Glycerophospholipid catabolism


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000012 central nervous system central nervous system apoptotic , abnormal
Show

 ZFA:0000042 midbrain hindbrain boundary midbrain hindbrain boundary morphology , abnormal
Show

 ZFA:0000051 otic vesicle otic vesicle decreased size , abnormal
Show

 ZFA:0000054 pericardium pericardium edematous , abnormal
Show

 ZFA:0000107 eye eye decreased size , abnormal
Show

 ZFA:0001094 whole organism whole organism anterior-posterior axis shortened , abnormal
Show

 ZFA:0001114 head head decreased size , abnormal
Show

 ZFA:0001115 trunk trunk curved , abnormal
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 ZFA:0001117 post-vent region post-vent region increased curvature , abnormal
post-vent region curved , abnormal
Show

 ZFA:0009052 motor neuron motor neuron decreased amount , abnormal
motor neuron axon branched , abnormal
motor neuron axon truncated , abnormal
Show

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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