ENSDARG00000012261


Danio rerio

Features
Gene ID: ENSDARG00000012261
  
Biological name :eftud2
  
Synonyms : eftud2 / elongation factor Tu GTP binding domain containing 2
  
Possible biological names infered from orthology : 116 kDa U5 small nuclear ribonucleoprotein component / O08810 / Q15029
  
Species: Danio rerio
  
Chr. number: 3
Strand: -1
Band:
Gene start: 16389020
Gene end: 16413635
  
Corresponding Affymetrix probe sets: Dr.2332.1.S1_at (Zebrafish Array)   
  
Cross references: Ensembl peptide - ENSDARP00000028033
Ensembl peptide - ENSDARP00000115252
Ensembl peptide - ENSDARP00000114493
Ensembl peptide - ENSDARP00000112204
NCBI entrez gene - 393480     See in Manteia.
RefSeq - NM_200508
RefSeq Peptide - NP_956802
swissprot - E7FGW2
swissprot - E9QH15
swissprot - F1Q6N0
swissprot - E9QFC1
ZFIN ID - ZDB-GENE-040426-1569
Ensembl - ENSDARG00000012261
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 EFTUD2ENSGALG00000000988Gallus gallus
 EFTUD2ENSG00000108883Homo sapiens
 Eftud2ENSMUSG00000020929Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR000640  Elongation factor EFG, domain V-like
 IPR000795  Transcription factor, GTP-binding domain
 IPR004161  Translation elongation factor EFTu-like, domain 2
 IPR005225  Small GTP-binding protein domain
 IPR005517  Translation elongation factor EFG/EF2, domain IV
 IPR009000  Translation protein, beta-barrel domain superfamily
 IPR014721  Ribosomal protein S5 domain 2-type fold, subgroup
 IPR020568  Ribosomal protein S5 domain 2-type fold
 IPR027417  P-loop containing nucleoside triphosphate hydrolase
 IPR031950  116kDa U5 small nuclear ribonucleoprotein component, N-terminal
 IPR035647  EF-G domain III/V-like
 IPR035655  116kDa U5 small nuclear ribonucleoprotein component, C-terminal


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000398 mRNA splicing, via spliceosome IMP
 biological_processGO:0043010 camera-type eye development IMP
 biological_processGO:0045664 regulation of neuron differentiation IMP
 biological_processGO:0048666 neuron development IMP
 biological_processGO:0060322 head development IMP
 molecular_functionGO:0003924 GTPase activity IEA
 molecular_functionGO:0005525 GTP binding IEA


Pathways (from Reactome)
Pathway description
mRNA Splicing - Major Pathway
mRNA Splicing - Minor Pathway


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000008 brain brain apoptotic process increased occurrence , abnormal
brain morphology , abnormal
brain cell proliferation increased occurrence , abnormal
brain neuron decreased amount , abnormal
Show

 ZFA:0000012 central nervous system central nervous system apoptotic process increased occurrence , abnormal
Show

 ZFA:0000037 anatomical structure anatomical structure absent , abnormal
anatomical structure increased amount , abnormal
Show

 ZFA:0000075 spinal cord spinal cord apoptotic process increased occurrence , abnormal
spinal cord cell proliferation increased occurrence , abnormal
spinal cord glial cell deformed , abnormal
spinal cord neuroblast (sensu Vertebrata) deformed , abnormal
Show

 ZFA:0000107 eye eye decreased diameter , abnormal
eye perforate , abnormal
eye decreased size , abnormal
Show

 ZFA:0000152 retina retina cell death increased occurrence , abnormal
retina ventral region decreased thickness , abnormal
retina apoptotic process increased occurrence , abnormal
Show

 ZFA:0000445 optic tectum optic tectum apoptotic process increased occurrence , abnormal
Show

 ZFA:0001058 caudal fin caudal fin curved dorsal , abnormal
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 ZFA:0001094 whole organism whole organism apoptotic process increased occurrence , abnormal
whole organism anterior-posterior axis decreased length , abnormal
whole organism dead , abnormal
Show

 ZFA:0001114 head head decreased size , abnormal
head dorsal-ventral axis decreased height , abnormal
head apoptotic , abnormal
Show

 ZFA:0001284 optic fissure optic fissure closure incomplete , abnormal
Show

 ZFA:0001306 pharyngeal arch pharyngeal arch apoptotic process increased occurrence , abnormal
Show

 ZFA:0009168 neuroblast (sensu Vertebrata) neuroblast (sensu Vertebrata) apoptotic process increased occurrence , abnormal
Show

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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