ENSDARG00000013963


Danio rerio

Features
Gene ID: ENSDARG00000013963
  
Biological name :mipb
  
Synonyms : major intrinsic protein of lens fiber b / mipb
  
Possible biological names infered from orthology : Lens fiber major intrinsic protein / major intrinsic protein of lens fiber / MIP / P30301 / P51180
  
Species: Danio rerio
  
Chr. number: 23
Strand: -1
Band:
Gene start: 6637611
Gene end: 6641223
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSDARP00000005361
NCBI entrez gene - 553420     See in Manteia.
RefSeq - NM_001020520
RefSeq Peptide - NP_001018356
swissprot - Q4ZJI3
ZFIN ID - ZDB-GENE-050706-86
Ensembl - ENSDARG00000013963
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 MIPENSGALG00000042119Gallus gallus
 MIPENSG00000135517Homo sapiens
 MipENSMUSG00000025389Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
mipa / major intrinsic protein of lens fiber a / MIP* / P30301* / P51180* / Lens fiber major intrinsic protein * / major intrinsic protein of lens fiber*ENSDARG0000003728585
aqp1a.2 / aquaporin 1a (Colton blood group), tandem duplicate 2 / AQP1* / P29972* / AC004691.2* / aquaporin 1 (Colton blood group)*ENSDARG0000009102744
aqp4 / aquaporin 4 / P55087* / aquaporin-4 isoform M1x *ENSDARG0000001056543
aqp1a.1 / aquaporin 1a (Colton blood group), tandem duplicate 1 / AQP1* / P29972* / AC004691.2* / aquaporin 1 (Colton blood group)*ENSDARG0000002371342
CR450824.2ENSDARG0000010392731
CT573446.1ENSDARG0000010500729
aqp8a.1 / aquaporin 8a, tandem duplicate 1 / AQP8* / O94778* / P56404* / aquaporin 8*ENSDARG0000004514127
aqp8a.2 / aquaporin 8a, tandem duplicate 2ENSDARG0000007159226
aqp8b / aquaporin 8bENSDARG0000008974925


Protein motifs (from Interpro)
Interpro ID Name
 IPR000425  Major intrinsic protein
 IPR022357  Major intrinsic protein, conserved site
 IPR023271  Aquaporin-like
 IPR034294  Aquaporin transporter


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0002088 lens development in camera-type eye IMP
 biological_processGO:0006833 water transport IEA
 biological_processGO:0034220 ion transmembrane transport IBA
 biological_processGO:0055085 transmembrane transport IEA
 cellular_componentGO:0005887 integral component of plasma membrane IBA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0016324 apical plasma membrane IBA
 molecular_functionGO:0005372 water transmembrane transporter activity IDA
 molecular_functionGO:0015267 channel activity IEA


Pathways (from Reactome)
Pathway description
Passive transport by Aquaporins


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000035 lens lens rough , abnormal
lens opaque , abnormal
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Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSDARG00000037285 mipa / major intrinsic protein of lens fiber a / MIP* / P30301* / P51180* / Lens fiber major intrinsic protein * / major intrinsic protein of lens fiber*  / complex
 ENSDARG00000013963 mipb / major intrinsic protein of lens fiber b / MIP* / P30301* / P51180* / Lens fiber major intrinsic protein * / major intrinsic protein of lens fiber*  / complex






 

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